FR2085665A1 - - Google Patents

Info

Publication number
FR2085665A1
FR2085665A1 FR7107367A FR7107367A FR2085665A1 FR 2085665 A1 FR2085665 A1 FR 2085665A1 FR 7107367 A FR7107367 A FR 7107367A FR 7107367 A FR7107367 A FR 7107367A FR 2085665 A1 FR2085665 A1 FR 2085665A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7107367A
Other languages
French (fr)
Other versions
FR2085665B1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of FR2085665A1 publication Critical patent/FR2085665A1/fr
Application granted granted Critical
Publication of FR2085665B1 publication Critical patent/FR2085665B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7107367A 1970-03-03 1971-03-03 Expired FR2085665B1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19702009743 DE2009743A1 (de) 1970-03-03 1970-03-03 Substituierte Biguanide mit antihyperglykämischer Wirkung

Publications (2)

Publication Number Publication Date
FR2085665A1 true FR2085665A1 (xx) 1971-12-31
FR2085665B1 FR2085665B1 (xx) 1974-08-30

Family

ID=5763819

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7107367A Expired FR2085665B1 (xx) 1970-03-03 1971-03-03

Country Status (11)

Country Link
AT (1) AT302350B (xx)
BE (1) BE763725A (xx)
CH (2) CH564526A5 (xx)
DE (1) DE2009743A1 (xx)
ES (2) ES388863A1 (xx)
FR (1) FR2085665B1 (xx)
GB (1) GB1343831A (xx)
IE (1) IE34966B1 (xx)
IL (1) IL36271A0 (xx)
NL (1) NL7102612A (xx)
ZA (1) ZA711269B (xx)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0507317A2 (en) * 1991-04-05 1992-10-07 Otsuka Pharmaceutical Co., Ltd. Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
US6303661B1 (en) 1996-04-25 2001-10-16 Probiodrug Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals
US6319893B1 (en) 1998-07-31 2001-11-20 Probiodrug Raising blood sugar level in hypoglycemic mammals by administering inhibitors of dipeptidyl peptidase IV
WO2002074740A1 (en) * 2001-03-21 2002-09-26 Merck Patent Gmbh Biguanide derivatives
US6500804B2 (en) 2000-03-31 2002-12-31 Probiodrug Ag Method for the improvement of islet signaling in diabetes mellitus and for its prevention
US6559314B2 (en) 1999-06-10 2003-05-06 Probiodrug Ag Method for the production of thiazolidin
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US6946480B2 (en) 2002-02-28 2005-09-20 Hans-Ulrich Demuth Glutaminyl based DPIV inhibitors
US7053055B2 (en) 1998-06-24 2006-05-30 Prosidion Ltd. Compounds of unstable DP IV-inhibitors
US7109347B2 (en) 2001-06-27 2006-09-19 Probiodrug Ag Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
US7166579B2 (en) 1998-06-24 2007-01-23 Prosidion Limited Prodrugs of DP IV-inhibitors
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
US7371871B2 (en) 2003-05-05 2008-05-13 Probiodrug Ag Inhibitors of glutaminyl cyclase
US7381537B2 (en) 2003-05-05 2008-06-03 Probiodrug Ag Use of inhibitors of glutaminyl cyclases for treatment and prevention of disease
US7608577B2 (en) 2001-10-12 2009-10-27 Osi Pharmaceuticals, Inc. Peptidyl ketones as inhibitors of DPIV
US7897633B2 (en) 2004-02-05 2011-03-01 Probiodrug Ag Inhibitors of glutaminyl cyclase

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003224917A1 (en) 2002-04-11 2003-10-27 Carbomer Diabetes imaging probes
CN110615886A (zh) * 2019-09-05 2019-12-27 哈尔滨工程大学 一种双胍衍生物抗菌型环氧树脂固化剂及其制备方法
CN115960018B (zh) * 2022-12-19 2024-01-05 湖南岳靶生物医药有限公司 一种egfr抑制剂、组合物及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR940304A (fr) * 1946-01-07 1948-12-09 Ici Ltd Procédé de fabrication de dérivés de biguanides
FR1053761A (fr) * 1949-01-31 1954-02-04 Ici Ltd Fabrication de dérivés de la biguanide
FR2100M (fr) * 1961-01-18 1963-10-28 Us Vitamin Pharm Corp Alkoxypropyl-biguanides.
FR6786M (xx) * 1967-08-10 1969-03-17

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR940304A (fr) * 1946-01-07 1948-12-09 Ici Ltd Procédé de fabrication de dérivés de biguanides
FR1053761A (fr) * 1949-01-31 1954-02-04 Ici Ltd Fabrication de dérivés de la biguanide
FR2100M (fr) * 1961-01-18 1963-10-28 Us Vitamin Pharm Corp Alkoxypropyl-biguanides.
FR6786M (xx) * 1967-08-10 1969-03-17

Cited By (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0507317A3 (en) * 1991-04-05 1993-02-24 Otsuka Pharmaceutical Co., Ltd. Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
US5376686A (en) * 1991-04-05 1994-12-27 Otsuka Pharmaceutical Co., Ltd. Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
EP0507317A2 (en) * 1991-04-05 1992-10-07 Otsuka Pharmaceutical Co., Ltd. Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
US6303661B1 (en) 1996-04-25 2001-10-16 Probiodrug Use of dipeptidyl peptidase IV effectors for lowering the blood glucose level in mammals
US7053055B2 (en) 1998-06-24 2006-05-30 Prosidion Ltd. Compounds of unstable DP IV-inhibitors
US7166579B2 (en) 1998-06-24 2007-01-23 Prosidion Limited Prodrugs of DP IV-inhibitors
US6319893B1 (en) 1998-07-31 2001-11-20 Probiodrug Raising blood sugar level in hypoglycemic mammals by administering inhibitors of dipeptidyl peptidase IV
US6559314B2 (en) 1999-06-10 2003-05-06 Probiodrug Ag Method for the production of thiazolidin
US6500804B2 (en) 2000-03-31 2002-12-31 Probiodrug Ag Method for the improvement of islet signaling in diabetes mellitus and for its prevention
US7435420B2 (en) 2000-10-27 2008-10-14 Probiodrug Ag Dipeptidyl peptidase IV inhibitors for the treatment of anxiety
US7132104B1 (en) 2000-10-27 2006-11-07 Probiodrug Ag Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
FR2822464A1 (fr) * 2001-03-21 2002-09-27 Lipha Derives biguanides et leurs applications en therapeutique
WO2002074740A1 (en) * 2001-03-21 2002-09-26 Merck Patent Gmbh Biguanide derivatives
US7285681B2 (en) 2001-03-21 2007-10-23 Merck Patent Gesellschaft Biguanide derivatives
US6890905B2 (en) 2001-04-02 2005-05-10 Prosidion Limited Methods for improving islet signaling in diabetes mellitus and for its prevention
US7368421B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
US7109347B2 (en) 2001-06-27 2006-09-19 Probiodrug Ag Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7368576B2 (en) 2001-06-27 2008-05-06 Probiodrug Ag Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
US7144856B2 (en) 2001-09-06 2006-12-05 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
US6844316B2 (en) 2001-09-06 2005-01-18 Probiodrug Ag Inhibitors of dipeptidyl peptidase I
US7608577B2 (en) 2001-10-12 2009-10-27 Osi Pharmaceuticals, Inc. Peptidyl ketones as inhibitors of DPIV
US6946480B2 (en) 2002-02-28 2005-09-20 Hans-Ulrich Demuth Glutaminyl based DPIV inhibitors
US7371871B2 (en) 2003-05-05 2008-05-13 Probiodrug Ag Inhibitors of glutaminyl cyclase
US7381537B2 (en) 2003-05-05 2008-06-03 Probiodrug Ag Use of inhibitors of glutaminyl cyclases for treatment and prevention of disease
US7897633B2 (en) 2004-02-05 2011-03-01 Probiodrug Ag Inhibitors of glutaminyl cyclase

Also Published As

Publication number Publication date
ES391629A1 (es) 1974-09-16
CH553756A (de) 1974-09-13
IE34966B1 (en) 1975-10-01
AT302350B (de) 1972-10-10
BE763725A (xx) 1971-09-03
IL36271A0 (en) 1971-04-28
NL7102612A (xx) 1971-09-07
GB1343831A (en) 1974-01-16
CH564526A5 (xx) 1975-07-31
IE34966L (en) 1971-09-03
ES388863A1 (es) 1973-06-01
DE2009743A1 (de) 1971-09-16
ZA711269B (en) 1971-11-24
FR2085665B1 (xx) 1974-08-30

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Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse