FR2020689B1 - - Google Patents

Info

Publication number
FR2020689B1
FR2020689B1 FR6935200A FR6935200A FR2020689B1 FR 2020689 B1 FR2020689 B1 FR 2020689B1 FR 6935200 A FR6935200 A FR 6935200A FR 6935200 A FR6935200 A FR 6935200A FR 2020689 B1 FR2020689 B1 FR 2020689B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR6935200A
Other versions
FR2020689A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of FR2020689A1 publication Critical patent/FR2020689A1/fr
Application granted granted Critical
Publication of FR2020689B1 publication Critical patent/FR2020689B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0046—Ear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23D—PLANING; SLOTTING; SHEARING; BROACHING; SAWING; FILING; SCRAPING; LIKE OPERATIONS FOR WORKING METAL BY REMOVING MATERIAL, NOT OTHERWISE PROVIDED FOR
    • B23D33/00—Accessories for shearing machines or shearing devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
FR6935200A 1968-10-14 1969-10-14 Expired FR2020689B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB48643/68A GB1281689A (en) 1968-10-14 1968-10-14 Steroid 21-phosphates

Publications (2)

Publication Number Publication Date
FR2020689A1 FR2020689A1 (fr) 1970-07-17
FR2020689B1 true FR2020689B1 (fr) 1973-12-21

Family

ID=10449381

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6935200A Expired FR2020689B1 (fr) 1968-10-14 1969-10-14

Country Status (7)

Country Link
US (1) US3764616A (fr)
JP (1) JPS4838701B1 (fr)
CH (1) CH567521A5 (fr)
DE (1) DE1951790C3 (fr)
FR (1) FR2020689B1 (fr)
GB (1) GB1281689A (fr)
NL (1) NL162659C (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966778A (en) * 1965-05-08 1976-06-29 Takeda Chemical Industries, Ltd. Production of 21-phosphate corticords having unprotected hydroxyl radicals at least at the 17α- and 21-position
SE418294B (sv) * 1974-03-27 1981-05-18 Plurichemie Anstalt Sett att framstella en 16alfa- eller 16beta-9alfa-klor eller -fluorsteroidester
DE2817988A1 (de) * 1978-04-25 1979-11-08 Hoechst Ag Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
US8546362B2 (en) 2009-04-13 2013-10-01 Vanangamudi Subramaniam Sulur Medicinal cream made using neomycin sulphate, betamethasone valerate, and chitosan, and a process to make the same
TW201609183A (zh) 2013-10-31 2016-03-16 康諾普堤克斯公司 眼用調配物之製備方法及其用途
CN104610413B (zh) * 2013-11-05 2016-04-20 河南利华制药有限公司 泼尼松龙磷酸酯纯化工艺
CN109734766B (zh) * 2019-01-07 2020-09-04 河南利华制药有限公司 一种泼尼松龙磷酸钠中间体的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA792233A (en) * 1968-08-13 Elks Joseph Steroid derivatives of the pregnane or allopregnane series
US2912446A (en) * 1955-01-14 1959-11-10 Merck & Co Inc delta1, 4-3, 20-diketo-11-oxygenated-17alpha-hydroxy-pregnadienes and 9-fluoro derivatives thereof
US2967179A (en) * 1958-04-18 1961-01-03 Glaxo Lab Ltd Diamine salts of 21-phosphate esters of steroid compounds of the pregnane and allopregnane series
GB913941A (en) * 1958-08-01 1962-12-28 Merck & Co Inc Steroid compounds
FR1365253A (fr) * 1959-08-08 1964-07-03 Glaxo Lab Ltd Nouveaux esters phosphoriques de stéroïdes et leur procédé de préparation
US3064016A (en) * 1959-10-29 1962-11-13 Vermehren Carl Emil Cortical hormone derivatives of phosphoric acid and alkali metal salts thereof
US3073816A (en) * 1959-11-26 1963-01-15 Merck Ag E Process of producing 21-orthophosphates of steroids and the 21-diamide orthophosphate intermediates therefor
US3099654A (en) * 1960-08-17 1963-07-30 Roussel Uclaf Novel 9alpha-fluoro-delta1-corticosteroids and preparation thereof
US3053834A (en) * 1961-01-26 1962-09-11 Olin Mathieson 21-phosphates of steroid acetals and ketals
GB1047518A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
FR1478978A (fr) * 1965-05-08 1967-04-28 Takeda Chemical Industries Ltd Procédé de préparation et de purification des phosphate-21-stéroïdes du type corticoïde
ES372667A1 (es) * 1969-05-08 1971-12-16 Chimico Farmaceutico Dr P Blas Procedimiento para preparar derivados de esteroides.

Also Published As

Publication number Publication date
NL6915501A (fr) 1970-04-16
DE1951790C3 (de) 1978-10-26
NL162659B (nl) 1980-01-15
CH567521A5 (fr) 1975-10-15
GB1281689A (en) 1972-07-12
NL162659C (nl) 1980-06-16
JPS4838701B1 (fr) 1973-11-19
DE1951790A1 (de) 1970-06-18
FR2020689A1 (fr) 1970-07-17
DE1951790B2 (de) 1978-03-09
US3764616A (en) 1973-10-09

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Legal Events

Date Code Title Description
ST Notification of lapse