FR2014309A1 - 2-4-thiazolyl benzimidazole derivs anthelmintics - Google Patents

2-4-thiazolyl benzimidazole derivs anthelmintics

Info

Publication number
FR2014309A1
FR2014309A1 FR6921533A FR6921533A FR2014309A1 FR 2014309 A1 FR2014309 A1 FR 2014309A1 FR 6921533 A FR6921533 A FR 6921533A FR 6921533 A FR6921533 A FR 6921533A FR 2014309 A1 FR2014309 A1 FR 2014309A1
Authority
FR
France
Prior art keywords
anthelmintics
thiazolyl benzimidazole
derivs
benzimidazole derivs
thiazolyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR6921533A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck et Cie
Merck and Co Inc
Original Assignee
Merck et Cie
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck et Cie, Merck and Co Inc filed Critical Merck et Cie
Publication of FR2014309A1 publication Critical patent/FR2014309A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/10—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

(A) Cpds. (I) R =(1-10C) Oalkyl, Ph, or p-F.C6H4, at postn.5(6). (B) Salts of I Anthelmintics. Dose 5-125 mg/kg. HCSNH2 (0.2 mol) was added (15 mins.) to 2-(2-bromoacetyl)-5(6)-isopropoxycarbonylaminobenzimidazole (0.1 mol) in EtOH (50 ml) at 0 deg., warmed (1 h.) to 25 deg., stirred 48 h., poured into ice-water, neutralised with NaHCO3, filtered, washed, and recryst. from 50% MeOH.Aq., giving I, m.p.240-2 deg.
FR6921533A 1968-06-27 1969-06-26 2-4-thiazolyl benzimidazole derivs anthelmintics Withdrawn FR2014309A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA23741 1968-06-27

Publications (1)

Publication Number Publication Date
FR2014309A1 true FR2014309A1 (en) 1970-04-17

Family

ID=4084326

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6921533A Withdrawn FR2014309A1 (en) 1968-06-27 1969-06-26 2-4-thiazolyl benzimidazole derivs anthelmintics

Country Status (10)

Country Link
AT (1) AT291992B (en)
BR (1) BR6910199D0 (en)
CH (1) CH521985A (en)
DK (1) DK130530B (en)
ES (3) ES368716A1 (en)
FR (1) FR2014309A1 (en)
NL (1) NL6909078A (en)
PL (1) PL80109B1 (en)
SE (1) SE343862B (en)
YU (1) YU32808B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3131535A1 (en) 2022-01-01 2023-07-07 Formule&Sens Cosmetic composition comprising a wax of vegetable origin, an oil or a butter of vegetable origin, an N acyl amino acid salt, a particular water-insoluble powder and a particular polyol.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3131535A1 (en) 2022-01-01 2023-07-07 Formule&Sens Cosmetic composition comprising a wax of vegetable origin, an oil or a butter of vegetable origin, an N acyl amino acid salt, a particular water-insoluble powder and a particular polyol.

Also Published As

Publication number Publication date
DK130530B (en) 1975-03-03
BR6910199D0 (en) 1973-02-08
YU32808B (en) 1975-08-31
YU155569A (en) 1974-12-31
SE343862B (en) 1972-03-20
DK130530C (en) 1975-08-04
AT291992B (en) 1971-08-10
ES368716A1 (en) 1971-10-16
ES390398A1 (en) 1973-06-01
CH521985A (en) 1972-04-30
ES390396A1 (en) 1973-06-01
PL80109B1 (en) 1975-08-30
NL6909078A (en) 1969-12-30

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Legal Events

Date Code Title Description
ST Notification of lapse