FR2002284A1 - - Google Patents

Info

Publication number
FR2002284A1
FR2002284A1 FR6904336A FR6904336A FR2002284A1 FR 2002284 A1 FR2002284 A1 FR 2002284A1 FR 6904336 A FR6904336 A FR 6904336A FR 6904336 A FR6904336 A FR 6904336A FR 2002284 A1 FR2002284 A1 FR 2002284A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6904336A
Other languages
French (fr)
Other versions
FR2002284B1 (US06826419-20041130-M00005.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FR2002284A1 publication Critical patent/FR2002284A1/fr
Application granted granted Critical
Publication of FR2002284B1 publication Critical patent/FR2002284B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR696904336A 1968-02-20 1969-02-20 Expired FR2002284B1 (US06826419-20041130-M00005.png)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US70680268A 1968-02-20 1968-02-20

Publications (2)

Publication Number Publication Date
FR2002284A1 true FR2002284A1 (US06826419-20041130-M00005.png) 1969-10-17
FR2002284B1 FR2002284B1 (US06826419-20041130-M00005.png) 1973-07-13

Family

ID=24839099

Family Applications (1)

Application Number Title Priority Date Filing Date
FR696904336A Expired FR2002284B1 (US06826419-20041130-M00005.png) 1968-02-20 1969-02-20

Country Status (10)

Country Link
US (2) US3557142A (US06826419-20041130-M00005.png)
JP (1) JPS4843740B1 (US06826419-20041130-M00005.png)
BE (1) BE728675A (US06826419-20041130-M00005.png)
BR (1) BR6906477D0 (US06826419-20041130-M00005.png)
CH (1) CH507238A (US06826419-20041130-M00005.png)
DE (1) DE1908541A1 (US06826419-20041130-M00005.png)
FR (1) FR2002284B1 (US06826419-20041130-M00005.png)
GB (1) GB1206915A (US06826419-20041130-M00005.png)
NL (1) NL6902641A (US06826419-20041130-M00005.png)
SE (1) SE350259B (US06826419-20041130-M00005.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2218098A1 (US06826419-20041130-M00005.png) * 1973-02-16 1974-09-13 Labaz

Families Citing this family (83)

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FR7337M (US06826419-20041130-M00005.png) * 1968-01-11 1969-10-13
FR2096868B1 (US06826419-20041130-M00005.png) * 1970-07-08 1974-02-01 Roussel Uclaf
GB1318300A (en) * 1970-12-09 1973-05-23 Labaz Indole derivatives nad compositions containing the same
US4021448A (en) * 1975-10-21 1977-05-03 Sterling Drug Inc. 2-Substituted-indole-1-lower-alkanecarboxamides
US4233312A (en) * 1976-01-21 1980-11-11 Roussel Uclaf Esters of indole-1-acetic acid and analgesic use thereof
SE421917B (sv) * 1976-01-21 1982-02-08 Roussel Uclaf Analogiforfarande for framstellning av nya derivat av 2-metyl-1-indolyl-ettikssyra med terapeutisk verkan
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
US5229413A (en) * 1989-05-05 1993-07-20 G. D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
US5137910A (en) * 1989-05-05 1992-08-11 C.D. Searle & Co. Compositions containing indole-2-carboxylate compounds for treatment of CNS disorders
EP0603278A1 (en) * 1991-09-11 1994-06-29 Fujisawa Pharmaceutical Co., Ltd. Indole derivatives as 5-alpha-reductase inhibitor
GB9204024D0 (en) * 1992-02-25 1992-04-08 Fujisawa Pharmaceutical Co Indole derivatives
GB9204365D0 (en) * 1992-02-28 1992-04-08 Pfizer Ltd Indoles
ES2099007B1 (es) * 1993-07-16 1997-12-01 Pfizer Res & Dev Derivados de indol.
GB9716657D0 (en) 1997-08-07 1997-10-15 Zeneca Ltd Chemical compounds
GB9803226D0 (en) * 1998-02-17 1998-04-08 Zeneca Ltd Chemical compounds
ID27884A (id) 1998-03-31 2001-05-03 Inst For Pharm Discovery Inc Asam-asam indolealkanoat yang disubstitusikan.
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
GB9902459D0 (en) * 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902452D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902461D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902455D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
GB9902453D0 (en) 1999-02-05 1999-03-24 Zeneca Ltd Chemical compounds
JP3893026B2 (ja) * 1999-02-10 2007-03-14 アストラゼネカ アクチボラグ 血管形成阻害剤としてのキナゾリン誘導体
GB0000625D0 (en) 2000-01-13 2000-03-01 Zeneca Ltd Chemical compounds
TWI224101B (en) * 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
ES2290318T3 (es) * 2001-06-20 2008-02-16 Wyeth Derivados sustituidos de acido indolico como inhibidores del inhibidor del activador del plasminogeno-1 (pai-1).
TWI317634B (en) * 2001-12-13 2009-12-01 Nat Health Research Institutes Aroyl indoles compounds
US7632955B2 (en) * 2001-12-13 2009-12-15 National Health Research Institutes Indole compounds
US7528165B2 (en) * 2001-12-13 2009-05-05 National Health Research Institutes Indole compounds
EP1515721A4 (en) * 2002-06-14 2006-07-26 Merck & Co Inc OPHTHALMIC COMPOSITIONS FOR TREATING OCULAR HYPERTENSION
BR0312972A (pt) * 2002-07-26 2005-06-14 Inst For Pharm Discovery Inc Derivado de ácidos indolalcanóicos substituìdos e formulações contendo o mesmo para o uso no tratamento de complicações diabéticas
DK1569900T3 (da) * 2002-12-10 2006-10-23 Wyeth Corp Substituerede 3-carbonyl-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1)
EP1569902B1 (en) * 2002-12-10 2009-05-06 Wyeth Substituted indole oxo-acetyl amino acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
AU2003297727A1 (en) * 2002-12-10 2004-06-30 Wyeth Substituted 3-alkyl and 3-arylalkyl 1h-indol-1-yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (pai-1)
DE60324183D1 (en) * 2002-12-10 2008-11-27 Wyeth Corp Aryl-, aryloxy- und alkyloxysubstituierte 1h-indol-3-yl-glyoxylsäurederivateals inhibitoren des plasminogenaktivatorinhibitors-1 (pai-1)
UA80453C2 (en) * 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
DE60336646D1 (de) * 2003-08-07 2011-05-19 Nat Health Research Institutes Indol-Verbindungen als Inhibitoren der Tubulin-Polymerisation zur Behandlung von angiogenesisbezogenen Erkrankungen
US7268159B2 (en) * 2003-09-25 2007-09-11 Wyeth Substituted indoles
US7332521B2 (en) * 2003-09-25 2008-02-19 Wyeth Substituted indoles
US7582773B2 (en) * 2003-09-25 2009-09-01 Wyeth Substituted phenyl indoles
US7163954B2 (en) * 2003-09-25 2007-01-16 Wyeth Substituted naphthyl benzothiophene acids
US7342039B2 (en) * 2003-09-25 2008-03-11 Wyeth Substituted indole oximes
US7420083B2 (en) * 2003-09-25 2008-09-02 Wyeth Substituted aryloximes
US7141592B2 (en) * 2003-09-25 2006-11-28 Wyeth Substituted oxadiazolidinediones
US7446201B2 (en) * 2003-09-25 2008-11-04 Wyeth Substituted heteroaryl benzofuran acids
US7442805B2 (en) * 2003-09-25 2008-10-28 Wyeth Substituted sulfonamide-indoles
US7265148B2 (en) * 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
US7411083B2 (en) * 2003-09-25 2008-08-12 Wyeth Substituted acetic acid derivatives
US7534894B2 (en) 2003-09-25 2009-05-19 Wyeth Biphenyloxy-acids
US7351726B2 (en) * 2003-09-25 2008-04-01 Wyeth Substituted oxadiazolidinediones
GB0324763D0 (en) * 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
US7754747B2 (en) * 2004-08-23 2010-07-13 Wyeth Llc Oxazolo-naphthyl acids
JP2008510816A (ja) * 2004-08-23 2008-04-10 ワイス チアゾロ−ナフチル酸
MX2007002177A (es) * 2004-08-23 2007-04-02 Wyeth Corp Acidos de pirrolo-naftilo como inhibidores de pai-1.
US7531568B2 (en) * 2004-11-30 2009-05-12 Plexxikon, Inc. PPAR active compounds
WO2006060535A2 (en) * 2004-11-30 2006-06-08 Plexxikon, Inc. Indole derivatives for use as ppar active compounds
CA2592378A1 (en) * 2004-12-21 2006-06-29 Abbott Laboratories 3-cycloalkylcarbonyl indoles as cannabinoid receptor ligands
US7456289B2 (en) * 2004-12-31 2008-11-25 National Health Research Institutes Anti-tumor compounds
WO2007022321A2 (en) * 2005-08-17 2007-02-22 Wyeth Substituted indoles and use thereof
CN101304992A (zh) * 2005-09-07 2008-11-12 普莱希科公司 用作ppar调节剂的1,3-二取代吲哚衍生物
EP2024349B1 (en) * 2006-05-31 2017-08-02 AbbVie Inc. Compounds as cannabinoid receptor ligands and uses thereof
US8841334B2 (en) * 2006-05-31 2014-09-23 Abbvie Inc. Compounds as cannabinoid receptor ligands and uses thereof
US7999119B2 (en) 2006-07-22 2011-08-16 Oxagen Limited Compounds having CRTH2 antagonist activity
PE20090159A1 (es) * 2007-03-08 2009-02-21 Plexxikon Inc COMPUESTOS DERIVADOS DE ACIDO INDOL-PROPIONICO COMO MODULADORES PPARs
MX2009010363A (es) 2007-03-28 2009-12-04 Abbott Lab Compuestos de 1,3-tiazol-2(3h)-ilideno como ligandos del receptor canabinoide.
US7872033B2 (en) * 2007-04-17 2011-01-18 Abbott Laboratories Compounds as cannabinoid receptor ligands
WO2008144360A1 (en) * 2007-05-18 2008-11-27 Abbott Laboratories Novel compounds as cannabinoid receptor ligands
US9193713B2 (en) * 2007-10-12 2015-11-24 Abbvie Inc. Compounds as cannabinoid receptor ligands
US7750027B2 (en) 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
CA2712017C (en) 2008-01-18 2016-08-09 Oxagen Limited Compounds having crth2 antagonist activity
WO2009093026A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
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GB2457040A (en) * 2008-01-30 2009-08-05 Oxagen Ltd 1-Acetic acid indole derivatives with PGD2 activity
US8846730B2 (en) * 2008-09-08 2014-09-30 Abbvie Inc. Compounds as cannabinoid receptor ligands
ES2556752T3 (es) * 2008-09-16 2016-01-20 Abbvie Bahamas Ltd. Ligandos de receptores cannabinoides
PA8854001A1 (es) * 2008-12-16 2010-07-27 Abbott Lab Compuestos novedosos como ligandos de receptores de canabinoides
CN103086943B (zh) * 2011-11-04 2015-04-15 山东亨利医药科技有限责任公司 作为crth2受体拮抗剂的吲哚类衍生物
US8715529B1 (en) 2012-01-23 2014-05-06 Arrowhead Center, Inc. Synthesis and applications of triazaborolopyridinium compounds and substituted triazaborolopyridinium compounds and methods of use
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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1492929A (fr) * 1966-05-11 1967-08-25 Roussel Uclaf Nouveaux 1-(omega-carboxyalcoyl) indoles substitués et procédé de préparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1492929A (fr) * 1966-05-11 1967-08-25 Roussel Uclaf Nouveaux 1-(omega-carboxyalcoyl) indoles substitués et procédé de préparation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2218098A1 (US06826419-20041130-M00005.png) * 1973-02-16 1974-09-13 Labaz

Also Published As

Publication number Publication date
CH507238A (fr) 1971-05-15
BE728675A (US06826419-20041130-M00005.png) 1969-08-20
US3843683A (en) 1974-10-22
DE1908541A1 (de) 1969-09-18
SE350259B (US06826419-20041130-M00005.png) 1972-10-23
JPS4843740B1 (US06826419-20041130-M00005.png) 1973-12-20
GB1206915A (en) 1970-09-30
US3557142A (en) 1971-01-19
FR2002284B1 (US06826419-20041130-M00005.png) 1973-07-13
NL6902641A (US06826419-20041130-M00005.png) 1969-08-22
BR6906477D0 (pt) 1973-01-16

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Legal Events

Date Code Title Description
ST Notification of lapse