FR15C0005I2 - Composes derives de benzothiazole, compositions et utilisations - Google Patents

Composes derives de benzothiazole, compositions et utilisations

Info

Publication number
FR15C0005I2
FR15C0005I2 FR15C0005C FR15C0005C FR15C0005I2 FR 15C0005 I2 FR15C0005 I2 FR 15C0005I2 FR 15C0005 C FR15C0005 C FR 15C0005C FR 15C0005 C FR15C0005 C FR 15C0005C FR 15C0005 I2 FR15C0005 I2 FR 15C0005I2
Authority
FR
France
Prior art keywords
benzothiazole
compositions
derived compounds
derived
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR15C0005C
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Original Assignee
University of Pittsburgh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/388,173 external-priority patent/US7270800B2/en
Priority claimed from US10/645,847 external-priority patent/US20050043523A1/en
Priority claimed from PCT/US2004/007797 external-priority patent/WO2004083195A1/en
Application filed by University of Pittsburgh filed Critical University of Pittsburgh
Application granted granted Critical
Publication of FR15C0005I2 publication Critical patent/FR15C0005I2/fr
Active legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C07D277/66—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2 with aromatic rings or ring systems directly attached in position 2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FR15C0005C 2003-03-14 2015-01-21 Composes derives de benzothiazole, compositions et utilisations Active FR15C0005I2 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/388,173 US7270800B2 (en) 2000-08-24 2003-03-14 Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US10/645,847 US20050043523A1 (en) 2003-08-22 2003-08-22 Benzothiazole derivative compounds, compositions and uses
PCT/US2004/007797 WO2004083195A1 (en) 2003-03-14 2004-03-15 Benzothiazole derivative compounds, compositions and uses

Publications (1)

Publication Number Publication Date
FR15C0005I2 true FR15C0005I2 (fr) 2015-07-24

Family

ID=35057877

Family Applications (1)

Application Number Title Priority Date Filing Date
FR15C0005C Active FR15C0005I2 (fr) 2003-03-14 2015-01-21 Composes derives de benzothiazole, compositions et utilisations

Country Status (16)

Country Link
EP (1) EP1611115B1 (cs)
JP (1) JP4875487B2 (cs)
CN (2) CN1784392A (cs)
AU (2) AU2004221897B2 (cs)
BE (1) BE2015C005I2 (cs)
BR (1) BRPI0408274B8 (cs)
CY (2) CY1113334T1 (cs)
DK (1) DK1611115T3 (cs)
ES (1) ES2393921T3 (cs)
FR (1) FR15C0005I2 (cs)
HU (1) HUS1500006I1 (cs)
NO (3) NO330861B1 (cs)
PL (1) PL1611115T3 (cs)
PT (1) PT1611115E (cs)
RU (1) RU2440995C2 (cs)
SI (1) SI1611115T1 (cs)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7270800B2 (en) 2000-08-24 2007-09-18 University Of Pittsburgh Thioflavin derivatives for use in antemortem diagnosis of Alzheimer's disease and in vivo imaging and prevention of amyloid deposition
US20020133019A1 (en) * 2000-08-24 2002-09-19 Klunk William E. Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition
CN101198598A (zh) * 2004-05-20 2008-06-11 弗尔德里克斯制药股份有限公司 2-((杂)芳基)-苯并噁唑化合物及其衍生物、组合物以及用于稳定和抑制甲状腺素转运蛋白错重叠的方法
GB0516564D0 (en) * 2005-08-12 2005-09-21 Ge Healthcare Ltd Fluorination process
CN101600973B (zh) * 2007-01-30 2014-05-14 通用电气健康护理有限公司 用于辅助诊断神经退行性疾病的工具
CN101293878B (zh) * 2007-04-25 2010-12-15 中国科学院上海应用物理研究所 苯并噻唑苯胺类化合物及其制备方法和应用
CA2731738A1 (en) * 2008-07-24 2010-01-28 Siemens Medical Solutions Usa, Inc. Imaging agents useful for identifying ad pathology
AU2009295701B2 (en) * 2008-09-23 2014-07-24 Wista Laboratories Ltd. Ligands for aggregated tau molecules
WO2015044095A1 (en) 2013-09-26 2015-04-02 F. Hoffmann-La Roche Ag Imidazo[1,2-a]pyridin-7-amines as imaging tools
JP6260967B2 (ja) * 2013-11-06 2018-01-17 国立大学法人京都大学 放射性ヨウ素標識化合物、及び、これを含む放射性医薬
CN103613589B (zh) * 2013-11-29 2016-03-30 江苏华益科技有限公司 一种用于神经退行性疾病领域的新型pet显像剂前体及标准品的合成方法
MX2017002705A (es) * 2014-08-29 2017-12-20 Chdi Foundation Inc Sondas para la proyección de imagen de la proteína huntingtina.
CN109400615B (zh) * 2017-08-18 2021-07-16 上海交通大学医学院附属新华医院 一种靶向β-淀粉样蛋白的香豆素类化合物及其制备与应用
GR1009516B (el) * 2018-03-22 2019-05-02 Εκεφε Δημοκριτος Τρικαρβονυλο-συμπλοκα μεταλλων μεταπτωσεως με βενζο-ετεροκυκλικο παραγωγο του κυκλοπενταδιενυλικου ανιοντος με υψηλη διαπερατοτητα του αιματοεγκεφαλικου φραγμου για εφαρμογες στη διαγνωση και θεραπεια νοσων του κνς
CN119462558B (zh) * 2024-10-18 2025-09-19 河南中医药大学 一种布美他尼衍生物及其制备方法和用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0942923A2 (en) * 1996-11-22 1999-09-22 Elan Pharmaceuticals, Inc. N-(ARYL/HETEROARYL) AMINO ACID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS
GB9919673D0 (en) * 1999-08-20 1999-10-20 Cancer Res Campaign Tech 2-Arlybenzazole compounds
US20020133019A1 (en) * 2000-08-24 2002-09-19 Klunk William E. Thioflavin derivatives for use in antemortem diagnosis of alzheimer's disease and vivo imaging and prevention of amyloid deposition
WO2002051821A1 (en) * 2000-12-22 2002-07-04 Astrazeneca Ab Therapeutic compounds
AU2002258915B2 (en) * 2001-04-23 2007-11-15 The Trustees Of The University Of Pennsylvania Amyloid plaque aggregation inhibitors and diagnostic imaging agents
GB0229686D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase fluorination of benzothiazoles

Also Published As

Publication number Publication date
EP1611115B1 (en) 2012-08-22
ES2393921T3 (es) 2013-01-02
NO20110980L (no) 2005-12-13
AU2004221897B2 (en) 2010-11-18
NO2015005I1 (no) 2015-03-02
CY1113334T1 (el) 2015-12-09
BRPI0408274A (pt) 2006-03-21
CN102532055B (zh) 2016-05-11
NO2015005I2 (no) 2015-02-18
BRPI0408274B1 (pt) 2019-02-26
SI1611115T1 (sl) 2012-12-31
RU2440995C2 (ru) 2012-01-27
AU2004221897A1 (en) 2004-09-30
PL1611115T3 (pl) 2013-01-31
AU2011200667A1 (en) 2011-03-10
AU2011200667B2 (en) 2011-12-22
BRPI0408274B8 (pt) 2021-05-25
PT1611115E (pt) 2012-12-07
NO20054674L (no) 2005-12-13
AU2004221897A9 (en) 2009-08-20
EP1611115A1 (en) 2006-01-04
CY2015007I1 (el) 2015-12-09
HUS1500006I1 (hu) 2015-02-18
AU2004221897A2 (en) 2004-09-30
CN102532055A (zh) 2012-07-04
JP4875487B2 (ja) 2012-02-15
RU2005131872A (ru) 2006-02-27
DK1611115T3 (da) 2012-11-26
NO20054674D0 (no) 2005-10-11
HK1086270A1 (en) 2006-09-15
JP2006522104A (ja) 2006-09-28
CN1784392A (zh) 2006-06-07
BE2015C005I2 (cs) 2023-03-07
NO330861B1 (no) 2011-08-01

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