FR1551082A - - Google Patents

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Publication number
FR1551082A
FR1551082A FR1551082DA FR1551082A FR 1551082 A FR1551082 A FR 1551082A FR 1551082D A FR1551082D A FR 1551082DA FR 1551082 A FR1551082 A FR 1551082A
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FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Application granted granted Critical
Publication of FR1551082A publication Critical patent/FR1551082A/fr
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
FR1551082D 1966-10-07 1967-10-04 Expired FR1551082A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58495666A 1966-10-07 1966-10-07
US67703667A 1967-10-23 1967-10-23

Publications (1)

Publication Number Publication Date
FR1551082A true FR1551082A (fr) 1968-12-27

Family

ID=27079258

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1551082D Expired FR1551082A (fr) 1966-10-07 1967-10-04

Country Status (4)

Country Link
US (2) US3468882A (fr)
BE (1) BE704777A (fr)
FR (1) FR1551082A (fr)
NL (1) NL6713659A (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0496222A1 (fr) 1991-01-22 1992-07-29 MERCK PATENT GmbH Dérivés de l'indole
FR2672052A1 (fr) * 1991-01-28 1992-07-31 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
AU637991B2 (en) * 1988-12-28 1993-06-17 H. Lundbeck A/S Novel piperazinyl derivatives
EP0645385A1 (fr) * 1993-09-16 1995-03-29 Bristol-Myers Squibb Company Dérivés de cyclobuténediones d'indolylalkylpyridinyl- et -pyrimidinylpipérazines comme agents antimigraines
EP0648767A1 (fr) * 1993-09-30 1995-04-19 MERCK PATENT GmbH Dérivés de piperidine et piperazine qui puissent agir sur le "CNS"
US5521188A (en) * 1993-09-16 1996-05-28 Bristol-Myers Squibb Company Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
EP0729958A2 (fr) * 1995-03-02 1996-09-04 Bristol-Myers Squibb Company Dérivés antimigraines d'indolylpyridinyl et pyrimidinyl-pipérazinyl-1,2,5-thiadiazoles
WO2001049679A1 (fr) * 1999-12-30 2001-07-12 H. Lundbeck A/S Derives de 4-phenyle-1-piperazinyle, -piperidinyle et -tetrahydropyridyle
US6310068B1 (en) 1995-04-05 2001-10-30 Merck Patent Gesellschaft Mit Beschrankter Haftung Benzonitriles and benzofluorides
EA005403B1 (ru) * 2001-07-13 2005-02-24 Ле Лаборатуар Сервье Соединения бензолсульфонамида, способ их получения и фармацевтические композиции их содержащие

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3723464A (en) * 1968-10-25 1973-03-27 Sumitomo Chemical Co Process for manufacturing nitrobenzodiazepine derivatives
FR2190429A1 (en) * 1972-06-28 1974-02-01 Delalande Sa 5-Methoxy-2-methyl-1-phenylindole-3-carboxamides - with analgesic, antiinflammatory, anticonvulsant and other activities
FR2235687A2 (en) * 1973-07-03 1975-01-31 Delalande Sa 1-Trimethoxy phenyl-3-carboxamido indoles - anti-inflammatories, sedatives, vasodilators, hypotensives, analgesics, anticholinergics, anti-ulcer agents etc.
US4145422A (en) * 1977-09-06 1979-03-20 Abbott Laboratories Aminomethylene oxindoles
US4336378A (en) * 1980-04-10 1982-06-22 Sandoz, Inc. Isoxazolyl indolamines
US4336379A (en) * 1980-04-10 1982-06-22 Sandoz, Inc. Isoxazolyl indolamines
US4302589A (en) * 1980-05-08 1981-11-24 American Cyanamid Company Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation
HU196752B (en) * 1983-12-06 1989-01-30 Glaxo Group Ltd Process for production of medical compositions containing indole-derivatives and these compounds
US5380840A (en) * 1985-09-12 1995-01-10 The Upjohn Company Triazinylpiperazinyl steroids
US4954502A (en) * 1988-06-10 1990-09-04 Bristol-Myers Squibb Company 1-indolyalkyl-4-(substituted-pyridinyl)piperazines
DE3923045A1 (de) * 1989-07-13 1991-01-17 Merck Patent Gmbh Indolderivate
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
ES2027898A6 (es) * 1991-01-24 1992-06-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina.
DE4128015A1 (de) * 1991-08-23 1993-02-25 Kali Chemie Pharma Gmbh 1,7-anellierte 2-(piperazinoalkyl)indol-derivate sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindugnen enthaltende arzneimittel
GB9423682D0 (en) * 1994-11-23 1995-01-11 Merck Sharp & Dohme Therapeutic agents
DK1068184T3 (da) * 1998-04-08 2002-12-30 Wyeth Corp N-aryloxyethylaminderivater til behandling af despression
MXPA04012959A (es) * 2002-06-29 2005-05-16 Zentaris Gmbh Arilcarbonilpiperacinas y heteroarilcarbonilpiperacinas y su uso para tratamiento de enfermedades de tumor benigno y maligno.
US8715529B1 (en) 2012-01-23 2014-05-06 Arrowhead Center, Inc. Synthesis and applications of triazaborolopyridinium compounds and substituted triazaborolopyridinium compounds and methods of use

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2708197A (en) * 1952-05-24 1955-05-10 Upjohn Co Preparation of (hydroxy-3-indole)-alkylamines
US3014043A (en) * 1957-02-08 1961-12-19 Merck & Co Inc Serotonin antagonists
GB944443A (fr) * 1959-09-25 1900-01-01
US3364224A (en) * 1961-06-27 1968-01-16 Warner Lambert Pharmaceutical Acylated derivatives of 1, 2, 3, 4-tetrahydro-1-oxo-beta-carbolines
US3218333A (en) * 1962-09-14 1965-11-16 Koninklijke Pharma Fab Nv Aryl indolyl alkenyl amines
US3328407A (en) * 1966-10-07 1967-06-27 Sterling Drug Inc 1-(indolyl lower-alkyl)-4-phenyl-piperazines

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU637991B2 (en) * 1988-12-28 1993-06-17 H. Lundbeck A/S Novel piperazinyl derivatives
US5292739A (en) * 1990-01-28 1994-03-08 Laboratorios Del Dr. Esteve, S.A. Aryl(or heteroaryl) piperazinylalkylazole derivatives, their preparation and their application as medicaments
EP0496222A1 (fr) 1991-01-22 1992-07-29 MERCK PATENT GmbH Dérivés de l'indole
FR2672052A1 (fr) * 1991-01-28 1992-07-31 Esteve Labor Dr Derives d'aryl (ou heteroaryl)-piperazinyl-alkyl-azoles, leur preparation et leur application en tant que medicaments.
US5382586A (en) * 1991-01-28 1995-01-17 Laboratorios Del Dr. Esteve S.A. Aryl (or heteroaryl)piperazinylalkylazole derivatives, their preparation and their application as medicaments
EP0645385A1 (fr) * 1993-09-16 1995-03-29 Bristol-Myers Squibb Company Dérivés de cyclobuténediones d'indolylalkylpyridinyl- et -pyrimidinylpipérazines comme agents antimigraines
US5521188A (en) * 1993-09-16 1996-05-28 Bristol-Myers Squibb Company Antimigraine cyclobutenedione derivatives of indolylalkyl-pyridinyl and pyrimidinylpiperazines
EP0648767A1 (fr) * 1993-09-30 1995-04-19 MERCK PATENT GmbH Dérivés de piperidine et piperazine qui puissent agir sur le "CNS"
EP0729958A2 (fr) * 1995-03-02 1996-09-04 Bristol-Myers Squibb Company Dérivés antimigraines d'indolylpyridinyl et pyrimidinyl-pipérazinyl-1,2,5-thiadiazoles
EP0729958A3 (fr) * 1995-03-02 1996-10-02 Bristol Myers Squibb Co
US6310068B1 (en) 1995-04-05 2001-10-30 Merck Patent Gesellschaft Mit Beschrankter Haftung Benzonitriles and benzofluorides
WO2001049679A1 (fr) * 1999-12-30 2001-07-12 H. Lundbeck A/S Derives de 4-phenyle-1-piperazinyle, -piperidinyle et -tetrahydropyridyle
JP2003519225A (ja) * 1999-12-30 2003-06-17 ハー・ルンドベック・アクチエゼルスカベット ４−フェニル−１−ピペラジニル、−ピペリジニル、および−テトラヒドロピリジル誘導体
US7074796B2 (en) 1999-12-30 2006-07-11 H. Lundbeck A/S 4-phenyl-1-piperazinyl, -piperidinyl and -tetrahydropyridyl derivatives
US7223765B2 (en) 1999-12-30 2007-05-29 H. Lundbeck A/S 4-phenyl-1-piperazinyl, -piperidinyl and -tetrahydropyridyl derivatives
EA008627B1 (ru) * 1999-12-30 2007-06-29 Х. Лундбекк А/С Замещенные галогеном производные 4-фенил-1-пиперазинила, их применение и содержащая их фармацевтическая композиция
EA005403B1 (ru) * 2001-07-13 2005-02-24 Ле Лаборатуар Сервье Соединения бензолсульфонамида, способ их получения и фармацевтические композиции их содержащие

Also Published As

Publication number Publication date
US3468882A (en) 1969-09-23
NL6713659A (fr) 1968-04-08
US3466287A (en) 1969-09-09
BE704777A (fr) 1968-04-08

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ST Notification of lapse