FI991441A - Peptidiyhdisteitä erityisesti LHRH-antagonisteja - Google Patents
Peptidiyhdisteitä erityisesti LHRH-antagonisteja Download PDFInfo
- Publication number
- FI991441A FI991441A FI991441A FI991441A FI991441A FI 991441 A FI991441 A FI 991441A FI 991441 A FI991441 A FI 991441A FI 991441 A FI991441 A FI 991441A FI 991441 A FI991441 A FI 991441A
- Authority
- FI
- Finland
- Prior art keywords
- neu
- pct
- lhrh antagonists
- date
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Endocrinology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4117507A DE4117507A1 (de) | 1991-05-24 | 1991-05-24 | Verfahren zur herstellung von n(pfeil hoch)6(pfeil hoch)-substituierten lysin-derivaten |
| DE4117507 | 1991-05-24 | ||
| DE9200427 | 1992-05-22 | ||
| PCT/DE1992/000427 WO1992020711A2 (de) | 1991-05-24 | 1992-05-22 | Lhrh-antagonisten und zwischenprodukte |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI991441A0 FI991441A0 (fi) | 1999-06-24 |
| FI991441A true FI991441A (fi) | 1999-06-24 |
| FI114026B FI114026B (fi) | 2004-07-30 |
Family
ID=6432667
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI935191A FI105817B (fi) | 1991-05-24 | 1993-11-23 | Menetelmä terapeuttisesti käyttökelpoisten peptidiyhdisteiden valmistamiseksi |
| FI991441A FI114026B (fi) | 1991-05-24 | 1999-06-24 | Peptidiyhdisteitä erityisesti LHRH-antagonisteja, joita käytetään hedelmällisyyden kontrollointiin |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI935191A FI105817B (fi) | 1991-05-24 | 1993-11-23 | Menetelmä terapeuttisesti käyttökelpoisten peptidiyhdisteiden valmistamiseksi |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5527777A (fi) |
| EP (1) | EP0668874B1 (fi) |
| JP (1) | JP3370668B2 (fi) |
| AT (1) | ATE170190T1 (fi) |
| AU (1) | AU667038B2 (fi) |
| CA (1) | CA2109830C (fi) |
| DE (3) | DE4117507A1 (fi) |
| DK (1) | DK0668874T3 (fi) |
| ES (1) | ES2123554T3 (fi) |
| FI (2) | FI105817B (fi) |
| HU (1) | HU219912B (fi) |
| NO (1) | NO311725B1 (fi) |
| RU (1) | RU2124023C1 (fi) |
| WO (1) | WO1992020711A2 (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801577A (en) * | 1987-02-05 | 1989-01-31 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists |
| US5843901A (en) * | 1995-06-07 | 1998-12-01 | Advanced Research & Technology Institute | LHRH antagonist peptides |
| US5916582A (en) * | 1996-07-03 | 1999-06-29 | Alza Corporation | Aqueous formulations of peptides |
| US5932547A (en) | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
| US5981489A (en) * | 1996-07-18 | 1999-11-09 | Alza Corporation | Non-aqueous protic peptide formulations |
| US6455499B1 (en) | 1999-02-23 | 2002-09-24 | Indiana University Foundation | Methods for treating disorders associated with LHRH activity |
| DE19911771B4 (de) * | 1999-03-17 | 2006-03-30 | Zentaris Gmbh | LHRH-Antagonist, Verfahren zu seiner Herstellung und seiner Verwendung |
| GB201009603D0 (en) * | 2010-06-08 | 2010-07-21 | Cambridge Entpr Ltd | Anti-inflammatory agent |
| AR122446A1 (es) * | 2020-04-29 | 2022-09-14 | Medimmune Llc | Composiciones y métodos para suministrar agentes farmacéuticamente activos |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4667014A (en) * | 1983-03-07 | 1987-05-19 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH, useful as LHRH antagonists |
| US4801577A (en) * | 1987-02-05 | 1989-01-31 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide analogs of LHRH useful as LHRH antagonists |
| US4800191A (en) * | 1987-07-17 | 1989-01-24 | Schally Andrew Victor | LHRH antagonists |
| US4935491A (en) * | 1987-08-24 | 1990-06-19 | Board Of Regents, The University Of Texas System | Effective antagonists of the luteinizing hormone releasing hormone which release negligible histamine |
| IE902446A1 (en) * | 1989-07-26 | 1991-02-13 | Abbott Lab | Peptidyl aminodiol renin inhibitors |
-
1991
- 1991-05-24 DE DE4117507A patent/DE4117507A1/de not_active Withdrawn
-
1992
- 1992-05-22 AT AT92910746T patent/ATE170190T1/de not_active IP Right Cessation
- 1992-05-22 DE DE59209476T patent/DE59209476D1/de not_active Expired - Lifetime
- 1992-05-22 DE DEDE9200427T patent/DE4291426D2/de not_active Expired - Lifetime
- 1992-05-22 US US08/142,429 patent/US5527777A/en not_active Expired - Fee Related
- 1992-05-22 AU AU18879/92A patent/AU667038B2/en not_active Ceased
- 1992-05-22 HU HU9303324A patent/HU219912B/hu not_active IP Right Cessation
- 1992-05-22 ES ES92910746T patent/ES2123554T3/es not_active Expired - Lifetime
- 1992-05-22 DK DK92910746T patent/DK0668874T3/da active
- 1992-05-22 CA CA002109830A patent/CA2109830C/en not_active Expired - Fee Related
- 1992-05-22 EP EP92910746A patent/EP0668874B1/de not_active Expired - Lifetime
- 1992-05-22 WO PCT/DE1992/000427 patent/WO1992020711A2/de active IP Right Grant
- 1992-05-22 JP JP50975692A patent/JP3370668B2/ja not_active Expired - Fee Related
- 1992-05-22 RU RU93058365A patent/RU2124023C1/ru not_active IP Right Cessation
-
1993
- 1993-11-23 FI FI935191A patent/FI105817B/fi not_active IP Right Cessation
- 1993-11-23 NO NO19934237A patent/NO311725B1/no unknown
-
1999
- 1999-06-24 FI FI991441A patent/FI114026B/fi not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE4291426D2 (de) | 1994-02-17 |
| FI935191A (fi) | 1993-11-23 |
| EP0668874B1 (de) | 1998-08-26 |
| NO311725B1 (no) | 2002-01-14 |
| FI991441A0 (fi) | 1999-06-24 |
| DE4117507A1 (de) | 1992-11-26 |
| WO1992020711A3 (de) | 1993-03-18 |
| CA2109830A1 (en) | 1992-11-26 |
| FI114026B (fi) | 2004-07-30 |
| WO1992020711A2 (de) | 1992-11-26 |
| DE59209476D1 (de) | 1998-10-01 |
| CA2109830C (en) | 2003-04-08 |
| JPH06508115A (ja) | 1994-09-14 |
| NO934237D0 (no) | 1993-11-23 |
| HUT65732A (en) | 1994-07-28 |
| ATE170190T1 (de) | 1998-09-15 |
| AU1887992A (en) | 1992-12-30 |
| FI105817B (fi) | 2000-10-13 |
| RU2124023C1 (ru) | 1998-12-27 |
| HU9303324D0 (en) | 1994-03-28 |
| DK0668874T3 (da) | 1999-05-25 |
| US5527777A (en) | 1996-06-18 |
| EP0668874A1 (de) | 1995-08-30 |
| AU667038B2 (en) | 1996-03-07 |
| ES2123554T3 (es) | 1999-01-16 |
| HU219912B (hu) | 2001-09-28 |
| JP3370668B2 (ja) | 2003-01-27 |
| NO934237L (no) | 1993-11-23 |
| FI935191A0 (fi) | 1993-11-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GT199800126A (es) | Terapia de combinacion. | |
| ATE215081T1 (de) | Gonadotropin releasing hormon- antagonisten | |
| DE69311556D1 (de) | Inhalationspulver enthaltend antistatisches hilfsmittel | |
| ES2136723T3 (es) | Utilizacion de n-aril-metilen-etilen-diamino-triacetatos, n-aril-metilen-imino-diacetatos o n,n'-diaril-metilen-etilen-diamino-acetatos contra el estres oxidante. | |
| TR200001603T2 (tr) | Yeni bileşikler | |
| DK0728148T3 (da) | Forbedrede immunogene sammensætninger mod humant gastrin 17 | |
| DE69326250D1 (de) | Neuropeptide y antagoniste | |
| ES2131528T3 (es) | Nuevos polipeptidos y su uso. | |
| EP0646007A1 (en) | NEW DELTA-17 AND DELTA-20 UNSATURATED AND SATURATED 17 - g (b) -SUBSTITUTED-4-AZA-5-g (a) -ANDROSTAN-3-ON COMPOUNDS AS INHIBITORS OF 5-ALPHA REDUCTASE. | |
| FI991441A0 (fi) | Peptidiyhdisteitä erityisesti LHRH-antagonisteja | |
| DE69006214D1 (de) | Gesteuerte zerstreuung des eingespritzten brennstoffes. | |
| FR2694296B1 (fr) | Peptides inhibant l'activité des protéines ras, préparation et utilisation. | |
| BG103677A (en) | Solid mixtures based on sulphonylcarbamides and adjuvants | |
| SE9402880D0 (sv) | New peptide derivatives | |
| GB9515279D0 (en) | Improved therapeutic agents | |
| RU93058365A (ru) | Пептидные соединения и содержащее их лекарственное средство | |
| KR950702234A (ko) | 첨가제 및 연료 조성물(additives and fuel compositions). | |
| IT1258305B (it) | Composizioni farmaceutiche rettali per il trattamento dell'ipertrofia prostatica | |
| JPS5572153A (en) | Undecapeptide | |
| IT219198Z2 (it) | Dispositivo di raccordo perfezionato per l'alimentazione di un iniettore. | |
| NZ510253A (en) | Neuroprotection | |
| GR1001368B (el) | Φαρμακευτικοί φορείς. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |