FI972720A - Förfarande för framställning av lamotrigin - Google Patents
Förfarande för framställning av lamotrigin Download PDFInfo
- Publication number
- FI972720A FI972720A FI972720A FI972720A FI972720A FI 972720 A FI972720 A FI 972720A FI 972720 A FI972720 A FI 972720A FI 972720 A FI972720 A FI 972720A FI 972720 A FI972720 A FI 972720A
- Authority
- FI
- Finland
- Prior art keywords
- preparing lamotrigine
- lamotrigine
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9426448.8A GB9426448D0 (en) | 1994-12-30 | 1994-12-30 | Process |
| PCT/GB1995/003049 WO1996020935A1 (en) | 1994-12-30 | 1995-12-29 | Process for the preparation of lamotrigine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI972720A0 FI972720A0 (sv) | 1997-06-24 |
| FI972720A true FI972720A (sv) | 1997-08-27 |
Family
ID=10766744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI972720A FI972720A (sv) | 1994-12-30 | 1997-06-24 | Förfarande för framställning av lamotrigin |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5925755A (sv) |
| EP (1) | EP0800521A1 (sv) |
| JP (1) | JPH11507011A (sv) |
| AU (1) | AU4311696A (sv) |
| FI (1) | FI972720A (sv) |
| GB (1) | GB9426448D0 (sv) |
| HU (1) | HUT77347A (sv) |
| RU (1) | RU2162081C2 (sv) |
| WO (1) | WO1996020935A1 (sv) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9512854D0 (en) * | 1995-06-23 | 1995-08-23 | Wellcome Found | Novel formulation |
| GB9726987D0 (en) * | 1997-12-22 | 1998-02-18 | Glaxo Group Ltd | Compounds |
| US6420354B1 (en) | 1998-06-08 | 2002-07-16 | Advanced Medicine, Inc. | Sodium channel drugs and uses |
| GB9812413D0 (en) * | 1998-06-10 | 1998-08-05 | Glaxo Group Ltd | Compound and its use |
| US6479498B1 (en) | 1999-06-04 | 2002-11-12 | Theravance, Inc. | Sodium channel drugs and uses |
| AU763244B2 (en) * | 2000-01-03 | 2003-07-17 | Rpg Life Sciences Limited | A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine |
| WO2002068398A1 (en) * | 2001-02-27 | 2002-09-06 | Teva Pharmaceutical Industries Ltd. | New crystal forms of lamotrigine and processes for their preparations |
| US7265137B2 (en) | 2001-08-10 | 2007-09-04 | Nippon Chemiphar Co., Ltd. | Activator of peroxisome proliferator-activated re-ceptor δ |
| JP4276074B2 (ja) | 2001-10-12 | 2009-06-10 | 日本ケミファ株式会社 | ペルオキシソーム増殖剤応答性受容体δの活性化剤 |
| CA2366521C (en) | 2001-12-24 | 2007-03-06 | Brantford Chemicals Inc. | A new and efficient process for the preparation of lamotrigine and related 3,5-diamino-6-substituted-1,2,4-triazines |
| WO2003090693A2 (en) * | 2002-04-23 | 2003-11-06 | Teva Pharmaceutical Industries Ltd. | Pharmaceutical composition containing lamotrigine particles of defined morphology |
| HU225667B1 (en) | 2002-09-20 | 2007-05-29 | Richter Gedeon Nyrt | Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine |
| CN102643248A (zh) | 2006-04-18 | 2012-08-22 | 日本化学医药株式会社 | 过氧化物酶体增殖剂激活受体δ的激活剂 |
| US20120142919A1 (en) | 2006-08-02 | 2012-06-07 | Medichem, S.A. | Method for synthesizing lamotrigine |
| US8486927B2 (en) * | 2007-11-09 | 2013-07-16 | Thar Pharmaceuticals | Crystalline forms of lamotrigine |
| CN102083810B (zh) | 2008-04-15 | 2014-10-29 | 日本化学医药株式会社 | 过氧化物酶体增殖剂活化受体的活化剂 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK153787C (da) * | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
-
1994
- 1994-12-30 GB GBGB9426448.8A patent/GB9426448D0/en active Pending
-
1995
- 1995-12-29 AU AU43116/96A patent/AU4311696A/en not_active Abandoned
- 1995-12-29 RU RU97112921/04A patent/RU2162081C2/ru not_active IP Right Cessation
- 1995-12-29 US US08/836,152 patent/US5925755A/en not_active Expired - Fee Related
- 1995-12-29 JP JP8520618A patent/JPH11507011A/ja not_active Withdrawn
- 1995-12-29 EP EP95941818A patent/EP0800521A1/en not_active Withdrawn
- 1995-12-29 WO PCT/GB1995/003049 patent/WO1996020935A1/en not_active Application Discontinuation
- 1995-12-29 HU HU9701875A patent/HUT77347A/hu not_active Application Discontinuation
-
1997
- 1997-06-24 FI FI972720A patent/FI972720A/sv not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH11507011A (ja) | 1999-06-22 |
| HUT77347A (hu) | 1998-03-30 |
| WO1996020935A1 (en) | 1996-07-11 |
| RU2162081C2 (ru) | 2001-01-20 |
| US5925755A (en) | 1999-07-20 |
| EP0800521A1 (en) | 1997-10-15 |
| AU4311696A (en) | 1996-07-24 |
| FI972720A0 (sv) | 1997-06-24 |
| GB9426448D0 (en) | 1995-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |