FI972720A0 - Förfarande för framställning av lamotrigin - Google Patents

Förfarande för framställning av lamotrigin

Info

Publication number
FI972720A0
FI972720A0 FI972720A FI972720A FI972720A0 FI 972720 A0 FI972720 A0 FI 972720A0 FI 972720 A FI972720 A FI 972720A FI 972720 A FI972720 A FI 972720A FI 972720 A0 FI972720 A0 FI 972720A0
Authority
FI
Finland
Prior art keywords
preparing lamotrigine
lamotrigine
preparing
Prior art date
Application number
FI972720A
Other languages
English (en)
Finnish (fi)
Other versions
FI972720A (sv
Inventor
Grahame Roy Lee
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI972720A0 publication Critical patent/FI972720A0/sv
Publication of FI972720A publication Critical patent/FI972720A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D253/075—Two hetero atoms, in positions 3 and 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
    • C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI972720A 1994-12-30 1997-06-24 Förfarande för framställning av lamotrigin FI972720A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9426448.8A GB9426448D0 (en) 1994-12-30 1994-12-30 Process
PCT/GB1995/003049 WO1996020935A1 (en) 1994-12-30 1995-12-29 Process for the preparation of lamotrigine

Publications (2)

Publication Number Publication Date
FI972720A0 true FI972720A0 (sv) 1997-06-24
FI972720A FI972720A (sv) 1997-08-27

Family

ID=10766744

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972720A FI972720A (sv) 1994-12-30 1997-06-24 Förfarande för framställning av lamotrigin

Country Status (9)

Country Link
US (1) US5925755A (sv)
EP (1) EP0800521A1 (sv)
JP (1) JPH11507011A (sv)
AU (1) AU4311696A (sv)
FI (1) FI972720A (sv)
GB (1) GB9426448D0 (sv)
HU (1) HUT77347A (sv)
RU (1) RU2162081C2 (sv)
WO (1) WO1996020935A1 (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9512854D0 (en) * 1995-06-23 1995-08-23 Wellcome Found Novel formulation
GB9726987D0 (en) 1997-12-22 1998-02-18 Glaxo Group Ltd Compounds
US6420354B1 (en) 1998-06-08 2002-07-16 Advanced Medicine, Inc. Sodium channel drugs and uses
GB9812413D0 (en) * 1998-06-10 1998-08-05 Glaxo Group Ltd Compound and its use
US6479498B1 (en) 1999-06-04 2002-11-12 Theravance, Inc. Sodium channel drugs and uses
AU763244B2 (en) * 2000-01-03 2003-07-17 Rpg Life Sciences Limited A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine
EP1390355A4 (en) * 2001-02-27 2005-02-23 Teva Pharma NEW CRYSTALLINE FORMS OF LAMOTRIGIN AND METHOD FOR THE PRODUCTION THEREOF
CA2457054C (en) 2001-08-10 2011-10-11 Nippon Chemiphar Co., Ltd. Activator of peroxisome proliferator-activated receptor .delta.
AU2002335231B2 (en) 2001-10-12 2008-05-08 Nippon Chemiphar Co., Ltd. Activator for peroxisome proliferator-activated receptor delta
CA2366521C (en) 2001-12-24 2007-03-06 Brantford Chemicals Inc. A new and efficient process for the preparation of lamotrigine and related 3,5-diamino-6-substituted-1,2,4-triazines
ATE357217T1 (de) * 2002-04-23 2007-04-15 Teva Pharma Pharmazeutische zusammensetzung enthaltend lamotrigine-partikel mit definierter morphologie
HU225667B1 (en) 2002-09-20 2007-05-29 Richter Gedeon Nyrt Method for producing high-purity 3,5-diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine
BRPI0710266B8 (pt) 2006-04-18 2021-05-25 Nippon Chemiphar Co composto, medicamento, e, uso de um composto
US20120142919A1 (en) 2006-08-02 2012-06-07 Medichem, S.A. Method for synthesizing lamotrigine
US8486927B2 (en) * 2007-11-09 2013-07-16 Thar Pharmaceuticals Crystalline forms of lamotrigine
KR101710340B1 (ko) 2008-04-15 2017-02-27 닛뽕 케미파 가부시키가이샤 퍼옥시좀 증식제 활성화 수용체의 활성화제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS234018B2 (en) * 1979-06-01 1985-03-14 Wellcome Found Method of 3,5-diammino-6-1,2,4-triazine derivatives making

Also Published As

Publication number Publication date
AU4311696A (en) 1996-07-24
US5925755A (en) 1999-07-20
JPH11507011A (ja) 1999-06-22
FI972720A (sv) 1997-08-27
GB9426448D0 (en) 1995-03-01
WO1996020935A1 (en) 1996-07-11
HUT77347A (hu) 1998-03-30
RU2162081C2 (ru) 2001-01-20
EP0800521A1 (en) 1997-10-15

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Legal Events

Date Code Title Description
FD Application lapsed