FI964267A - Porfosyaniini ja CNC-laajennetut porfyriinit - Google Patents

Porfosyaniini ja CNC-laajennetut porfyriinit Download PDF

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Publication number
FI964267A
FI964267A FI964267A FI964267A FI964267A FI 964267 A FI964267 A FI 964267A FI 964267 A FI964267 A FI 964267A FI 964267 A FI964267 A FI 964267A FI 964267 A FI964267 A FI 964267A
Authority
FI
Finland
Prior art keywords
porphocyanin
cnc
extended porphyrins
porphyrins
extended
Prior art date
Application number
FI964267A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI964267A0 (fi
Inventor
Ross W Boyle
Hang Tang
Lily Xie
Tilak Wijesekera
David Dolphin
Original Assignee
Quadra Logic Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quadra Logic Tech Inc filed Critical Quadra Logic Tech Inc
Publication of FI964267A0 publication Critical patent/FI964267A0/fi
Publication of FI964267A publication Critical patent/FI964267A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0485—Porphyrins, texaphyrins wherein the nitrogen atoms forming the central ring system complex the radioactive metal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0076—PDT with expanded (metallo)porphyrins, i.e. having more than 20 ring atoms, e.g. texaphyrins, sapphyrins, hexaphyrins, pentaphyrins, porphocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/002—Heterocyclic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/004—Acyclic, carbocyclic or heterocyclic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur, selenium or tellurium
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biochemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI964267A 1994-04-26 1996-10-23 Porfosyaniini ja CNC-laajennetut porfyriinit FI964267A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/233,632 US5726304A (en) 1992-10-30 1994-04-26 Porphocyanine and CNC-expanded porphyrins
PCT/CA1995/000242 WO1995029180A1 (en) 1994-04-26 1995-04-26 Porphocyanine and cnc-expanded porphyrins

Publications (2)

Publication Number Publication Date
FI964267A0 FI964267A0 (fi) 1996-10-23
FI964267A true FI964267A (fi) 1996-12-19

Family

ID=22878063

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964267A FI964267A (fi) 1994-04-26 1996-10-23 Porfosyaniini ja CNC-laajennetut porfyriinit

Country Status (13)

Country Link
US (1) US5726304A (no)
EP (1) EP0757689A1 (no)
JP (1) JPH10500942A (no)
KR (1) KR100241853B1 (no)
AU (1) AU697139B2 (no)
CA (1) CA2188029C (no)
CZ (1) CZ288186B6 (no)
FI (1) FI964267A (no)
HU (1) HUT77405A (no)
NO (1) NO309481B1 (no)
NZ (1) NZ284413A (no)
PL (1) PL317024A1 (no)
WO (1) WO1995029180A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2206203A1 (en) * 1997-05-27 1998-11-27 University Of British Columbia Photoactivation of endogenous porphyrins for treatment of psoriasis
WO2000061584A1 (en) 1999-04-14 2000-10-19 The University Of British Columbia IMPROVED β,β,-DIHYDROXY MESO-SUBSTITUTED CHLORINS, ISOBACTERIOCHLORINS, AND BACTERIOCHLORINS
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
CN1626246A (zh) 1999-07-29 2005-06-15 埃匹克斯医药品股份有限公司 通过多位点结合的寻靶多体造影剂
AU2001258095A1 (en) * 2000-05-08 2001-11-20 The University Of British Columbia Drug delivery systems for photodynamic therapy
WO2001085213A2 (en) 2000-05-08 2001-11-15 The University Of British Columbia Supports for photosensitizer formulations
TWI221406B (en) 2001-07-30 2004-10-01 Epix Medical Inc Systems and methods for targeted magnetic resonance imaging of the vascular system
US20120034155A1 (en) * 2010-08-03 2012-02-09 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Artificial cells
JP5988584B2 (ja) 2008-12-16 2016-09-07 キュー エル ティー インク．ＱＬＴ Ｉｎｃ． 眼の状態に関する光線力学的療法
CN102844044B (zh) 2010-02-04 2016-10-26 摩尔弗泰克有限公司 氯毒素多肽和结合物及其应用
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
JP6181059B2 (ja) 2011-10-25 2017-08-16 メモリアル スローン−ケタリング キャンサー センター 前立腺がんのための診断薬、予後判定薬、および治療薬としてのフリーｐｓａ抗体
EP2911666B1 (en) 2012-10-26 2022-08-24 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
ES2741811T3 (es) 2013-12-23 2020-02-12 Memorial Sloan Kettering Cancer Center Métodos y composiciones para el tratamiento del cáncer utilizando agentes peptidos a base de ácido nucleico

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935498A (en) * 1989-03-06 1990-06-19 Board Of Regents, The University Of Texas System Expanded porphyrins: large porphyrin-like tripyrroledimethine-derived macrocycles
US5405957A (en) * 1992-10-30 1995-04-11 The University Of British Columbia Wavelength-specific photosensitive compounds and expanded porphyrin-like compounds and methods of use

Also Published As

Publication number Publication date
NO964541L (no) 1996-12-23
NO964541D0 (no) 1996-10-25
CZ288186B6 (en) 2001-05-16
HUT77405A (hu) 1998-04-28
NO309481B1 (no) 2001-02-05
KR970702861A (ko) 1997-06-10
EP0757689A1 (en) 1997-02-12
AU2300795A (en) 1995-11-16
AU697139B2 (en) 1998-09-24
US5726304A (en) 1998-03-10
CA2188029C (en) 2008-07-08
KR100241853B1 (ko) 2000-03-02
CA2188029A1 (en) 1995-11-02
JPH10500942A (ja) 1998-01-27
HU9602956D0 (en) 1997-01-28
WO1995029180A1 (en) 1995-11-02
NZ284413A (en) 1998-08-26
PL317024A1 (en) 1997-03-03
FI964267A0 (fi) 1996-10-23
CZ314296A3 (en) 1997-05-14

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