FI962496A7 - 3-substituoidut 1-aryyli-indoliyhdisteet - Google Patents

3-substituoidut 1-aryyli-indoliyhdisteet Download PDF

Info

Publication number
FI962496A7
FI962496A7 FI962496A FI962496A FI962496A7 FI 962496 A7 FI962496 A7 FI 962496A7 FI 962496 A FI962496 A FI 962496A FI 962496 A FI962496 A FI 962496A FI 962496 A7 FI962496 A7 FI 962496A7
Authority
FI
Finland
Prior art keywords
substituted
indole compounds
aryl indole
aryl
compounds
Prior art date
Application number
FI962496A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI962496A0 (fi
Inventor
Kim Andersen
Jens Kristian Perregaard
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of FI962496A7 publication Critical patent/FI962496A7/fi
Publication of FI962496A0 publication Critical patent/FI962496A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/36—Oxygen atoms in position 3, e.g. adrenochrome

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI962496A 1993-12-16 1996-06-14 3-substituoidut 1-aryyli-indoliyhdisteet FI962496A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK931395A DK139593D0 (da) 1993-12-16 1993-12-16 Compounds
PCT/DK1994/000470 WO1995016684A1 (en) 1993-12-16 1994-12-15 3-substituted 1-arylindole compounds

Publications (2)

Publication Number Publication Date
FI962496A7 true FI962496A7 (fi) 1996-06-14
FI962496A0 FI962496A0 (fi) 1996-06-14

Family

ID=8104386

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962496A FI962496A0 (fi) 1993-12-16 1996-06-14 3-substituoidut 1-aryyli-indoliyhdisteet

Country Status (24)

Country Link
US (1) US5789404A (cs)
EP (2) EP0734384B1 (cs)
JP (1) JPH09506595A (cs)
KR (1) KR100363484B1 (cs)
CN (1) CN1080261C (cs)
AT (1) ATE195313T1 (cs)
AU (1) AU682915B2 (cs)
CA (1) CA2179179A1 (cs)
CZ (1) CZ285028B6 (cs)
DE (1) DE69425510T2 (cs)
DK (2) DK139593D0 (cs)
ES (1) ES2149959T3 (cs)
FI (1) FI962496A0 (cs)
GR (1) GR3034744T3 (cs)
HU (1) HU223318B1 (cs)
IL (1) IL111989A (cs)
NO (1) NO306671B1 (cs)
NZ (1) NZ277483A (cs)
PL (1) PL181253B1 (cs)
PT (1) PT734384E (cs)
RU (1) RU2139287C1 (cs)
SK (1) SK283451B6 (cs)
WO (1) WO1995016684A1 (cs)
ZA (1) ZA949918B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0775131A2 (de) * 1994-08-03 1997-05-28 ASTA Medica Aktiengesellschaft Indol-, indazol-, pyridopyrrol- und pyridopyrazol-derivate mit antiasthmatischer, antiallergischer, entzündungshemmender und immunmodulierender wirkung
MY125942A (en) * 1999-09-07 2006-09-29 Upjohn Co Aminoalkoxy carbazoles for the treatment of cns diseases
RU2337906C2 (ru) * 2001-12-03 2008-11-10 Уайт Ингибиторы цитозольной фосфолипазы а2
US7297711B2 (en) * 2002-06-21 2007-11-20 Suven Life Sciences Limited Arylalkyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
US7317035B2 (en) * 2002-06-21 2008-01-08 Suven Life Sciences Limited Tetracyclic arylcarbonyl indoles having serotonin receptor affinity useful as therapeutic agents, process for their preparation and pharmaceutical compositions containing them
ATE462692T1 (de) * 2004-06-01 2010-04-15 Hoffmann La Roche 3-amino-1-arylpropyl-indole als monoamin- wiederaufnahmehemmer
AU2007254179B2 (en) 2006-05-18 2013-03-21 Pharmacyclics Llc Intracellular kinase inhibitors

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1220628A (en) * 1968-07-20 1971-01-27 Pfizer Ltd N-phenyl indole derivatives and pharmaceutical compositions thereof
GB1237008A (en) * 1968-12-18 1971-06-30 Pfizer Ltd Novel indoline derivatives
DE1911893A1 (de) * 1969-03-08 1970-09-24 Thiemann Gmbh Chem Pharm Fabri Verfahren zur Herstellung von N-(Halogen-aryl)-2-methyl-5-alkoxy-indol-3-essigsaeuren
SU373940A3 (cs) * 1970-01-21 1973-03-12
BE795457A (fr) * 1972-02-16 1973-08-16 Clin Midy Amines indoliques, leur preparation et leur application en therapeutiques
FR2242091A1 (en) * 1973-09-04 1975-03-28 Delalande Sa 1-Phenyl-2-methyl-3-aminomethyl-5-methoxy indole derivs - with e.g. analgesic, antidepressive and anti-arrhythmic props
US4558048A (en) * 1984-04-06 1985-12-10 Pfizer Inc. Method of treating diarrhoea using indole compounds
DE3430284A1 (de) * 1984-08-17 1986-02-27 Troponwerke GmbH & Co KG, 5000 Köln Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung
SE8701375D0 (sv) * 1987-04-02 1987-04-02 Leo Ab Novel pyridyl- and pyrimidyl derivatives
DK152090D0 (da) * 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater
DK158590D0 (da) * 1990-07-02 1990-07-02 Lundbeck & Co As H Indolderivater
DK36391D0 (da) * 1991-03-01 1991-03-01 Lundbeck & Co As H Anvendelse af piperidylsubstituerede indolderivater til behandling af stofmisbrug
FR2701026B1 (fr) * 1993-02-02 1995-03-31 Adir Nouveaux dérivés de l'indole, de l'indazole et du benzisoxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2705346B1 (fr) * 1993-05-18 1995-08-11 Union Pharma Scient Appl Nouveaux dérivés de pipéridinyl thio indole, leurs procédés de préparation, compositions pharmaceutiques les contenant, utiles notamment comme antalgiques .
US5504101A (en) * 1994-05-06 1996-04-02 Allelix Biopharmaceuticals, Inc. 5-HT-1D receptor ligands

Also Published As

Publication number Publication date
GR3034744T3 (en) 2001-02-28
HK1013815A1 (en) 1999-09-10
PL315027A1 (en) 1996-09-30
IL111989A (en) 2000-10-31
IL111989A0 (en) 1995-03-15
DE69425510D1 (de) 2000-09-14
CN1142824A (zh) 1997-02-12
CZ285028B6 (cs) 1999-05-12
SK75896A3 (en) 1996-11-06
NO962505D0 (no) 1996-06-13
PL181253B1 (pl) 2001-06-29
PT734384E (pt) 2000-12-29
EP0939077A3 (en) 2003-11-19
HU223318B1 (hu) 2004-05-28
DK0734384T3 (da) 2001-01-02
AU682915B2 (en) 1997-10-23
KR100363484B1 (ko) 2003-02-05
WO1995016684A1 (en) 1995-06-22
DE69425510T2 (de) 2001-04-19
NZ277483A (en) 1998-05-27
EP0939077A2 (en) 1999-09-01
KR960706492A (ko) 1996-12-09
RU2139287C1 (ru) 1999-10-10
AU1272195A (en) 1995-07-03
NO306671B1 (no) 1999-12-06
ES2149959T3 (es) 2000-11-16
ATE195313T1 (de) 2000-08-15
CN1080261C (zh) 2002-03-06
US5789404A (en) 1998-08-04
EP0734384A1 (en) 1996-10-02
HU9601640D0 (en) 1996-08-28
CZ172796A3 (en) 1996-11-13
CA2179179A1 (en) 1995-06-22
SK283451B6 (sk) 2003-08-05
NO962505L (no) 1996-08-12
EP0734384B1 (en) 2000-08-09
ZA949918B (en) 1995-08-23
DK139593D0 (da) 1993-12-16
HUT76276A (en) 1997-07-28
JPH09506595A (ja) 1997-06-30
FI962496A0 (fi) 1996-06-14

Similar Documents

Publication Publication Date Title
FI944969A0 (fi) Indolijohdannaisia
FI945555L (fi) Substituoituja oksindoleja
NO943913D0 (no) Indol-derivater
NO961475L (no) Indol-derivater
FI972275L (fi) Indolijohdannainen
ZA941483B (en) Indole derivatives
MX9205306A (es) 3-feniluracilos sustituidos
FI933697A7 (fi) 3-Piperidinyylimetyylikarboksylaattisubstituoidut indolit
GB9319297D0 (en) Indole derivatives
GB9326332D0 (en) Indole derivatives
ZA942805B (en) Indole derivatives
NO940237L (no) Indoler
FI961844L (fi) Fenyyli-indoliyhdisteitä
FI962496A7 (fi) 3-substituoidut 1-aryyli-indoliyhdisteet
DK0725061T3 (da) Substituerede indolderivater
IS4605A (is) Pýrrólidínýl metýl indól salt
GB9310092D0 (en) Indole derivatives
GB9302577D0 (en) Indole derivatives
DE59605373D1 (de) Substituierte Indol-Derivate
NO951241D0 (no) Forbedret indolbiosyntese
GB9309148D0 (en) Indole derivatives
GB9307080D0 (en) Indole derivatives
GB9319299D0 (en) Indole derivatives