FI961105A7 - Difluoristatoniviruksen vastaisia analogeja - Google Patents
Difluoristatoniviruksen vastaisia analogeja Download PDFInfo
- Publication number
- FI961105A7 FI961105A7 FI961105A FI961105A FI961105A7 FI 961105 A7 FI961105 A7 FI 961105A7 FI 961105 A FI961105 A FI 961105A FI 961105 A FI961105 A FI 961105A FI 961105 A7 FI961105 A7 FI 961105A7
- Authority
- FI
- Finland
- Prior art keywords
- difluorostatin
- antiviral
- analogues
- difluorostatin antiviral
- antiviral analogues
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
- C07D213/30—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/56—Amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Epoxy Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP93402194 | 1993-09-09 | ||
| PCT/US1994/009053 WO1995007257A1 (en) | 1993-09-09 | 1994-08-10 | Difluoro statone antiviral analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI961105A0 FI961105A0 (fi) | 1996-03-08 |
| FI961105L FI961105L (fi) | 1996-03-08 |
| FI961105A7 true FI961105A7 (fi) | 1996-03-08 |
Family
ID=8214747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI961105A FI961105A7 (fi) | 1993-09-09 | 1994-08-10 | Difluoristatoniviruksen vastaisia analogeja |
Country Status (20)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6028223A (en) * | 1995-08-30 | 2000-02-22 | G. D. Searle & Co. | Meta-guanidine, urea, thiourea or azacyclic amino benzoic acid compounds and derivatives thereof |
| KR100440643B1 (ko) * | 1999-01-28 | 2004-07-21 | 쥬가이 세이야쿠 가부시키가이샤 | 치환 페네틸아민 유도체 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH672792A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1985-02-19 | 1989-12-29 | Sandoz Ag | |
| US5066643A (en) * | 1985-02-19 | 1991-11-19 | Sandoz Ltd. | Fluorine and chlorine statine or statone containing peptides and method of use |
| WO1986006379A1 (en) * | 1985-04-19 | 1986-11-06 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
| GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
| NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
| FR2614533A1 (fr) * | 1987-04-23 | 1988-11-04 | Sandoz Sa | Nouveaux derives peptidiques, leur preparation et leur utilisation comme medicaments |
| GB2212158A (en) * | 1987-12-15 | 1989-07-19 | Sandoz Ltd | Trialkylsilymethyl-substituted peptides; renin inhibitors |
| IL90872A0 (en) * | 1988-07-08 | 1990-02-09 | Smithkline Beckman Corp | Retroviral protease binding peptides |
| HUT58764A (en) * | 1988-07-08 | 1992-03-30 | Smithkline Beckman Corp | Process for producing peptides, pharmaceutical compositions containing them and amino-acid intermediates |
| CA2010531A1 (en) * | 1989-03-06 | 1990-09-06 | Werner Neidhart | Amino acid derivatives |
| US5151438A (en) * | 1989-05-23 | 1992-09-29 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| EP0565631B1 (en) * | 1991-01-02 | 1996-09-18 | Merrell Pharmaceuticals Inc. | Anti-viral compounds |
| KR100220876B1 (ko) * | 1991-01-02 | 1999-10-01 | 슈테펜엘.네스비트 | 항 바이러스 화합물 |
| WO1993019059A1 (en) * | 1992-03-25 | 1993-09-30 | Pfizer Limited | Antiviral peptides |
| GB9210744D0 (en) * | 1992-05-20 | 1992-07-08 | Pfizer Ltd | Antiviral peptides |
| EP1148050A1 (en) * | 1992-05-21 | 2001-10-24 | Monsanto Company | Retroviral protease inhibitors |
| ATE196465T1 (de) * | 1993-07-08 | 2000-10-15 | Merrell Pharma Inc | Analoge von difluoro-staton |
| CN1152910A (zh) * | 1994-07-15 | 1997-06-25 | 默里尔药物公司 | 二氟斯塔酮抗病毒剂 |
-
1994
- 1994-08-10 WO PCT/US1994/009053 patent/WO1995007257A1/en active IP Right Grant
- 1994-08-10 FI FI961105A patent/FI961105A7/fi not_active IP Right Cessation
- 1994-08-10 HU HU9600601A patent/HUT74569A/hu unknown
- 1994-08-10 CN CN94193321A patent/CN1130898A/zh active Pending
- 1994-08-10 DE DE69418050T patent/DE69418050T2/de not_active Expired - Fee Related
- 1994-08-10 US US08/596,336 patent/US5831094A/en not_active Expired - Fee Related
- 1994-08-10 ES ES94925816T patent/ES2133573T3/es not_active Expired - Lifetime
- 1994-08-10 NZ NZ271825A patent/NZ271825A/en unknown
- 1994-08-10 EP EP94925816A patent/EP0717731B1/en not_active Expired - Lifetime
- 1994-08-10 AU AU75606/94A patent/AU683927B2/en not_active Ceased
- 1994-08-10 DK DK94925816T patent/DK0717731T3/da active
- 1994-08-10 AT AT94925816T patent/ATE179167T1/de not_active IP Right Cessation
- 1994-08-10 JP JP7508667A patent/JPH09502437A/ja not_active Ceased
- 1994-08-10 KR KR1019960701172A patent/KR100308839B1/ko not_active Expired - Fee Related
- 1994-08-10 CA CA002170607A patent/CA2170607C/en not_active Expired - Fee Related
- 1994-09-05 IL IL11086594A patent/IL110865A/xx not_active IP Right Cessation
- 1994-09-05 ZA ZA946815A patent/ZA946815B/xx unknown
- 1994-09-06 TW TW083108216A patent/TW282449B/zh active
-
1996
- 1996-03-01 NO NO960849A patent/NO960849L/no unknown
-
1998
- 1998-05-19 US US09/081,307 patent/US5948778A/en not_active Expired - Fee Related
-
1999
- 1999-05-27 GR GR990401441T patent/GR3030352T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ271825A (en) | 1997-11-24 |
| HUT74569A (en) | 1997-01-28 |
| CN1130898A (zh) | 1996-09-11 |
| KR960704838A (ko) | 1996-10-09 |
| NO960849D0 (no) | 1996-03-01 |
| IL110865A (en) | 1999-07-14 |
| HU9600601D0 (en) | 1996-05-28 |
| DE69418050T2 (de) | 1999-11-25 |
| DE69418050D1 (de) | 1999-05-27 |
| AU7560694A (en) | 1995-03-27 |
| ATE179167T1 (de) | 1999-05-15 |
| IL110865A0 (en) | 1994-11-28 |
| JPH09502437A (ja) | 1997-03-11 |
| TW282449B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1996-08-01 |
| US5948778A (en) | 1999-09-07 |
| WO1995007257A1 (en) | 1995-03-16 |
| EP0717731B1 (en) | 1999-04-21 |
| EP0717731A1 (en) | 1996-06-26 |
| ES2133573T3 (es) | 1999-09-16 |
| FI961105A0 (fi) | 1996-03-08 |
| AU683927B2 (en) | 1997-11-27 |
| CA2170607A1 (en) | 1995-03-16 |
| DK0717731T3 (da) | 1999-11-01 |
| CA2170607C (en) | 2000-02-22 |
| US5831094A (en) | 1998-11-03 |
| GR3030352T3 (en) | 1999-09-30 |
| ZA946815B (en) | 1995-04-24 |
| NO960849L (no) | 1996-03-01 |
| KR100308839B1 (ko) | 2002-10-04 |
| FI961105L (fi) | 1996-03-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |