FI960730A0 - Indolijohdannaiset 5alfa-reduktaasi-1-inhibiittoreina - Google Patents

Indolijohdannaiset 5alfa-reduktaasi-1-inhibiittoreina

Info

Publication number
FI960730A0
FI960730A0 FI960730A FI960730A FI960730A0 FI 960730 A0 FI960730 A0 FI 960730A0 FI 960730 A FI960730 A FI 960730A FI 960730 A FI960730 A FI 960730A FI 960730 A0 FI960730 A0 FI 960730A0
Authority
FI
Finland
Prior art keywords
pct
reductase
inhibitors
5alpha
indole derivatives
Prior art date
Application number
FI960730A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI960730A (fi
Inventor
Julian Blagg
Graham Nigel Maw
David James Rawson
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of FI960730A0 publication Critical patent/FI960730A0/fi
Publication of FI960730A publication Critical patent/FI960730A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/30Compounds having groups
    • C07C43/307Compounds having groups having acetal carbon atoms bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/30Compounds having groups
    • C07C43/313Compounds having groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/784Ketones containing a keto group bound to a six-membered aromatic ring polycyclic with all keto groups bound to a non-condensed ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/80Ketones containing a keto group bound to a six-membered aromatic ring containing halogen
    • C07C49/813Ketones containing a keto group bound to a six-membered aromatic ring containing halogen polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
FI960730A 1993-08-17 1996-02-16 Indolijohdannaiset 5alfa-reduktaasi-1-inhibiittoreina FI960730A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939317096A GB9317096D0 (en) 1993-08-17 1993-08-17 Indoles
PCT/EP1994/002563 WO1995005375A1 (en) 1993-08-17 1994-08-02 Indole derivatives as 5-alpha-reductase-1-inhibitors

Publications (2)

Publication Number Publication Date
FI960730A0 true FI960730A0 (fi) 1996-02-16
FI960730A FI960730A (fi) 1996-02-16

Family

ID=10740625

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960730A FI960730A (fi) 1993-08-17 1996-02-16 Indolijohdannaiset 5alfa-reduktaasi-1-inhibiittoreina

Country Status (18)

Country Link
US (1) US5912357A (es)
EP (1) EP0714390B1 (es)
JP (1) JP2833865B2 (es)
AT (1) ATE188695T1 (es)
AU (1) AU7497794A (es)
CA (1) CA2167397C (es)
CO (1) CO4290297A1 (es)
DE (1) DE69422629T2 (es)
DK (1) DK0714390T3 (es)
EC (1) ECSP941143A (es)
ES (1) ES2140552T3 (es)
FI (1) FI960730A (es)
GB (1) GB9317096D0 (es)
GR (1) GR3032845T3 (es)
IL (1) IL110627A0 (es)
PE (1) PE16695A1 (es)
PT (1) PT714390E (es)
WO (1) WO1995005375A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL109728A0 (en) * 1993-05-28 1994-08-26 Pfizer Res & Dev Indoles
GB9420529D0 (en) 1994-10-12 1994-11-30 Pfizer Ltd Indoles
GB9609641D0 (en) * 1996-05-09 1996-07-10 Pfizer Ltd Compounds useful in therapy
FR2796279B1 (fr) 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour le traitement de la seborrhee
FR2796274B1 (fr) * 1999-07-16 2001-09-21 Oreal Utilisation de l'acide 4,6-dimethoxy-indole 2-carboxylique ou de ses derives pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute
GB201102913D0 (en) 2011-02-18 2011-04-06 Univ Birmingham Novel therapeutic

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9011335D0 (en) * 1990-05-21 1990-07-11 Fujisawa Pharmaceutical Co Indolebutyric acid derivatives and process for preparation thereof
GB9115951D0 (en) * 1991-07-24 1991-09-11 Pfizer Ltd Indoles
GB9204365D0 (en) * 1992-02-28 1992-04-08 Pfizer Ltd Indoles
IL109728A0 (en) * 1993-05-28 1994-08-26 Pfizer Res & Dev Indoles

Also Published As

Publication number Publication date
CO4290297A1 (es) 1996-04-17
ES2140552T3 (es) 2000-03-01
DE69422629D1 (en) 2000-02-17
US5912357A (en) 1999-06-15
CA2167397A1 (en) 1995-02-23
EP0714390A1 (en) 1996-06-05
WO1995005375A1 (en) 1995-02-23
JP2833865B2 (ja) 1998-12-09
AU7497794A (en) 1995-03-14
EP0714390B1 (en) 2000-01-12
FI960730A (fi) 1996-02-16
ECSP941143A (es) 1995-01-16
PT714390E (pt) 2000-06-30
DK0714390T3 (da) 2000-05-01
DE69422629T2 (de) 2000-06-29
IL110627A0 (en) 1994-11-11
GB9317096D0 (en) 1993-09-29
GR3032845T3 (en) 2000-07-31
ATE188695T1 (de) 2000-01-15
JPH09500142A (ja) 1997-01-07
PE16695A1 (es) 1995-06-21
CA2167397C (en) 2000-12-12

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