FI954065A - Dihydro-2,3-bentsodiatsepiinijohdannaisen fyysinen olomuoto - Google Patents

Dihydro-2,3-bentsodiatsepiinijohdannaisen fyysinen olomuoto Download PDF

Info

Publication number
FI954065A
FI954065A FI954065A FI954065A FI954065A FI 954065 A FI954065 A FI 954065A FI 954065 A FI954065 A FI 954065A FI 954065 A FI954065 A FI 954065A FI 954065 A FI954065 A FI 954065A
Authority
FI
Finland
Prior art keywords
dihydro
physical state
benzodiazepine derivative
acetyl
methyl
Prior art date
Application number
FI954065A
Other languages
English (en)
Swedish (sv)
Other versions
FI954065A0 (fi
FI112490B (fi
Inventor
Benjamin Alan Anderson
Marvin Martin Hansen
Jeffrey Thomas Vincenzi
David Lee Varie
Jr Milton Joseph Zmijewski
Allen Robert Harkness
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/413,024 external-priority patent/US6288057B1/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI954065A0 publication Critical patent/FI954065A0/fi
Publication of FI954065A publication Critical patent/FI954065A/fi
Application granted granted Critical
Publication of FI112490B publication Critical patent/FI112490B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
FI954065A 1994-08-31 1995-08-30 (R)-7-asetyyli-5-(4-aminofenyyli)-8,9-dihydro-8-metyyli-7H-1,3-dioksolo[4,5-h][2,3]bentsodiatsepiinin fysikaalinen olomuoto FI112490B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29864594A 1994-08-31 1994-08-31
US29864594 1994-08-31
US08/413,024 US6288057B1 (en) 1994-08-31 1995-03-28 Physical form of dihydro-2,3-benzodiazepine derivative
US41302495 1995-03-28

Publications (3)

Publication Number Publication Date
FI954065A0 FI954065A0 (fi) 1995-08-30
FI954065A true FI954065A (fi) 1996-03-01
FI112490B FI112490B (fi) 2003-12-15

Family

ID=26970797

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954065A FI112490B (fi) 1994-08-31 1995-08-30 (R)-7-asetyyli-5-(4-aminofenyyli)-8,9-dihydro-8-metyyli-7H-1,3-dioksolo[4,5-h][2,3]bentsodiatsepiinin fysikaalinen olomuoto

Country Status (20)

Country Link
EP (1) EP0699676B1 (fi)
JP (1) JP3449834B2 (fi)
CN (1) CN1073995C (fi)
AT (1) ATE199086T1 (fi)
AU (1) AU696243B2 (fi)
BR (1) BR9503844A (fi)
CA (1) CA2157247C (fi)
CZ (1) CZ288267B6 (fi)
DE (1) DE69520059T2 (fi)
DK (1) DK0699676T3 (fi)
ES (1) ES2153879T3 (fi)
FI (1) FI112490B (fi)
GR (1) GR3035801T3 (fi)
HK (1) HK1013819A1 (fi)
HU (1) HUT72673A (fi)
IL (1) IL115101A (fi)
NO (1) NO310462B1 (fi)
NZ (1) NZ272897A (fi)
PT (1) PT699676E (fi)
TR (1) TR199501072A2 (fi)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2338492A1 (en) 2009-12-24 2011-06-29 Universidad del Pais Vasco Methods and compositions for the treatment of alzheimer
NO2780523T3 (fi) * 2014-06-25 2018-03-24

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU219778B (hu) 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
HU219777B (hu) * 1993-07-02 2001-07-30 Gyógyszerkutató Intézet Kft. Optikailag aktív 1-(4-nitro-fenil)-4-metil-7,8-metiléndioxi-3,4-dihidro-5H-2,3-benzodiazepin és eljárás előállítására

Also Published As

Publication number Publication date
FI954065A0 (fi) 1995-08-30
AU696243B2 (en) 1998-09-03
DK0699676T3 (da) 2001-02-26
HU9502547D0 (en) 1995-10-30
HUT72673A (en) 1996-05-28
EP0699676A1 (en) 1996-03-06
NZ272897A (en) 1997-03-24
NO310462B1 (no) 2001-07-09
GR3035801T3 (en) 2001-07-31
CN1122338A (zh) 1996-05-15
FI112490B (fi) 2003-12-15
IL115101A (en) 1998-12-27
CA2157247C (en) 2000-10-24
NO953395D0 (no) 1995-08-30
JP3449834B2 (ja) 2003-09-22
AU3035695A (en) 1996-03-14
TR199501072A2 (tr) 1996-06-21
EP0699676B1 (en) 2001-02-07
ATE199086T1 (de) 2001-02-15
DE69520059D1 (de) 2001-03-15
CN1073995C (zh) 2001-10-31
DE69520059T2 (de) 2001-06-21
HK1013819A1 (en) 1999-09-10
CZ288267B6 (en) 2001-05-16
IL115101A0 (en) 1995-12-08
ES2153879T3 (es) 2001-03-16
PT699676E (pt) 2001-05-31
NO953395L (no) 1996-03-01
CZ222095A3 (en) 1996-03-13
JPH0892255A (ja) 1996-04-09
BR9503844A (pt) 1996-09-10

Similar Documents

Publication Publication Date Title
ATE119774T1 (de) Imidazopyridinderivate und ihre verwendung.
ATE302180T1 (de) Zwischenprodukte zur herstellung von non-peptiden retroviralproteasehemmenden verbindungen
IL120266A (en) Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
NO904377L (no) Tricykliske karbapenemforbindelser.
ATE81653T1 (de) Dideoxydidehydrocarbocyclische nukleoside.
FI954066A (fi) Dihydro-2,3-bentsodiatsepiinijohdannaisten kiteinen muoto
FI954065A (fi) Dihydro-2,3-bentsodiatsepiinijohdannaisen fyysinen olomuoto
MY118394A (en) Crystalline form of dihydro-2, 3-benzodiazepine derivative
ES2094885T3 (es) Unas composiciones de materia en la forma de 1-alquil-2-acil-1,2-disulfonil hidracinas y su uso.
FI904449A0 (fi) N-azasicyklo/3.3.0/oktanamider av aromatiska syror.
DE69221006D1 (de) Mitomycinderivate
DE60103732D1 (de) Pyrimidinderivate mit antitumor-wirkung
ATE100449T1 (de) 1,3-dioxolan-benzoesaeure und derivate davon.
MY116368A (en) Physical form of dihydro-2, 3-benzodiazepine derivative