FI945227A - Sykliset heksapeptidit, niiden valmistus ja käyttö - Google Patents

Sykliset heksapeptidit, niiden valmistus ja käyttö Download PDF

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Publication number
FI945227A
FI945227A FI945227A FI945227A FI945227A FI 945227 A FI945227 A FI 945227A FI 945227 A FI945227 A FI 945227A FI 945227 A FI945227 A FI 945227A FI 945227 A FI945227 A FI 945227A
Authority
FI
Finland
Prior art keywords
alkyl
cycloalkyl
alkoxy
alpha
amino acid
Prior art date
Application number
FI945227A
Other languages
English (en)
Swedish (sv)
Other versions
FI945227A0 (fi
Inventor
Mitsuhiro Wakimasu
Takashi Kikuchi
Akira Kawada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI945227A0 publication Critical patent/FI945227A0/fi
Publication of FI945227A publication Critical patent/FI945227A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57536—Endothelin, vasoactive intestinal contractor [VIC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI945227A 1993-11-08 1994-11-07 Sykliset heksapeptidit, niiden valmistus ja käyttö FI945227A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP27872293 1993-11-08
JP11236594 1994-05-26

Publications (2)

Publication Number Publication Date
FI945227A0 FI945227A0 (fi) 1994-11-07
FI945227A true FI945227A (fi) 1995-05-09

Family

ID=26451544

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945227A FI945227A (fi) 1993-11-08 1994-11-07 Sykliset heksapeptidit, niiden valmistus ja käyttö

Country Status (7)

Country Link
US (1) US5948754A (fi)
EP (1) EP0655463B1 (fi)
AT (1) ATE184021T1 (fi)
CA (1) CA2135151A1 (fi)
DE (1) DE69420361T2 (fi)
FI (1) FI945227A (fi)
NO (1) NO944241L (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0714909A1 (en) * 1994-12-01 1996-06-05 Takeda Chemical Industries, Ltd. Composition for prophylaxis or treatment of pulmonary circulatory diseases
US6251861B1 (en) 1996-06-27 2001-06-26 Takeda Chemical Industries, Ltd. Treatment of cerebral infarction using cyclic hexapeptides
CA2789114C (en) 2001-11-01 2014-03-25 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
US8394757B2 (en) 2002-10-24 2013-03-12 Spectrum Pharmaceuticals, Inc. Sensitization of tumor cells to radiation therapy through the administration of endothelin agonists
US8026216B2 (en) 2002-10-24 2011-09-27 Spectrum Pharmaceuticals, Inc. Methods and compositions for contributing to the treatment of cancers
US20070032422A1 (en) 2002-10-24 2007-02-08 Spectrum Pharmaceuticals, Inc. Methods, compositions and articles of manufacture for contributing to the treatment of cancers
CN1729012B (zh) * 2002-10-24 2013-05-22 伊利诺伊大学评议会 治疗实体瘤的组合物
US8217010B2 (en) 2002-10-24 2012-07-10 The Board Of Trustees Of The University Of Illinois Methods, compositions and articles of manufacture for contributing to the treatment of solid tumors
US9308235B2 (en) 2012-05-09 2016-04-12 Spectrum Pharmaceuticals, Inc. Treatment of primary and metastatic carcinoma

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032559C (en) * 1989-12-28 2001-11-06 Kiyofumi Ishikawa Endothelin antagonistic cyclic pentapeptides
DK0528312T3 (da) * 1991-08-13 1997-12-29 Takeda Chemical Industries Ltd Cykliske peptider og anvendelse deraf
EP0552417B1 (en) * 1991-11-19 1999-07-07 Takeda Chemical Industries, Ltd. Cyclic peptides and use thereof
TW217417B (fi) * 1991-12-04 1993-12-11 Manyu Seiyaku Kk

Also Published As

Publication number Publication date
US5948754A (en) 1999-09-07
FI945227A0 (fi) 1994-11-07
ATE184021T1 (de) 1999-09-15
EP0655463A1 (en) 1995-05-31
NO944241D0 (no) 1994-11-07
EP0655463B1 (en) 1999-09-01
CA2135151A1 (en) 1995-05-09
NO944241L (no) 1995-05-09
DE69420361D1 (de) 1999-10-07
DE69420361T2 (de) 1999-12-16

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