FI944848A0 - Fenyylisubstituoidut sykloalkyylihydroksiureajohdannaiset, jotka inhiboivat lipoksygenaasia - Google Patents

Fenyylisubstituoidut sykloalkyylihydroksiureajohdannaiset, jotka inhiboivat lipoksygenaasia

Info

Publication number
FI944848A0
FI944848A0 FI944848A FI944848A FI944848A0 FI 944848 A0 FI944848 A0 FI 944848A0 FI 944848 A FI944848 A FI 944848A FI 944848 A FI944848 A FI 944848A FI 944848 A0 FI944848 A0 FI 944848A0
Authority
FI
Finland
Prior art keywords
alkyl
halosubstituted
phenylthio
phenoxy
phenyl
Prior art date
Application number
FI944848A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI944848A (fi
Inventor
Akiyoshi Kawai
Kazunari Nakao
Rodney W Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI944848A0 publication Critical patent/FI944848A0/fi
Publication of FI944848A publication Critical patent/FI944848A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/46—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms
    • C07C323/47—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having at least one of the nitrogen atoms, not being part of nitro or nitroso groups, further bound to other hetero atoms to oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
FI944848A 1992-04-17 1994-10-14 Fenyylisubstituoidut sykloalkyylihydroksiureajohdannaiset, jotka inhiboivat lipoksygenaasia FI944848A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4098150A JPH05294921A (ja) 1992-04-17 1992-04-17 新規なフェニル置換シクロアルキル尿素誘導体および組成物
PCT/US1993/001341 WO1993021149A1 (en) 1992-04-17 1993-02-18 Phenyl substituted cycloalkyl hydroxyurea derivatives which inhibit lipoxygenase

Publications (2)

Publication Number Publication Date
FI944848A0 true FI944848A0 (fi) 1994-10-14
FI944848A FI944848A (fi) 1994-10-14

Family

ID=14212150

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944848A FI944848A (fi) 1992-04-17 1994-10-14 Fenyylisubstituoidut sykloalkyylihydroksiureajohdannaiset, jotka inhiboivat lipoksygenaasia

Country Status (10)

Country Link
EP (1) EP0636119B1 (de)
JP (1) JPH05294921A (de)
AT (1) ATE159933T1 (de)
CA (1) CA2133218C (de)
DE (1) DE69315069T2 (de)
DK (1) DK0636119T3 (de)
ES (1) ES2108266T3 (de)
FI (1) FI944848A (de)
GR (1) GR3025692T3 (de)
WO (1) WO1993021149A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW448144B (en) * 1993-08-19 2001-08-01 Pfizer Phenoxyphenyl cyclopentenyl hydroxyureas
AU1120795A (en) * 1993-12-22 1995-07-10 Pfizer Inc. Phenylthiophenyl cycloalkenyl hydroxyureas as lipoxygenase inhibitors
US6832204B1 (en) * 1999-12-27 2004-12-14 Ge-Harris Railway Electronics, Llc Train building planning method
CA2570800A1 (en) 2004-06-18 2006-01-26 Wyeth Processes for preparing 6-alkyl-5-arylsulfonyl- dihydrophenanthridines
EP1888523B1 (de) * 2005-06-03 2011-10-26 Abbott Laboratories Cyclobutylaminderivate

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120752A (en) * 1989-12-28 1992-06-09 Abbott Laboratories Cyclopropyl derivative lipoxygenase inhibitors
DK0540673T3 (da) * 1990-07-25 1997-03-24 Abbott Lab Acetylen-derivater med lipoxygenaseinhiberende virkning
GB9025514D0 (en) * 1990-11-23 1991-01-09 Wellcome Found Anti-inflammatory compounds
JP3007138B2 (ja) * 1990-11-27 2000-02-07 ファイザー製薬株式会社 新規なヒドロキサム酸とｎ―ヒドロキシ尿素誘導体およびそれらの組成物
US5283361A (en) * 1991-04-23 1994-02-01 Eli Lilly And Company N-hydroxy-N-[3-[2-(halophenylthio)phenyl]prop-2-enyl]ureas as lipoxygenase inhibitors
JP2989951B2 (ja) * 1991-10-25 1999-12-13 ファイザー製薬株式会社 新規なシクロアルキル尿素誘導体および組成物
US5187192A (en) * 1992-03-13 1993-02-16 Abbott Laboratories Cyclobutyl derivatives having lipoxygenase inhibitory activity

Also Published As

Publication number Publication date
JPH05294921A (ja) 1993-11-09
CA2133218A1 (en) 1993-10-28
ATE159933T1 (de) 1997-11-15
WO1993021149A1 (en) 1993-10-28
GR3025692T3 (en) 1998-03-31
FI944848A (fi) 1994-10-14
EP0636119B1 (de) 1997-11-05
CA2133218C (en) 2002-07-09
DE69315069T2 (de) 1998-02-26
DE69315069D1 (en) 1997-12-11
EP0636119A1 (de) 1995-02-01
ES2108266T3 (es) 1997-12-16
DK0636119T3 (da) 1997-12-22

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