FI941300A - Bentseenijohdannaiset - Google Patents

Bentseenijohdannaiset Download PDF

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Publication number
FI941300A
FI941300A FI941300A FI941300A FI941300A FI 941300 A FI941300 A FI 941300A FI 941300 A FI941300 A FI 941300A FI 941300 A FI941300 A FI 941300A FI 941300 A FI941300 A FI 941300A
Authority
FI
Finland
Prior art keywords
hydrogen
hydroxy
general formula
lower alkyl
benzene derivatives
Prior art date
Application number
FI941300A
Other languages
English (en)
Swedish (sv)
Other versions
FI941300A0 (fi
Inventor
Kenji Hayashi
Nobuhisa Watanabe
Koichi Nose
Hiroshi Tanaka
Issei Ohtsuka
Motoji Kogushi
Hironobu Hiyoshi
Hiroko Kobayashi
Toshie Yamada
Toru Horie
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FI941300A publication Critical patent/FI941300A/fi
Publication of FI941300A0 publication Critical patent/FI941300A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
    • C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI941300A 1992-07-20 1994-03-18 Bentseenijohdannaiset FI941300A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP21324292 1992-07-20
JP28343292 1992-09-30
PCT/JP1993/000961 WO1994002452A1 (en) 1992-07-20 1993-07-12 Benzene derivative

Publications (2)

Publication Number Publication Date
FI941300A true FI941300A (fi) 1994-03-18
FI941300A0 FI941300A0 (fi) 1994-03-18

Family

ID=26519683

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941300A FI941300A0 (fi) 1992-07-20 1994-03-18 Bentseenijohdannaiset

Country Status (10)

Country Link
US (1) US5462958A (fi)
EP (1) EP0609457B1 (fi)
JP (1) JP3612328B2 (fi)
CN (1) CN1084164A (fi)
AT (1) ATE159715T1 (fi)
CA (1) CA2115915A1 (fi)
DE (1) DE69314929T2 (fi)
FI (1) FI941300A0 (fi)
HU (1) HUT67475A (fi)
WO (1) WO1994002452A1 (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0773218A1 (en) * 1995-11-13 1997-05-14 Mitsubishi Chemical Corporation N-(Piperazinylalkoxyphenyl)-N'phenylalkylurea derivatives as ACAT inhibitors for the treatment of atheroschlerosis

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792187A (fr) * 1971-12-03 1973-03-30 Sumitomo Chemical Co Nouveaux derives d'alkylamines
GB2056968A (en) * 1979-08-21 1981-03-25 Fujisawa Pharmaceutical Co Piperazine derivative, processes for the preparation thereof and pharmaceutical composition comprising the same
GB2062622A (en) * 1979-11-07 1981-05-28 American Cyanamid Co Aniline Derivatives
IT1168008B (it) * 1981-07-31 1987-05-20 Zambon Spa Imidazol-eteri ed ester, procedimenti per prepararli e composizioni farmaceutiche che li contengono
IL67417A (en) * 1982-01-26 1989-10-31 American Cyanamid Co Antiatherosclerotic substituted ureas,process for their preparation and pharmaceutical compositions containing them
US4623662A (en) * 1985-05-23 1986-11-18 American Cyanamid Company Antiatherosclerotic ureas and thioureas
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
US4716175A (en) * 1987-02-24 1987-12-29 Warner-Lambert Company Saturated fatty acid amides as inhibitors of acyl-CoA:cholesterol acyltransferase
US4824843A (en) * 1987-06-25 1989-04-25 Warner-Lambert Company Substituted amide inhibitors of cholesterol absorption
EP0344425B1 (en) * 1988-03-30 1993-12-08 Warner-Lambert Company N-[[(2,6-disubstituted)phenyl]-N'- arylalkyl] ureas as antihypercholesterolemic and antiatherosclerotic agents
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
US5668136A (en) * 1990-09-25 1997-09-16 Eisai Co., Ltd. Trisubstituted benzene derivatives, composition and methods of treatment
WO1992009572A1 (fr) * 1990-11-26 1992-06-11 Taisho Pharmaceutical Co., Ltd. Derive d'anilide
JPH05320143A (ja) * 1992-03-18 1993-12-03 Mochida Pharmaceut Co Ltd 新規ピリミジン誘導体

Also Published As

Publication number Publication date
EP0609457B1 (en) 1997-10-29
DE69314929T2 (de) 1998-03-19
JP3612328B2 (ja) 2005-01-19
US5462958A (en) 1995-10-31
HU9400795D0 (en) 1994-06-28
ATE159715T1 (de) 1997-11-15
HUT67475A (en) 1995-04-28
EP0609457A4 (en) 1994-08-24
DE69314929D1 (de) 1997-12-04
CA2115915A1 (en) 1994-02-03
FI941300A0 (fi) 1994-03-18
EP0609457A1 (en) 1994-08-10
WO1994002452A1 (en) 1994-02-03
CN1084164A (zh) 1994-03-23

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Legal Events

Date Code Title Description
FD Application lapsed