FI931625A0 - Kromaner och tiokromaner med retinoidlik aktivitet - Google Patents

Kromaner och tiokromaner med retinoidlik aktivitet

Info

Publication number
FI931625A0
FI931625A0 FI931625A FI931625A FI931625A0 FI 931625 A0 FI931625 A0 FI 931625A0 FI 931625 A FI931625 A FI 931625A FI 931625 A FI931625 A FI 931625A FI 931625 A0 FI931625 A0 FI 931625A0
Authority
FI
Finland
Prior art keywords
tiokromaner
retinoidlik
kromaner
aktivitet
och
Prior art date
Application number
FI931625A
Other languages
English (en)
Other versions
FI931625A (fi
Inventor
Roshantha A S Chandraratna
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of FI931625A0 publication Critical patent/FI931625A0/fi
Publication of FI931625A publication Critical patent/FI931625A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/14—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 6 and unsubstituted in position 7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI931625A 1990-10-09 1993-04-08 Kromaner och tiokromaner med retinoidlik aktivitet FI931625A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59488290A 1990-10-09 1990-10-09
PCT/US1991/006901 WO1992006084A1 (en) 1990-10-09 1991-09-24 Chromans and thiochromans with retinoid-like activity

Publications (2)

Publication Number Publication Date
FI931625A0 true FI931625A0 (fi) 1993-04-08
FI931625A FI931625A (fi) 1993-06-07

Family

ID=24380813

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931625A FI931625A (fi) 1990-10-09 1993-04-08 Kromaner och tiokromaner med retinoidlik aktivitet

Country Status (12)

Country Link
EP (1) EP0553156A4 (fi)
JP (1) JPH06501948A (fi)
AU (1) AU652189B2 (fi)
CA (1) CA2092178A1 (fi)
FI (1) FI931625A (fi)
HU (1) HUT63405A (fi)
IE (1) IE913569A1 (fi)
IL (1) IL99617A0 (fi)
PL (1) PL168679B1 (fi)
PT (1) PT99188A (fi)
WO (1) WO1992006084A1 (fi)
ZA (1) ZA918026B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2094350T3 (es) * 1991-02-13 1997-01-16 Allergan Inc Cromano y tiocromanos con sustituyentes de feniletinilo en la posicion 7 que tienen actividad biologica de tipo retinoide.
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5451603A (en) * 1993-03-11 1995-09-19 Zymogenetics, Inc. 3,4-diarylchromans for treatment of dermatitis
US6121309A (en) * 1996-03-18 2000-09-19 Eisai Co., Ltd. Fused-ring carboxylic acid derivatives
US6740676B2 (en) * 2002-03-19 2004-05-25 Allergan, Inc. 4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-benzoic and 2-[4-[(8-ethynyl, 8-vinyl or 8-ethynyl-methyl)-6-chromanoyl]-phenyl]-acetic acid, their esters and salts having cytochrome p450rai inhibitory activity
EP2453746A4 (en) 2009-07-16 2013-04-24 Stiefel Laboratories TAZAROTENDERIVATE
CN107176945B (zh) * 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810804A (en) * 1987-03-26 1989-03-07 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity
US4980369A (en) * 1989-09-19 1990-12-25 Allergan, Inc. Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity
ES2094350T3 (es) * 1991-02-13 1997-01-16 Allergan Inc Cromano y tiocromanos con sustituyentes de feniletinilo en la posicion 7 que tienen actividad biologica de tipo retinoide.

Also Published As

Publication number Publication date
HU9301030D0 (en) 1993-07-28
JPH06501948A (ja) 1994-03-03
IL99617A0 (en) 1992-08-18
HUT63405A (en) 1993-08-30
WO1992006084A1 (en) 1992-04-16
PL168679B1 (en) 1996-03-29
AU8721091A (en) 1992-04-28
PT99188A (pt) 1992-09-30
IE913569A1 (en) 1992-04-22
ZA918026B (en) 1992-06-24
FI931625A (fi) 1993-06-07
EP0553156A1 (en) 1993-08-04
CA2092178A1 (en) 1992-04-10
EP0553156A4 (en) 1993-11-18
AU652189B2 (en) 1994-08-18

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Legal Events

Date Code Title Description
FD Application lapsed