FI930277A - Omaettade 17b-substituerade 3-karboxisteroider - Google Patents

Omaettade 17b-substituerade 3-karboxisteroider Download PDF

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Publication number
FI930277A
FI930277A FI930277A FI930277A FI930277A FI 930277 A FI930277 A FI 930277A FI 930277 A FI930277 A FI 930277A FI 930277 A FI930277 A FI 930277A FI 930277 A FI930277 A FI 930277A
Authority
FI
Finland
Prior art keywords
group
chem
hydrogen
alkyl group
cycloalkyl
Prior art date
Application number
FI930277A
Other languages
English (en)
Other versions
FI930277A0 (fi
Inventor
Achille Panzeri
Marcella Nesi
Salle Enrico Di
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI930277A0 publication Critical patent/FI930277A0/fi
Publication of FI930277A publication Critical patent/FI930277A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Details Of Garments (AREA)
  • Ceramic Products (AREA)
  • Dental Preparations (AREA)
  • Medicines Containing Plant Substances (AREA)
FI930277A 1991-05-24 1993-01-22 Omaettade 17b-substituerade 3-karboxisteroider FI930277A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI911432A IT1259419B (it) 1991-05-24 1991-05-24 Steroidi 3-carbossi 17b - sostituiti insaturi utili come inibitori della testosterone 5 a reduttasi
PCT/EP1992/001153 WO1992020700A1 (en) 1991-05-24 1992-05-22 UNSATURATED 17β-SUBSTITUTED 3-CARBOXY STEROIDS

Publications (2)

Publication Number Publication Date
FI930277A0 FI930277A0 (fi) 1993-01-22
FI930277A true FI930277A (fi) 1993-01-22

Family

ID=11359980

Family Applications (1)

Application Number Title Priority Date Filing Date
FI930277A FI930277A (fi) 1991-05-24 1993-01-22 Omaettade 17b-substituerade 3-karboxisteroider

Country Status (26)

Country Link
US (1) US5212166A (fi)
EP (2) EP0540717B1 (fi)
JP (1) JP3226919B2 (fi)
CN (1) CN1035055C (fi)
AT (1) ATE155792T1 (fi)
AU (1) AU655280B2 (fi)
CA (1) CA2087953A1 (fi)
CZ (1) CZ281309B6 (fi)
DE (1) DE69221074T2 (fi)
DK (1) DK0540717T3 (fi)
ES (1) ES2106185T3 (fi)
FI (1) FI930277A (fi)
HU (1) HUT64083A (fi)
ID (1) ID954B (fi)
IE (1) IE921634A1 (fi)
IL (1) IL101947A (fi)
IT (1) IT1259419B (fi)
MX (1) MX9202438A (fi)
MY (1) MY131089A (fi)
NO (1) NO930244L (fi)
NZ (1) NZ242850A (fi)
RU (1) RU2104283C1 (fi)
TW (1) TW213467B (fi)
WO (1) WO1992020700A1 (fi)
YU (1) YU52992A (fi)
ZA (1) ZA923758B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR950701340A (ko) * 1992-04-30 1995-03-23 스튜어트 알. 슈터 17알파 및 17베타-치환된 에스트라-1,3,5,(10)-트리엔-3-카르복실산(17α AND 17β-SUBSTITUTED ESTRA-1,2,3(10)-TRIENE-3-CARBOXYLIC ACID)
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
CN1133005A (zh) * 1993-09-03 1996-10-09 史密丝克莱恩比彻姆公司 稳定的片剂
GB9324371D0 (en) * 1993-11-26 1994-01-12 Erba Carlo Spa Side chain fluoro substituted 3-carboxysteroids
US5430157A (en) * 1993-12-13 1995-07-04 Eli Lilly And Company Reduced phenanthrenes
GB9402041D0 (en) * 1994-02-03 1994-03-30 Smithkline Beecham Corp Compounds
US5714480A (en) * 1994-03-31 1998-02-03 Smithkline Beecham Corporation Treating cardiovascular disease with steroidal 5-alpha-reductase inhibitors
WO1995028413A1 (en) * 1994-04-15 1995-10-26 Smithkline Beecham Corporation 17β-SUBSTITUTED 3-CARBOXY STEROIDS THAT INHIBIT 5-α-REDUCTASE
GB9415183D0 (en) * 1994-07-28 1994-09-21 Erba Carlo Spa 3-carboxysteroids with a fluorinated side-chain
US5543417A (en) * 1994-10-21 1996-08-06 Merck & Co., Inc. Combination method of treating acne using 4-AZA-5α-cholestan-ones and 4-AZA-5α-androstan-ones as selective 5α-reductase inhibitors with anti-bacterial, keratolytic, or anti-inflammatory agents
WO1999061055A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
WO2007035716A2 (en) 2005-09-16 2007-03-29 Raptor Pharmaceutical Inc. Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4910226A (en) * 1987-04-29 1990-03-20 Smithkline Beckman Corporation Steroid 5-alpha-reductase inhibitors
US5041433A (en) * 1987-04-29 1991-08-20 Smithkline Beecham Corporation 11-keto or hydroxy 3,5-diene steroids as inhibitors of steriod 5-α-reductase
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase
US5091380A (en) * 1990-06-28 1992-02-25 Merck & Co., Inc. N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors
ATE154937T1 (de) * 1992-04-20 1997-07-15 Sankyo Co Steroide zur behandlung von prostatisch- hypertrophe, ihre herstellung und verwendung

Also Published As

Publication number Publication date
MY131089A (en) 2007-07-31
NZ242850A (en) 1994-01-26
YU52992A (sh) 1995-03-27
IL101947A (en) 1996-01-19
DE69221074T2 (de) 1997-11-13
MX9202438A (es) 1992-11-01
IE921634A1 (en) 1992-12-02
HU9300176D0 (en) 1993-04-28
ZA923758B (en) 1993-01-27
EP0540717A1 (en) 1993-05-12
NO930244D0 (no) 1993-01-25
HUT64083A (en) 1993-11-29
CN1035055C (zh) 1997-06-04
DK0540717T3 (da) 1997-08-18
AU655280B2 (en) 1994-12-15
CZ281309B6 (cs) 1996-08-14
ES2106185T3 (es) 1997-11-01
DE69221074D1 (de) 1997-09-04
JP3226919B2 (ja) 2001-11-12
FI930277A0 (fi) 1993-01-22
JPH06500342A (ja) 1994-01-13
ID954B (id) 1996-09-25
ITMI911432A0 (it) 1991-05-24
TW213467B (fi) 1993-09-21
CZ26593A3 (en) 1993-11-17
EP0517047A1 (en) 1992-12-09
IT1259419B (it) 1996-03-18
US5212166A (en) 1993-05-18
WO1992020700A1 (en) 1992-11-26
EP0540717B1 (en) 1997-07-23
ATE155792T1 (de) 1997-08-15
CN1067057A (zh) 1992-12-16
AU1778192A (en) 1992-12-30
NO930244L (no) 1993-01-27
CA2087953A1 (en) 1992-11-25
RU2104283C1 (ru) 1998-02-10
ITMI911432A1 (it) 1992-11-24

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Legal Events

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