FI922143A0 - Muscarinreceptorantagonister. - Google Patents
Muscarinreceptorantagonister.Info
- Publication number
- FI922143A0 FI922143A0 FI922143A FI922143A FI922143A0 FI 922143 A0 FI922143 A0 FI 922143A0 FI 922143 A FI922143 A FI 922143A FI 922143 A FI922143 A FI 922143A FI 922143 A0 FI922143 A0 FI 922143A0
- Authority
- FI
- Finland
- Prior art keywords
- muscarinreceptorantagonister
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909020051A GB9020051D0 (en) | 1990-09-13 | 1990-09-13 | Muscarinic receptor antagonists |
PCT/EP1991/001705 WO1992005172A2 (en) | 1990-09-13 | 1991-09-09 | Muscarinic receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
FI922143A FI922143A (fi) | 1992-05-12 |
FI922143A0 true FI922143A0 (fi) | 1992-05-12 |
Family
ID=10682161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI922143A FI922143A0 (fi) | 1990-09-13 | 1992-05-12 | Muscarinreceptorantagonister. |
Country Status (9)
Country | Link |
---|---|
US (1) | US5397800A (ja) |
EP (1) | EP0510129A1 (ja) |
JP (1) | JPH07119213B2 (ja) |
CA (1) | CA2068527A1 (ja) |
FI (1) | FI922143A0 (ja) |
GB (1) | GB9020051D0 (ja) |
IE (1) | IE913210A1 (ja) |
PT (1) | PT98929B (ja) |
WO (1) | WO1992005172A2 (ja) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9822945D0 (en) * | 1998-10-20 | 1998-12-16 | Isis Innovations Ltd | Epibatidine analogues |
US6946475B1 (en) | 1999-04-07 | 2005-09-20 | University Of Virginia Patent Foundation | Anticancer calcium channel blockers |
EP1165508B1 (en) * | 1999-04-07 | 2004-06-23 | The University of Virginia Patent Foundation | Anticancer calcium channel blockers |
DE10044905A1 (de) * | 2000-09-12 | 2002-03-21 | Merck Patent Gmbh | (2-Azabicyclo[2.2.1]hept-7-yl)methanol-Derivate als nikontinische Acetylcholinrezeptor Agonisten |
DE10118551A1 (de) * | 2001-04-14 | 2002-10-17 | Merck Patent Gmbh | Nikotinische Acetylcholinrezeptor Liganden |
AU2002345266B2 (en) | 2002-07-08 | 2009-07-02 | Ranbaxy Laboratories Limited | 3,6-disubstituted azabicyclo [3.1.0]hexane derivatives useful as muscarinic receptor antagonists |
US6875774B2 (en) | 2002-08-06 | 2005-04-05 | The University Of North Carolina | Aza-bridged bicyclic amine derivatives for use as novel cholinergic receptor ligands |
EP1534675B1 (en) * | 2002-08-23 | 2009-02-25 | Ranbaxy Laboratories, Ltd. | Fluoro and sulphonylamino containing 3,6-disubstituted azabicyclo¬3.1.0 hexane derivatives as muscarinic receptor antagonists |
EP2177511A2 (en) * | 2002-12-10 | 2010-04-21 | Ranbaxy Laboratories Limited | Process for preparing 3,6-disubstituted azabicyclo derivatives |
US7488748B2 (en) * | 2003-01-28 | 2009-02-10 | Ranbaxy Laboratories Limited | 3,6-Disubstituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
US7517905B2 (en) * | 2003-04-09 | 2009-04-14 | Ranbaxy Laboratories Limited | Substituted azabicyclo hexane derivatives as muscarinic receptor antagonists |
BRPI0409302A (pt) * | 2003-04-11 | 2006-04-11 | Ranbaxy Lab Ltd | derivados azabiciclo como antagonistas de recetores muscarìnicos, método para sua preparação e composição farmacêutica contendo os mesmos |
WO2006005980A1 (en) * | 2004-06-16 | 2006-01-19 | Ranbaxy Laboratories Limited | Xanthine derivatives useful as muscarinic receptor antagonists |
WO2006018708A2 (en) * | 2004-08-19 | 2006-02-23 | Ranbaxy Laboratories Limited | Pyrrolidine derivatives as muscarinic receptor antagonists |
US20080280883A1 (en) * | 2004-09-24 | 2008-11-13 | Mohammad Salman | Muscarinic Receptor Antagonists |
US20090105221A1 (en) * | 2004-09-29 | 2009-04-23 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
US20100016400A1 (en) * | 2004-11-19 | 2010-01-21 | Naresh Kumar | Azabicyclic muscarinic receptor antagonists |
US20100035954A1 (en) * | 2004-12-15 | 2010-02-11 | Mohammad Salman | Acid addition salts of muscarinic receptor antagonists |
US20080319043A1 (en) * | 2005-05-03 | 2008-12-25 | Mohammad Salman | 3,6-Disubstituted Azabicyclo (3.1.0) Hexane Derivatives as Muscarinic Receptor Antagonists |
RU2008119323A (ru) | 2005-10-19 | 2009-11-27 | Рэнбакси Лабораториз Лимитед (In) | Фармацевтические композиции мускаринового рецептора |
US20090010923A1 (en) * | 2007-04-24 | 2009-01-08 | University Of Maryland, Baltimore | Treatment of cancer with anti-muscarinic receptor agents |
MX360640B (es) | 2010-03-01 | 2018-11-09 | Tau Therapeutics Llc Star | Diagnosis e imagenologia de cancer. |
EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
ITRM20110083U1 (it) | 2010-05-13 | 2011-11-14 | De La Cruz Jose Antonio Freire | Piastra per la costruzione di carrelli per aeroplani |
EP2592077A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
SG11201504452WA (en) | 2012-12-18 | 2015-07-30 | Almirall Sa | New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activity |
TWI643853B (zh) | 2013-02-27 | 2018-12-11 | 阿爾米雷爾有限公司 | 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類 |
TWI641373B (zh) | 2013-07-25 | 2018-11-21 | 阿爾米雷爾有限公司 | 具有蕈毒鹼受體拮抗劑和β2腎上腺素受體促效劑二者之活性的2-胺基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽 |
TW201517906A (zh) | 2013-07-25 | 2015-05-16 | Almirall Sa | 含有maba化合物和皮質類固醇之組合 |
TW201617343A (zh) | 2014-09-26 | 2016-05-16 | 阿爾米雷爾有限公司 | 具有β2腎上腺素促效劑及M3蕈毒拮抗劑活性之新穎雙環衍生物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4721783A (en) * | 1986-01-09 | 1988-01-26 | United Pharmaceuticals, Inc. | Anti-spasmodic agents having a heterocyclic ring |
US5278170A (en) * | 1989-04-13 | 1994-01-11 | Beecham Group P.L.C. | Azabicylo oxime compounds |
GB8911080D0 (en) * | 1989-05-15 | 1989-06-28 | Merck Sharp & Dohme | Chemical process |
GB9000305D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Anticholinergic agents |
GB9000301D0 (en) * | 1990-01-06 | 1990-03-07 | Pfizer Ltd | Piperidine & pyrrolidine derivatives |
US5314899A (en) * | 1992-03-03 | 1994-05-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Epibatidine and derivatives, compositions and methods of treating pain |
-
1990
- 1990-09-13 GB GB909020051A patent/GB9020051D0/en active Pending
-
1991
- 1991-09-09 CA CA002068527A patent/CA2068527A1/en not_active Abandoned
- 1991-09-09 US US07/861,876 patent/US5397800A/en not_active Expired - Fee Related
- 1991-09-09 EP EP91916864A patent/EP0510129A1/en not_active Withdrawn
- 1991-09-09 WO PCT/EP1991/001705 patent/WO1992005172A2/en not_active Application Discontinuation
- 1991-09-09 JP JP3515226A patent/JPH07119213B2/ja not_active Expired - Lifetime
- 1991-09-11 PT PT98929A patent/PT98929B/pt not_active IP Right Cessation
- 1991-09-12 IE IE321091A patent/IE913210A1/en unknown
-
1992
- 1992-05-12 FI FI922143A patent/FI922143A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PT98929B (pt) | 1999-02-26 |
WO1992005172A3 (en) | 1992-05-29 |
FI922143A (fi) | 1992-05-12 |
CA2068527A1 (en) | 1992-03-14 |
JPH05501887A (ja) | 1993-04-08 |
WO1992005172A2 (en) | 1992-04-02 |
US5397800A (en) | 1995-03-14 |
IE913210A1 (en) | 1992-02-25 |
EP0510129A1 (en) | 1992-10-28 |
GB9020051D0 (en) | 1990-10-24 |
JPH07119213B2 (ja) | 1995-12-20 |
PT98929A (pt) | 1992-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD | Application lapsed |