FI922014A - Nukleosidderivat. - Google Patents

Nukleosidderivat. Download PDF

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Publication number
FI922014A
FI922014A FI922014A FI922014A FI922014A FI 922014 A FI922014 A FI 922014A FI 922014 A FI922014 A FI 922014A FI 922014 A FI922014 A FI 922014A FI 922014 A FI922014 A FI 922014A
Authority
FI
Finland
Prior art keywords
nukleosidderivat
Prior art date
Application number
FI922014A
Other languages
English (en)
Finnish (fi)
Other versions
FI922014A0 (fi
Inventor
Jo Klaveness
Kjell Undheim
Frode Rise
Jostein Hatlelid
Original Assignee
Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898925037A external-priority patent/GB8925037D0/en
Priority claimed from GB898925039A external-priority patent/GB8925039D0/en
Application filed by Nycomed As filed Critical Nycomed As
Publication of FI922014A publication Critical patent/FI922014A/fi
Publication of FI922014A0 publication Critical patent/FI922014A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI922014A 1989-11-06 1992-05-05 Nukleosidderivat. FI922014A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898925037A GB8925037D0 (en) 1989-11-06 1989-11-06 Nucleoside derivatives
GB898925039A GB8925039D0 (en) 1989-11-06 1989-11-06 Nucleoside derivatives
PCT/EP1990/001853 WO1991006554A1 (en) 1989-11-06 1990-11-06 Nucleoside derivatives

Publications (2)

Publication Number Publication Date
FI922014A true FI922014A (fi) 1992-05-05
FI922014A0 FI922014A0 (fi) 1992-05-05

Family

ID=26296164

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922014A FI922014A0 (fi) 1989-11-06 1992-05-05 Nukleosidderivat.

Country Status (7)

Country Link
EP (1) EP0500610A1 (de)
JP (1) JPH05501404A (de)
AU (1) AU636678B2 (de)
CA (1) CA2073063A1 (de)
FI (1) FI922014A0 (de)
OA (1) OA09697A (de)
WO (1) WO1991006554A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) * 1909-10-07 2002-10-01 Medivir Ab Prodrugs
US5289904A (en) * 1992-08-28 1994-03-01 Harrison Everett W Sound dampener for disk brakes
JPH0692987A (ja) * 1992-09-17 1994-04-05 Tanabe Seiyaku Co Ltd ウリジン誘導体およびその製法
US5717086A (en) * 1993-05-12 1998-02-10 Rhone-Poulenc Chemicals Limited Preparation of fluoro-nucleosides and intermediates for use therein
GB9309795D0 (en) * 1993-05-12 1993-06-23 Rhone Poulenc Chemicals Preparation of flouro-compounds
US6391859B1 (en) 1995-01-27 2002-05-21 Emory University [5-Carboxamido or 5-fluoro]-[2′,3′-unsaturated or 3′-modified]-pyrimidine nucleosides
US5703058A (en) 1995-01-27 1997-12-30 Emory University Compositions containing 5-fluoro-2',3'-didehydro-2',3'-dideoxycytidine or a mono-, di-, or triphosphate thereof and a second antiviral agent
US7635690B2 (en) 1999-01-22 2009-12-22 Emory University HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
US7115584B2 (en) 1999-01-22 2006-10-03 Emory University HIV-1 mutations selected for by β-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine
US6132997A (en) 1999-05-28 2000-10-17 Agilent Technologies Method for linear mRNA amplification
KR20130008546A (ko) 2010-02-15 2013-01-22 닛산 가가쿠 고교 가부시키 가이샤 β-글리코사이드 화합물의 제조 방법
KR20130008547A (ko) * 2010-02-15 2013-01-22 닛산 가가쿠 고교 가부시키 가이샤 β-디하이드로푸란 유도 화합물, β-디하이드로푸란 유도 화합물 또는 β-테트라하이드로푸란 유도 화합물의 제조 방법, β-글리코사이드 화합물, β-글리코사이드 화합물의 제조 방법, 그리고, 4''-에티닐 d4T 및 그 유연 화합물의 제조 방법

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3322747A (en) * 1965-04-01 1967-05-30 Merck & Co Inc Thionocarbonate nucleosides
US3817982A (en) * 1971-12-29 1974-06-18 Syntex Inc 2{40 ,3{40 -unsaturated nucleosides and method of making
EP0254269B1 (de) * 1986-07-21 1993-09-29 Daikin Industries, Limited Polytetrafluoräthylenhaltige Beschichtungsmasse und ihre Verwendung
DD279407A1 (de) * 1986-07-24 1990-06-06 Akad Wissenschaften Ddr Verfahren zur herstellung eines mittels gegen aids
EP0286825A3 (de) * 1987-03-18 1989-04-12 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Verwendung von 3'-fluro-3'-deoxythymidine zur Herstellung von medicamenten zur Behandlung von Viruskrankheiten
WO1988007532A1 (en) * 1987-03-24 1988-10-06 Nycomed A.S. 2',3' dideoxyribofuranoxide derivatives
GB8712115D0 (en) * 1987-05-22 1987-06-24 Hoffmann La Roche Pyrimidine derivatives
EP0294113A1 (de) * 1987-05-29 1988-12-07 The Wellcome Foundation Limited Therapeutische Nucleoside
ZA886890B (en) * 1987-10-09 1989-05-30 Hoffmann La Roche Novel dideoxycytidine derivatives
SE8704298D0 (sv) * 1987-11-03 1987-11-03 Astra Ab Compounds for use in therapy
GB8726136D0 (en) * 1987-11-07 1987-12-09 Wellcome Found Therapeutic nucleosides
ES2075040T3 (es) * 1988-02-16 1995-10-01 Lilly Co Eli 2',3'-dideoxi-2',2'-difluoronucleosidos.
EP0355031A3 (de) * 1988-08-17 1990-12-27 MATTHES, Eckart, Dr. Substituierte Pyrimidinnucleoside, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Mittel
GB8823320D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
GB8823319D0 (en) * 1988-10-05 1988-11-09 Nycomed As Chemical compounds
CA2079796A1 (en) * 1990-04-04 1991-10-05 Jo Klaveness Nucleoside derivatives

Also Published As

Publication number Publication date
OA09697A (en) 1993-08-30
EP0500610A1 (de) 1992-09-02
WO1991006554A1 (en) 1991-05-16
JPH05501404A (ja) 1993-03-18
AU636678B2 (en) 1993-05-06
FI922014A0 (fi) 1992-05-05
AU6619290A (en) 1991-05-31
CA2073063A1 (en) 1991-05-07

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