FI920480A0 - Indolderivat. - Google Patents

Indolderivat.

Info

Publication number
FI920480A0
FI920480A0 FI920480A FI920480A FI920480A0 FI 920480 A0 FI920480 A0 FI 920480A0 FI 920480 A FI920480 A FI 920480A FI 920480 A FI920480 A FI 920480A FI 920480 A0 FI920480 A0 FI 920480A0
Authority
FI
Finland
Prior art keywords
indolderivat
Prior art date
Application number
FI920480A
Other languages
English (en)
Finnish (fi)
Inventor
Hiroshi Nagase
Akira Mizusuna
Yoshihiro Onoda
Koji Kawai
Shu Matsumoto
Takashi Endo
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of FI920480A0 publication Critical patent/FI920480A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Transplantation (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI920480A 1990-06-05 1992-02-04 Indolderivat. FI920480A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP14817990 1990-06-05
JP33545890 1990-11-29
PCT/JP1991/000759 WO1991018901A1 (fr) 1990-06-05 1991-06-05 Derives d'indole

Publications (1)

Publication Number Publication Date
FI920480A0 true FI920480A0 (fi) 1992-02-04

Family

ID=26478480

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920480A FI920480A0 (fi) 1990-06-05 1992-02-04 Indolderivat.

Country Status (9)

Country Link
US (2) US5244904A (es)
EP (2) EP0735026A1 (es)
JP (1) JP3180344B2 (es)
KR (1) KR950002885B1 (es)
CA (2) CA2224047A1 (es)
DE (1) DE69125099T2 (es)
ES (1) ES2098357T3 (es)
FI (1) FI920480A0 (es)
WO (1) WO1991018901A1 (es)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3253077B2 (ja) * 1991-07-05 2002-02-04 スミスクライン・ビーチャム・ファーマシューティチ・ソシエタ・ペル・アチオニ ヒドロイソキノリン誘導体
FR2697850B1 (fr) * 1992-11-10 1994-12-02 Univ Pasteur Nouveaux polypeptides ayant une activité de récepteur opioïde, acides nucléiques codant pour ces polypeptides et utilisations.
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5578725A (en) * 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
CN1163487C (zh) * 1995-07-20 2004-08-25 东丽株式会社 4α-芳基十氢异喹啉化合物及其医药用途
US5994327A (en) * 1995-11-17 1999-11-30 Astra Ab Process for the preparation of morphinans
US7232829B2 (en) * 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
AU2003205332A1 (en) * 2002-01-25 2003-09-02 Philip S. Portoghese Selective analgesic agents
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP1838296B1 (en) * 2004-10-20 2012-08-08 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
SI2118074T1 (sl) 2007-02-01 2014-05-30 Resverlogix Corp. Spojine za preprečevanje in zdravljenje kardiovaskularnih bolezni
PL2346837T3 (pl) 2008-06-26 2015-07-31 Resverlogix Corp Sposoby wytwarzania pochodnych chinazolinonu
US8952021B2 (en) 2009-01-08 2015-02-10 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
CN105859639A (zh) 2009-03-18 2016-08-17 雷斯韦洛吉克斯公司 新的抗炎剂
SI2421533T1 (sl) 2009-04-22 2019-01-31 Resverlogix Corp. Nova protivnetna sredstva
CN103945848B (zh) 2011-11-01 2016-09-07 雷斯韦洛吉克斯公司 被取代的喹唑啉酮的口服即释制剂
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة
MX2020008195A (es) 2018-02-05 2020-11-24 Alkermes Inc Compuestos para el tratamiento del dolor.
US20230146716A1 (en) 2021-10-14 2023-05-11 Biosense Webster (Israel) Ltd. Digital twin of atria for atrial fibrillation patients
US20240020926A1 (en) 2022-07-14 2024-01-18 Biosense Webster (Israel) Ltd. Correcting a segmentation curve in an anatomical model
US20240335169A1 (en) 2023-03-31 2024-10-10 Biosense Webster (Israel) Ltd. Methods and systems for displaying quality profiles points in an electro-anatomical map

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2351599A1 (de) * 1972-07-20 1974-01-31 Du Pont 4a-aryl-trans-decahydrochinoline und verfahren zu ihrer herstellung
US4419517A (en) * 1973-06-01 1983-12-06 E. I. Du Pont De Nemours & Co. 4a-Aryl-trans-decahydroisoquinolines
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
US4310667A (en) * 1976-04-22 1982-01-12 Agence Nationale De Valorisation De La Recherche (Anvar) 2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
US4189583A (en) * 1978-04-26 1980-02-19 The United States Of America As Represented By The Department Of Health, Education And Welfare Synthesis of 4A-aryl-decahydroisoquinolines
FR2436786A1 (fr) * 1978-09-21 1980-04-18 Anvar Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments

Also Published As

Publication number Publication date
JP3180344B2 (ja) 2001-06-25
US5244904A (en) 1993-09-14
US5539119A (en) 1996-07-23
CA2224047A1 (en) 1991-12-06
CA2064853A1 (en) 1991-12-06
DE69125099D1 (de) 1997-04-17
CA2064853C (en) 1999-08-24
EP0485636A1 (en) 1992-05-20
DE69125099T2 (de) 1997-06-19
EP0735026A1 (en) 1996-10-02
KR920702360A (ko) 1992-09-03
EP0485636A4 (en) 1992-11-19
EP0485636B1 (en) 1997-03-12
WO1991018901A1 (fr) 1991-12-12
ES2098357T3 (es) 1997-05-01
KR950002885B1 (ko) 1995-03-28

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Legal Events

Date Code Title Description
FD Application lapsed