FI920480A0 - Indolderivat. - Google Patents

Indolderivat.

Info

Publication number
FI920480A0
FI920480A0 FI920480A FI920480A FI920480A0 FI 920480 A0 FI920480 A0 FI 920480A0 FI 920480 A FI920480 A FI 920480A FI 920480 A FI920480 A FI 920480A FI 920480 A0 FI920480 A0 FI 920480A0
Authority
FI
Finland
Prior art keywords
indolderivat
Prior art date
Application number
FI920480A
Other languages
English (en)
Inventor
Hiroshi Nagase
Akira Mizusuna
Yoshihiro Onoda
Koji Kawai
Shu Matsumoto
Takashi Endo
Original Assignee
Toray Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries filed Critical Toray Industries
Publication of FI920480A0 publication Critical patent/FI920480A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Transplantation (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI920480A 1990-06-05 1992-02-04 Indolderivat. FI920480A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP14817990 1990-06-05
JP33545890 1990-11-29
PCT/JP1991/000759 WO1991018901A1 (fr) 1990-06-05 1991-06-05 Derives d'indole

Publications (1)

Publication Number Publication Date
FI920480A0 true FI920480A0 (fi) 1992-02-04

Family

ID=26478480

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920480A FI920480A0 (fi) 1990-06-05 1992-02-04 Indolderivat.

Country Status (9)

Country Link
US (2) US5244904A (fi)
EP (2) EP0735026A1 (fi)
JP (1) JP3180344B2 (fi)
KR (1) KR950002885B1 (fi)
CA (2) CA2064853C (fi)
DE (1) DE69125099T2 (fi)
ES (1) ES2098357T3 (fi)
FI (1) FI920480A0 (fi)
WO (1) WO1991018901A1 (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0596897B1 (en) * 1991-07-05 2002-03-13 Smithkline Becham S.P.A. Hydroisoquinoline derivatives
FR2697850B1 (fr) 1992-11-10 1994-12-02 Univ Pasteur Nouveaux polypeptides ayant une activité de récepteur opioïde, acides nucléiques codant pour ces polypeptides et utilisations.
US5464841A (en) * 1993-11-08 1995-11-07 Univ Minnesota Use of delta opioid receptor antagonists to treat immunoregulatory disorders
US5578725A (en) * 1995-01-30 1996-11-26 Regents Of The University Of Minnesota Delta opioid receptor antagonists
JP3858273B2 (ja) * 1995-07-20 2006-12-13 東レ株式会社 「4a−アリールデカヒドロイソキノリン化合物およびその医薬用途」
US5994327A (en) * 1995-11-17 1999-11-30 Astra Ab Process for the preparation of morphinans
US7232829B2 (en) * 2001-04-06 2007-06-19 Regents Of The University Of Minnesota Therapeutic compounds and methods
CA2474306A1 (en) * 2002-01-25 2003-08-07 Regents Of The University Of Minnesota Selective analgesic agents
CA2571710A1 (en) 2004-06-24 2006-11-02 Nicholas Valiante Small molecule immunopotentiators and assays for their detection
EP2332527A3 (en) * 2004-10-20 2011-11-16 Resverlogix Corp. Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases
AU2006275514B2 (en) 2005-07-29 2012-04-05 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
PT2118074E (pt) 2007-02-01 2014-03-20 Resverlogix Corp Compostos para a prevenção e tratamento de doenças cardiovasculares
CA2711103C (en) 2008-06-26 2016-08-09 Resverlogix Corp. Methods of preparing quinazolinone derivatives
CA2747417C (en) 2009-01-08 2017-01-03 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
CA3146333A1 (en) 2009-03-18 2010-09-23 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
LT2421533T (lt) 2009-04-22 2018-12-27 Resverlogix Corp. Nauji priešuždegiminiai agentai
JP5992049B2 (ja) 2011-11-01 2016-09-14 レスバーロジックス コーポレイション 置換されたキナゾリノンのための経口速放性製剤
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
WO2016147053A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
WO2019152946A1 (en) 2018-02-05 2019-08-08 Alkermes, Inc. Compounds for the treatment of pain
US20230146716A1 (en) 2021-10-14 2023-05-11 Biosense Webster (Israel) Ltd. Digital twin of atria for atrial fibrillation patients
US20240020926A1 (en) 2022-07-14 2024-01-18 Biosense Webster (Israel) Ltd. Correcting a segmentation curve in an anatomical model

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1024149A (en) * 1972-07-20 1978-01-10 E.I. Du Pont De Nemours And Company 4.alpha.-ARYL-TRANS-DECAHYDROISOQUINOLINES
US4419517A (en) * 1973-06-01 1983-12-06 E. I. Du Pont De Nemours & Co. 4a-Aryl-trans-decahydroisoquinolines
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
US4310667A (en) * 1976-04-22 1982-01-12 Agence Nationale De Valorisation De La Recherche (Anvar) 2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
US4189583A (en) * 1978-04-26 1980-02-19 The United States Of America As Represented By The Department Of Health, Education And Welfare Synthesis of 4A-aryl-decahydroisoquinolines
FR2436786A1 (fr) * 1978-09-21 1980-04-18 Anvar Nouveaux derives des pyrido (4,3-b) carbazoles (ellipticines), substitues en position 1 par une chaine polyaminee, leur obtention et leur application a titre de medicaments

Also Published As

Publication number Publication date
WO1991018901A1 (fr) 1991-12-12
EP0485636A4 (en) 1992-11-19
DE69125099T2 (de) 1997-06-19
US5539119A (en) 1996-07-23
EP0485636B1 (en) 1997-03-12
CA2064853A1 (en) 1991-12-06
CA2064853C (en) 1999-08-24
JP3180344B2 (ja) 2001-06-25
EP0485636A1 (en) 1992-05-20
KR920702360A (ko) 1992-09-03
US5244904A (en) 1993-09-14
CA2224047A1 (en) 1991-12-06
DE69125099D1 (de) 1997-04-17
ES2098357T3 (es) 1997-05-01
KR950002885B1 (ko) 1995-03-28
EP0735026A1 (en) 1996-10-02

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Legal Events

Date Code Title Description
FD Application lapsed