FI913251A0 - Renad kiliarisk neurotrofisk faktor. - Google Patents

Renad kiliarisk neurotrofisk faktor.

Info

Publication number
FI913251A0
FI913251A0 FI913251A FI913251A FI913251A0 FI 913251 A0 FI913251 A0 FI 913251A0 FI 913251 A FI913251 A FI 913251A FI 913251 A FI913251 A FI 913251A FI 913251 A0 FI913251 A0 FI 913251A0
Authority
FI
Finland
Prior art keywords
renad
neurotrophical
kiliarisk
factor
renad kiliarisk
Prior art date
Application number
FI913251A
Other languages
English (en)
Other versions
FI104375B (fi
Inventor
Franklin D Collins
Leu-Fen Lin
Drzislav Mismer
Christine Ko
Original Assignee
Synergen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/293,851 external-priority patent/US5011914A/en
Priority claimed from US07/404,533 external-priority patent/US4997929A/en
Application filed by Synergen Inc filed Critical Synergen Inc
Publication of FI913251A0 publication Critical patent/FI913251A0/fi
Application granted granted Critical
Publication of FI104375B publication Critical patent/FI104375B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Wood Science & Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
FI913251A 1989-01-05 1991-07-04 Menetelmä kiliaarisen neurotroofisen tekijän valmistamiseksi ja sitä koodaavat nukleiinihappojaksot FI104375B (fi)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US29385189 1989-01-05
US07/293,851 US5011914A (en) 1989-01-05 1989-01-05 Purified ciliary neurotrophic factor
US40453389 1989-09-08
US07/404,533 US4997929A (en) 1989-01-05 1989-09-08 Purified ciliary neurotrophic factor
US45856489 1989-12-28
US07/458,564 US5141856A (en) 1989-01-05 1989-12-28 Expression of purified ciliary neurotrophic factor
PCT/US1990/000022 WO1990007341A1 (en) 1989-01-05 1990-01-05 Purified ciliary neurotrophic factor
US9000022 1990-01-05

Publications (2)

Publication Number Publication Date
FI913251A0 true FI913251A0 (fi) 1991-07-04
FI104375B FI104375B (fi) 2000-01-14

Family

ID=27404236

Family Applications (1)

Application Number Title Priority Date Filing Date
FI913251A FI104375B (fi) 1989-01-05 1991-07-04 Menetelmä kiliaarisen neurotroofisen tekijän valmistamiseksi ja sitä koodaavat nukleiinihappojaksot

Country Status (21)

Country Link
US (2) US5141856A (fi)
EP (1) EP0385060B1 (fi)
JP (2) JPH0768270B2 (fi)
KR (1) KR930012105B1 (fi)
AU (1) AU7032496A (fi)
BR (1) BR9006996A (fi)
CH (1) CH681426A5 (fi)
DD (1) DD299318A5 (fi)
DE (1) DE4090006C2 (fi)
DK (1) DK131391A (fi)
ES (1) ES2091768T3 (fi)
FI (1) FI104375B (fi)
GB (1) GB2246132B (fi)
GR (1) GR3021705T3 (fi)
HU (2) HUT58792A (fi)
IE (1) IE81151B1 (fi)
IL (1) IL92958A (fi)
NL (1) NL9020024A (fi)
NZ (1) NZ231985A (fi)
SE (1) SE513358C2 (fi)
WO (1) WO1990007341A1 (fi)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714585A (en) * 1987-10-26 1998-02-03 Sterling Winthrop, Inc. Antibodies that are immunoreactive with interleukin-7
US5328988A (en) * 1987-10-26 1994-07-12 Immunex Corporation Interleukin-7
US5141856A (en) * 1989-01-05 1992-08-25 Synergen, Inc. Expression of purified ciliary neurotrophic factor
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
CN1057295A (zh) * 1990-03-14 1991-12-25 菲迪安股份有限公司 人睫状神经元营养因子，编码该因子的dna序列，以及以重组技术生产该因子
US6511823B1 (en) * 1990-08-20 2003-01-28 American Cyanamid Corporation Heparin binding neurotrophic factor gene sequence
IT1247150B (it) * 1991-01-21 1994-12-12 Fidia Spa Processo per la sintesi e la purificazione del fattore neuronotroficociliare umano (cntf) da escherichia coli.
US5593857A (en) * 1991-08-23 1997-01-14 Scios Inc. Production of homogeneous truncated CNTF
JPH07503128A (ja) * 1991-11-11 1995-04-06 フィディーア・ソシエタ・ペル・アチオニ ヒト毛様体ニューロン親和性因子の先端欠失型および突然変異タンパク質型の合成と精製
US5360740A (en) * 1992-07-02 1994-11-01 Regeneron Pharmaceuticals, Inc. Assay system for degenerative muscle disease
AU6130094A (en) * 1993-01-29 1994-08-15 Regeneron Pharmaceuticals, Inc. Methods of treatment using ciliary neurotrophic factor
EP0632008B1 (en) * 1993-06-01 1998-02-04 Ono Pharmaceutical Co., Ltd. Pentanoic acid derivatives
WO1995022560A1 (en) * 1994-02-22 1995-08-24 The Syntex-Synergen Neuroscience Joint Venture Pharmaceutical formulations of cntf
US6472585B1 (en) 1994-04-25 2002-10-29 Genentech, Inc. Cardiotrophin-1 defective mouse
US7258983B2 (en) * 1994-04-25 2007-08-21 Genentech, Inc. Cardiotrophin-1 compositions and methods for the treatment of tumor
DK0755446T3 (da) * 1994-04-25 2007-01-29 Genentech Inc Cardiotrophin og anvendelser deraf
US5534615A (en) * 1994-04-25 1996-07-09 Genentech, Inc. Cardiac hypertrophy factor and uses therefor
US6743628B1 (en) 1995-08-28 2004-06-01 Washington University Method of cell culture using neurturin
US5739307A (en) * 1995-08-28 1998-04-14 Washington University Polynucleotide encoding neurturin neurotrophic factor
DE69732350T2 (de) 1996-03-14 2005-12-22 Washington University Persephin und verwandte wachstumsfaktoren
US6222022B1 (en) 1996-03-14 2001-04-24 Washington University Persephin and related growth factors
US7015316B1 (en) * 1996-03-14 2006-03-21 Washington University Polynucleotides encoding human persephin and related growth factors
US6299895B1 (en) 1997-03-24 2001-10-09 Neurotech S.A. Device and method for treating ophthalmic diseases
IT1288388B1 (it) * 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
US6042579A (en) * 1997-04-30 2000-03-28 Medtronic, Inc. Techniques for treating neurodegenerative disorders by infusion of nerve growth factors into the brain
US6689573B1 (en) * 1999-05-24 2004-02-10 New England Biolabs, Inc. Method for screening restriction endonucleases
CA2409190A1 (en) 2000-04-14 2001-10-25 The Uab Research Foundation Poliovirus replicons encoding therapeutic agents and uses thereof
WO2005014641A2 (en) * 2003-07-09 2005-02-17 Xencor, Inc. Ciliary neurotrophic factor variants
EP2086555A4 (en) * 2006-10-31 2009-12-23 Univ Ohio State Res Found METHOD AND COMPOSITION FOR INHIBITING ILLNESSES ASSOCIATED WITH GSK-3 IN GLIA CELLS
WO2012075184A2 (en) 2010-12-02 2012-06-07 Neurotech Usa, Inc. Cell lines that secrete anti-angiogenic antibody-scaffolds and soluble receptors and uses thereof
US10456356B2 (en) 2015-05-27 2019-10-29 Neurotech Usa, Inc. Use of encapsulated cell therapy for treatment of ophthalmic disorders

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US458564A (en) * 1891-09-01 Ring-gage
US429517A (en) * 1890-06-03 Packing-box
US293851A (en) * 1884-02-19 de castro
US570651A (en) * 1896-11-03 Motor-driven fan
US404533A (en) * 1889-06-04 Signments
US408172A (en) * 1889-07-30 Steam-boiler house
US4399216A (en) * 1980-02-25 1983-08-16 The Trustees Of Columbia University Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4923696A (en) * 1987-05-04 1990-05-08 Baylor College Of Medicine Method to prepare a neurotrophic composition
US5028622A (en) * 1988-05-06 1991-07-02 Ajinomoto Company, Inc. Administration of amino acids as treatment for neurodegenerative disorders
US5011914A (en) * 1989-01-05 1991-04-30 Collins Franklin D Purified ciliary neurotrophic factor
US4997929A (en) * 1989-01-05 1991-03-05 Synergen, Inc. Purified ciliary neurotrophic factor
US5141856A (en) * 1989-01-05 1992-08-25 Synergen, Inc. Expression of purified ciliary neurotrophic factor
EP0463082A1 (en) * 1989-03-15 1992-01-02 The Regents Of The University Of California Purified ciliary neurotrophic factor
NO911867L (no) * 1989-09-15 1991-07-09 Max Planck Gesellsch Zur Foerd Ciliaer neurotrofisk faktor.
IE903130A1 (en) * 1989-09-15 1991-03-27 Regeneron Pharma Ciliary neurotrophic factor
US5349056A (en) * 1992-10-09 1994-09-20 Regeneron Pharmaceuticals Modified ciliary neurotrophic factors

Also Published As

Publication number Publication date
IE900020L (en) 1990-07-05
SE513358C2 (sv) 2000-08-28
IL92958A0 (en) 1990-09-17
FI104375B (fi) 2000-01-14
WO1990007341A1 (en) 1990-07-12
BR9006996A (pt) 1991-11-12
GB2246132A (en) 1992-01-22
GB9113704D0 (en) 1991-08-21
EP0385060A3 (en) 1991-04-03
AU7032496A (en) 1997-01-16
SE9102079D0 (sv) 1991-07-03
JPH04502916A (ja) 1992-05-28
US5780600A (en) 1998-07-14
HUT58792A (en) 1992-03-30
DD299318A5 (de) 1992-04-09
ES2091768T3 (es) 1996-11-16
NL9020024A (nl) 1991-10-01
IL92958A (en) 1997-09-30
US5141856A (en) 1992-08-25
AU4838190A (en) 1990-08-01
HU211933A9 (en) 1996-01-29
SE9102079L (sv) 1991-07-03
DE4090006C2 (de) 1996-09-19
IE81151B1 (en) 2000-05-03
JPH0768270B2 (ja) 1995-07-26
AU642858B2 (en) 1993-11-04
GB2246132B (en) 1993-09-15
DK131391A (da) 1991-09-05
EP0385060A2 (en) 1990-09-05
KR910700068A (ko) 1991-03-13
GB2246132A8 (en) 2001-05-22
KR930012105B1 (ko) 1993-12-24
NZ231985A (en) 1992-12-23
DK131391D0 (da) 1991-07-05
EP0385060B1 (en) 1996-08-28
CH681426A5 (fi) 1993-03-31
GR3021705T3 (en) 1997-02-28
JPH1129598A (ja) 1999-02-02

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: SYNERGEN, INC.

GB Transfer or assigment of application

Owner name: SYNERGEN, INC.