FI912269A7 - 3'-deamino - 4'deoxi - 4'-amino- 8 -fluorantracykliner och framstaellningsfoerfaranden foer dessa. - Google Patents

3'-deamino - 4'deoxi - 4'-amino- 8 -fluorantracykliner och framstaellningsfoerfaranden foer dessa. Download PDF

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Publication number
FI912269A7
FI912269A7 FI912269A FI912269A FI912269A7 FI 912269 A7 FI912269 A7 FI 912269A7 FI 912269 A FI912269 A FI 912269A FI 912269 A FI912269 A FI 912269A FI 912269 A7 FI912269 A7 FI 912269A7
Authority
FI
Finland
Prior art keywords
fluorantracycliner
deoxi
deamino
och
amino
Prior art date
Application number
FI912269A
Other languages
English (en)
Finnish (fi)
Other versions
FI912269A0 (fi
Inventor
Fabio Animati
Paolo Lombardi
Federico Arcamone
Original Assignee
Menarini Farma Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind filed Critical Menarini Farma Ind
Publication of FI912269A0 publication Critical patent/FI912269A0/fi
Publication of FI912269A7 publication Critical patent/FI912269A7/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/14—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI912269A 1990-05-14 1991-05-10 3'-deamino - 4'deoxi - 4'-amino- 8 -fluorantracykliner och framstaellningsfoerfaranden foer dessa. FI912269A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20300A IT1241927B (it) 1990-05-14 1990-05-14 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono

Publications (2)

Publication Number Publication Date
FI912269A0 FI912269A0 (fi) 1991-05-10
FI912269A7 true FI912269A7 (fi) 1991-11-15

Family

ID=11165542

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912269A FI912269A7 (fi) 1990-05-14 1991-05-10 3'-deamino - 4'deoxi - 4'-amino- 8 -fluorantracykliner och framstaellningsfoerfaranden foer dessa.

Country Status (30)

Country Link
US (1) US5807835A (enExample)
EP (1) EP0457215B1 (enExample)
JP (1) JPH04226972A (enExample)
KR (1) KR910020025A (enExample)
CN (1) CN1031192C (enExample)
AT (1) ATE133177T1 (enExample)
AU (1) AU638574B2 (enExample)
BR (1) BR9101973A (enExample)
CA (1) CA2042463A1 (enExample)
CS (1) CS135891A3 (enExample)
DE (1) DE69116423T2 (enExample)
DK (1) DK0457215T3 (enExample)
ES (1) ES2084724T3 (enExample)
FI (1) FI912269A7 (enExample)
GR (1) GR3018716T3 (enExample)
HU (1) HU209458B (enExample)
IE (1) IE911634A1 (enExample)
IL (1) IL98117A0 (enExample)
IT (1) IT1241927B (enExample)
MA (1) MA22153A1 (enExample)
MX (1) MX25747A (enExample)
NO (1) NO174963C (enExample)
PL (1) PL290236A1 (enExample)
PT (1) PT97663B (enExample)
RO (1) RO108792B1 (enExample)
RU (1) RU2095365C1 (enExample)
TN (1) TNSN91036A1 (enExample)
TW (1) TW228524B (enExample)
YU (1) YU83691A (enExample)
ZA (1) ZA913644B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
IT1271689B (it) * 1994-08-04 1997-06-04 Menarini Farma Ind 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
CN104098628B (zh) * 2014-07-31 2017-07-18 大连大学 一类n‑三氟乙酰柔红霉素的硒代衍生物，其制备方法及应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663445A (en) * 1985-03-20 1987-05-05 The Ohio State Research Foundation 1-fluoro, 4-fluoro, and 1,4-difluoro-2'-halo anthracycline antibiotics
GB8803076D0 (en) * 1988-02-10 1988-03-09 Erba Carlo Spa 3'-deamino-4'-deoxy-4'-amino anthracyclines
GB8902709D0 (en) * 1989-02-07 1989-03-30 Erba Carlo Spa New 4'-epi-4'-amino anthracyclines

Also Published As

Publication number Publication date
MA22153A1 (fr) 1991-12-31
RU2095365C1 (ru) 1997-11-10
CN1056500A (zh) 1991-11-27
GR3018716T3 (en) 1996-04-30
JPH04226972A (ja) 1992-08-17
TW228524B (enExample) 1994-08-21
AU7649391A (en) 1991-11-14
EP0457215B1 (en) 1996-01-17
AU638574B2 (en) 1993-07-01
CS135891A3 (en) 1992-02-19
ZA913644B (en) 1992-02-26
RO108792B1 (ro) 1994-08-30
YU83691A (sh) 1994-01-20
NO174963C (no) 1994-08-10
IL98117A0 (en) 1992-06-21
CN1031192C (zh) 1996-03-06
TNSN91036A1 (fr) 1992-10-25
IT1241927B (it) 1994-02-01
MX25747A (es) 1994-03-31
DE69116423D1 (de) 1996-02-29
PT97663A (pt) 1992-03-31
HUT57227A (en) 1991-11-28
ATE133177T1 (de) 1996-02-15
NO911798D0 (no) 1991-05-08
NO174963B (no) 1994-05-02
HU209458B (en) 1994-06-28
DK0457215T3 (da) 1996-06-10
ES2084724T3 (es) 1996-05-16
BR9101973A (pt) 1991-12-24
US5807835A (en) 1998-09-15
PL290236A1 (en) 1992-07-27
NO911798L (no) 1991-11-15
EP0457215A1 (en) 1991-11-21
DE69116423T2 (de) 1996-06-27
IT9020300A1 (it) 1991-11-14
IT9020300A0 (it) 1990-05-14
KR910020025A (ko) 1991-12-19
IE911634A1 (en) 1991-11-20
PT97663B (pt) 1998-09-30
FI912269A0 (fi) 1991-05-10
CA2042463A1 (en) 1991-11-15

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FD Application lapsed