FI910896A0 - 6-substituerade hexahydrobens (cd) indoler. - Google Patents

6-substituerade hexahydrobens (cd) indoler.

Info

Publication number
FI910896A0
FI910896A0 FI910896A FI910896A FI910896A0 FI 910896 A0 FI910896 A0 FI 910896A0 FI 910896 A FI910896 A FI 910896A FI 910896 A FI910896 A FI 910896A FI 910896 A0 FI910896 A0 FI 910896A0
Authority
FI
Finland
Prior art keywords
indoler
hexahydrobens
substituerade
hexahydrobenz
indoles
Prior art date
Application number
FI910896A
Other languages
English (en)
Other versions
FI102173B (fi
FI910896A (fi
FI102173B1 (fi
Inventor
Thomas Joseph Kress
Marvin Robert Leanna
Michael John Martinelli
Barry Curtis Peterson
Michael Edward Flaugh
Mark Mortensen Foreman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/482,811 external-priority patent/US5204340A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI910896A0 publication Critical patent/FI910896A0/fi
Publication of FI910896A publication Critical patent/FI910896A/fi
Application granted granted Critical
Publication of FI102173B publication Critical patent/FI102173B/fi
Publication of FI102173B1 publication Critical patent/FI102173B1/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/90Benzo [c, d] indoles; Hydrogenated benzo [c, d] indoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI910896A 1990-02-26 1991-02-25 Menetelmä terapeuttisesti käyttökelpoisten heksahydrobents[CD]indolien valmistamiseksi FI102173B1 (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US48519490A 1990-02-26 1990-02-26
US48519490 1990-02-26
US07/482,811 US5204340A (en) 1989-04-11 1990-02-26 Tetrahydrobenz(c,d)indole serotonin agonists
US48281190 1990-02-26
US56798690A 1990-08-15 1990-08-15
US56798690 1990-08-15

Publications (4)

Publication Number Publication Date
FI910896A0 true FI910896A0 (fi) 1991-02-25
FI910896A FI910896A (fi) 1991-08-27
FI102173B FI102173B (fi) 1998-10-30
FI102173B1 FI102173B1 (fi) 1998-10-30

Family

ID=27413631

Family Applications (1)

Application Number Title Priority Date Filing Date
FI910896A FI102173B1 (fi) 1990-02-26 1991-02-25 Menetelmä terapeuttisesti käyttökelpoisten heksahydrobents[CD]indolien valmistamiseksi

Country Status (16)

Country Link
EP (1) EP0444854B1 (fi)
JP (1) JP3135591B2 (fi)
AT (1) ATE143362T1 (fi)
AU (1) AU645779B2 (fi)
BR (1) BR9100769A (fi)
DE (1) DE69122281T2 (fi)
DK (1) DK0444854T3 (fi)
ES (1) ES2094789T3 (fi)
FI (1) FI102173B1 (fi)
GR (1) GR3021930T3 (fi)
HU (1) HU224213B1 (fi)
IE (1) IE76285B1 (fi)
IL (1) IL97308A (fi)
NO (1) NO176757C (fi)
NZ (3) NZ237213A (fi)
PT (1) PT96862B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers
US5229410A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
EP0502418A1 (en) * 1991-02-26 1992-09-09 Basf Corporation Use of levemopamil for the manufacture of a medicament for the treatment of alcohol abuse
CZ285762B6 (cs) * 1993-06-10 1999-11-17 Eli Lilly And Company Farmaceutický prostředek vhodný pro prevenci dávení a zvracení a pro ošetřování sexuální dysfunkce savců a jeho použití
US5990114A (en) * 1996-02-28 1999-11-23 Recordati, S.A., Chemical And Pharmaceutical Company Use of 5-HT1A receptor antagonists for the treatment of urinary incontinence

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL74222A (en) * 1984-02-06 1988-07-31 Lilly Co Eli 6-substituted-4-dialkylamino tetrahydrobenz(c,d)indoles,their preparation and pharmaceutical compositions comprising them
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
TW219933B (fi) * 1990-02-26 1994-02-01 Lilly Co Eli
US5039820A (en) * 1990-02-26 1991-08-13 Eli Lilly And Company 4-amino-6-iodo-hexahydrobenz(cd)indoles
IL97309A (en) * 1990-02-26 1996-11-14 Lilly Co Eli Intermediates for hexahydrobenz] [DC indoles and a process for making their pure enantiomers

Also Published As

Publication number Publication date
ES2094789T3 (es) 1997-02-01
AU645779B2 (en) 1994-01-27
NO176757B (no) 1995-02-13
NO176757C (no) 1995-05-24
FI102173B (fi) 1998-10-30
AU7197091A (en) 1991-08-29
EP0444854B1 (en) 1996-09-25
FI910896A (fi) 1991-08-27
IE910626A1 (en) 1991-08-28
NZ247226A (en) 1994-06-27
BR9100769A (pt) 1991-10-29
ATE143362T1 (de) 1996-10-15
DE69122281T2 (de) 1997-03-06
NZ247227A (en) 1994-06-27
PT96862B (pt) 1998-07-31
IL97308A (en) 1996-10-31
NO910736L (no) 1991-08-27
FI102173B1 (fi) 1998-10-30
IE76285B1 (en) 1997-10-08
NO910736D0 (no) 1991-02-25
NZ237213A (en) 1994-06-27
HU224213B1 (hu) 2005-06-28
GR3021930T3 (en) 1997-03-31
JPH04211654A (ja) 1992-08-03
EP0444854A3 (en) 1992-02-26
IL97308A0 (en) 1992-05-25
PT96862A (pt) 1991-10-31
HUT56541A (en) 1991-09-30
JP3135591B2 (ja) 2001-02-19
EP0444854A2 (en) 1991-09-04
DE69122281D1 (de) 1996-10-31
DK0444854T3 (da) 1996-11-11

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