FI90872C - Förfarande för framställning av terapeutiskt aktiva 1,2,3a,4,5,6-hexahydro/1,3/oxazino/6,5,4-kl/akridinderivat - Google Patents

Förfarande för framställning av terapeutiskt aktiva 1,2,3a,4,5,6-hexahydro/1,3/oxazino/6,5,4-kl/akridinderivat Download PDF

Info

Publication number
FI90872C
FI90872C FI923845A FI923845A FI90872C FI 90872 C FI90872 C FI 90872C FI 923845 A FI923845 A FI 923845A FI 923845 A FI923845 A FI 923845A FI 90872 C FI90872 C FI 90872C
Authority
FI
Finland
Prior art keywords
oxazino
hexahydro
compound
preparation
formula
Prior art date
Application number
FI923845A
Other languages
English (en)
Finnish (fi)
Other versions
FI923845A (sv
FI90872B (sv
FI923845A0 (sv
Inventor
Gregory M Shutske
Kevin J Kapples
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/276,259 external-priority patent/US4927820A/en
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of FI923845A publication Critical patent/FI923845A/sv
Publication of FI923845A0 publication Critical patent/FI923845A0/sv
Application granted granted Critical
Publication of FI90872B publication Critical patent/FI90872B/sv
Publication of FI90872C publication Critical patent/FI90872C/sv

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (3)

1. Forfarande f6r framstållning av terapeutiskt aktiva 1,2,33,4,5,6-hexahydro[1,3]oxaz ino[6,5,4-kl]akri- 5 dinderivat ned formeIn (I) R-- 1° ΓΝ C) (I) vari R år våte eller halogen, och stereoisomerer och farmaceutiskt godtagbara syraadditionssalter darav, k å n -netecknat darav, att en forening med formeln (V) 20 nh2 pH (XX) <v) 25 omsåtts med en forening med formeln Ό” vari R betecknar samma som ovan.
2. Forfarande enligt patentkravet 1, k å η n e -35 tecknat dårav, att man framståller 2-fenyl-l,2,3a,- 4,5,6-hexahydro[l,3]oxazino[6,4,5-kl]akridin eller ett farmaceutiskt godtagbart syraadditionssalt darav.
3. Forfarande enligt patentkravet l, kanne-t e c k n a t darav, att man framstSller 2-(4-fluorfe-5 nyl) -1,2,3a,4,5,6-hexahydro[1,3]oxazino[6,4,5-kl]akridin eller ett farmaceutiskt godtagbart syraadditionssalt darav. I!
FI923845A 1988-11-25 1992-08-27 Förfarande för framställning av terapeutiskt aktiva 1,2,3a,4,5,6-hexahydro/1,3/oxazino/6,5,4-kl/akridinderivat FI90872C (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US27625988 1988-11-25
US07/276,259 US4927820A (en) 1988-11-25 1988-11-25 Fused heterocyclic derivatives of 1,2,3,4-tetrahydroacridine
FI895605A FI90871C (sv) 1988-11-25 1989-11-23 Förfarande för framställning av som läkemedel användbara 3a,4,5,6-tetrahydro-(3H)-pyrimidino/4,5,6-k,1/akridiner
FI895605 1989-11-23

Publications (4)

Publication Number Publication Date
FI923845A FI923845A (sv) 1992-08-27
FI923845A0 FI923845A0 (sv) 1992-08-27
FI90872B FI90872B (sv) 1993-12-31
FI90872C true FI90872C (sv) 1994-04-11

Family

ID=26158655

Family Applications (1)

Application Number Title Priority Date Filing Date
FI923845A FI90872C (sv) 1988-11-25 1992-08-27 Förfarande för framställning av terapeutiskt aktiva 1,2,3a,4,5,6-hexahydro/1,3/oxazino/6,5,4-kl/akridinderivat

Country Status (1)

Country Link
FI (1) FI90872C (sv)

Also Published As

Publication number Publication date
FI923845A (sv) 1992-08-27
FI90872B (sv) 1993-12-31
FI923845A0 (sv) 1992-08-27

Similar Documents

Publication Publication Date Title
DK167250B1 (da) 9-amino-acridinderivater, fremgangsmaade til deres fremstilling, farmaceutiske praeparater deraf og deres anvendelse til fremstilling af laegemidler
JP4109718B2 (ja) アセチルコリンエステラーゼ阻害剤および鎮痛剤としてのイサチン誘導体
CZ398191A3 (en) Novel 4-amino alkyl-2(3h)-indolones and pharmaceutical compositions containing them
PL169392B1 (pl) Sposób wytwarzania nowych pochodnych tetrahydrokarbazolu Twórcy wynalazku:Francis D. King, Harlow, GB Laramie M. Gaster, Harlow, GB Alberto J. Kaumann, Welwyn, GB Rodney Ch. Young, Welwyn, GB PL PL PL PL PL PL PL PL
PT87308B (pt) Processo para a preparacao de n-(piridinil)-1h-indol-1-aminas e de composicoes farmaceuticas que os contem
RU2043989C1 (ru) [(арилалкилпиперидин -4-ил)-метил] -2а,3,4,5- тетрагидро- 1(2н)- аценафтилен -1-оны или их кислотно-аддитивные соли и способ их получения
EP0496314B1 (en) Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[b]indoles and related compounds, intermediates and a process for the preparation thereof and their use as medicaments
FI90872C (sv) Förfarande för framställning av terapeutiskt aktiva 1,2,3a,4,5,6-hexahydro/1,3/oxazino/6,5,4-kl/akridinderivat
US4868177A (en) 1,2,3,4-tetrahydro-1,9-acridinediamines, pharmaceutical compositions and use
IE911744A1 (en) N-substituted trifluoromethylphenyltetrahydropyridines, process for the preparation thereof, intermediates in said process and pharmaceutical compositions containing them
FI90871B (sv) Förfarande för framställning av som läkemedel användbara 3a,4,5,6-tetrahydro-(3H)-pyrimidino/4,5,6-k,1/akridiner
CA2003023C (en) Hydroxy-1,2,3,4-tetrahydroaminoacridines, a process for their preparation and their use as medicaments
IL107001A (en) History of acridinamino and pharmaceutical preparations containing them
EP0401779B1 (en) 4,5,5a,6-Tetrahydro-3H-isoxazolo (5,4,3-kl)acridines derivatives, a process for their preparation and their use as medicaments
US5192789A (en) Substituted 1,2,3,4-tetrahydrocyclopent[b]indoles, 1,2,3,3a,4,8a-hexahydrocyclopent[b]indoles and related compounds
US6100276A (en) Isatin derivatives as acetylcholinesterase inhibitors and analgesics
AU716997C (en) Isatin derivatives as acetylcholinesterase inhibitors and analgesics
IE61413B1 (en) Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl] butyl bridged bicyclic imides
JPH11504616A (ja) ジベンズ[cd,f]インドール誘導体

Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: HOECHST MARION ROUSSEL, INC.