FI906181A - NYA SOCKERDERIVATER, DERAS TILLVERKNINGSMETOD OCH ANVAENDNING. - Google Patents

NYA SOCKERDERIVATER, DERAS TILLVERKNINGSMETOD OCH ANVAENDNING. Download PDF

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Publication number
FI906181A
FI906181A FI906181A FI906181A FI906181A FI 906181 A FI906181 A FI 906181A FI 906181 A FI906181 A FI 906181A FI 906181 A FI906181 A FI 906181A FI 906181 A FI906181 A FI 906181A
Authority
FI
Finland
Prior art keywords
hydrogen atom
alkyl
alkyl group
formula
tillverkningsmetod
Prior art date
Application number
FI906181A
Other languages
Finnish (fi)
Other versions
FI906181A0 (en
Inventor
Ernst Nitsch
Bernhard Lotz
Original Assignee
Laevosan Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laevosan Gmbh & Co Kg filed Critical Laevosan Gmbh & Co Kg
Publication of FI906181A0 publication Critical patent/FI906181A0/en
Publication of FI906181A publication Critical patent/FI906181A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • External Artificial Organs (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Sugar derivatives of the general formula I and II <IMAGE> in which R1 is a hydrogen atom or an alkyl group with 1 to 7 carbon atoms, R2 and R3 are a hydrogen atom or, if R1 is an alkyl group, are also an acyl group R4CO, R is a hydrogen atom or an acyl group R5CO, and R4 and R5 are an alkyl group with 1 to 7 carbon atoms, have an excellent antiproliferative/cytotoxic activity with very low toxicity. The compounds of the formula I and II can be prepared by treating alpha- or beta-1,4-linked di- or oligosaccharides which contain at their reducing end a glucose, fructose or mannose molecule with inorganic or organic bases, isolating in a manner known per se from the resulting reaction mixture the 3-deoxy-D-glyceropentulose (3-DGP) of the formula I in which R1, R2 and R3 are a hydrogen atom, and, if required, converting the 3-DGP in a manner known per se into its glycoside (I, R1 = alkyl, R2, R3 = H), diacylglycoside (I, R1 = alkyl, R2, R3 = R4CO), dianhydride (II, R = H) or diacyl dianhydride (II, R = R5CO).
FI906181A 1989-12-15 1990-12-14 NYA SOCKERDERIVATER, DERAS TILLVERKNINGSMETOD OCH ANVAENDNING. FI906181A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89123301A EP0432309B1 (en) 1989-12-15 1989-12-15 Sugar derivatives, process for their preparation and their use

Publications (2)

Publication Number Publication Date
FI906181A0 FI906181A0 (en) 1990-12-14
FI906181A true FI906181A (en) 1991-06-16

Family

ID=8202239

Family Applications (1)

Application Number Title Priority Date Filing Date
FI906181A FI906181A (en) 1989-12-15 1990-12-14 NYA SOCKERDERIVATER, DERAS TILLVERKNINGSMETOD OCH ANVAENDNING.

Country Status (7)

Country Link
EP (1) EP0432309B1 (en)
AT (1) ATE105294T1 (en)
DE (1) DE58907621D1 (en)
DK (1) DK170171B1 (en)
ES (1) ES2052878T3 (en)
FI (1) FI906181A (en)
NO (1) NO175206C (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2929509B1 (en) * 2008-04-02 2011-01-21 Lvmh Rech USE OF ALKYL GLYCOSIDES OR ALKYL GLYCOSIDE MIXTURES AS AGENTS FOR INHIBITING MICROBIAL GROWTH AND COMPOSITIONS CONTAINING SAID ALKYL GLYCOSIDES

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2609397B1 (en) * 1988-02-23 1991-12-13 Serobiologiques Lab Sa USE OF A CARBOHYDRATE SUBSTANCE OR COMPOSITION AS AN ACTIVE INGREDIENT OF A DERMATOLOGICAL AND / OR COSMETOLOGICAL AND / OR PHARMACEUTICAL AND / OR CELL STIMULANT COMPOSITION, AND COMPOSITION CONTAINING SUCH A CARBON SUBSTANCE OR COMPOSITION

Also Published As

Publication number Publication date
NO175206C (en) 1994-09-14
EP0432309A1 (en) 1991-06-19
DK295490A (en) 1991-06-16
DK170171B1 (en) 1995-06-06
FI906181A0 (en) 1990-12-14
DK295490D0 (en) 1990-12-12
ATE105294T1 (en) 1994-05-15
EP0432309B1 (en) 1994-05-04
NO175206B (en) 1994-06-06
DE58907621D1 (en) 1994-06-09
ES2052878T3 (en) 1994-07-16
NO905417D0 (en) 1990-12-14
NO905417L (en) 1991-06-17

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: LAEVOSAN GESELLSCHAFT M.B.H.