SE8501666D0 - ANTHRACYCLINE DERIVATIVES, PROCEDURES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM - Google Patents

ANTHRACYCLINE DERIVATIVES, PROCEDURES FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM

Info

Publication number
SE8501666D0
SE8501666D0 SE8501666A SE8501666A SE8501666D0 SE 8501666 D0 SE8501666 D0 SE 8501666D0 SE 8501666 A SE8501666 A SE 8501666A SE 8501666 A SE8501666 A SE 8501666A SE 8501666 D0 SE8501666 D0 SE 8501666D0
Authority
SE
Sweden
Prior art keywords
procedures
preparing
pharmaceutical composition
composition containing
anthracycline derivatives
Prior art date
Application number
SE8501666A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE458767B (en
SE8501666L (en
Inventor
Ove Elisson
Sven Bjorkman
Original Assignee
Ove Elisson
Sven Bjorkman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ove Elisson, Sven Bjorkman filed Critical Ove Elisson
Priority to SE8501666A priority Critical patent/SE458767B/en
Publication of SE8501666D0 publication Critical patent/SE8501666D0/en
Publication of SE8501666L publication Critical patent/SE8501666L/en
Publication of SE458767B publication Critical patent/SE458767B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/721—Dextrans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/65—Tetracyclines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran

Abstract

The cpd. of formula (I) is made of dextran molecules on which is coupled at least one anthracyclin cpd. per dextran molecule. R1, R4 = H or hydroxy R2 = H or methoxy, R3 = H or hydroxy or 4'-0-(2,6-dideoxy alpha-L-arbino-hexopyranosyl) gp. Y = H, X = C=O, Z= H. The anthracyclin cpd. is bound to the dextran at the 3-, 4- or 6-position.
SE8501666A 1984-06-05 1985-04-03 Anthracycline derivs. SE458767B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
SE8501666A SE458767B (en) 1984-06-05 1985-04-03 Anthracycline derivs.

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8403004 1984-06-05
SE8501666A SE458767B (en) 1984-06-05 1985-04-03 Anthracycline derivs.

Publications (3)

Publication Number Publication Date
SE8501666D0 true SE8501666D0 (en) 1985-04-03
SE8501666L SE8501666L (en) 1985-12-06
SE458767B SE458767B (en) 1989-05-08

Family

ID=26658737

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8501666A SE458767B (en) 1984-06-05 1985-04-03 Anthracycline derivs.

Country Status (1)

Country Link
SE (1) SE458767B (en)

Also Published As

Publication number Publication date
SE458767B (en) 1989-05-08
SE8501666L (en) 1985-12-06

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