FI902428A0 - Dimeriska epipodofyllotoxinglukosidderivat. - Google Patents

Dimeriska epipodofyllotoxinglukosidderivat.

Info

Publication number
FI902428A0
FI902428A0 FI902428A FI902428A FI902428A0 FI 902428 A0 FI902428 A0 FI 902428A0 FI 902428 A FI902428 A FI 902428A FI 902428 A FI902428 A FI 902428A FI 902428 A0 FI902428 A0 FI 902428A0
Authority
FI
Finland
Prior art keywords
epipodofyllotoxinglukosidderivat
dimerative
dimerative epipodofyllotoxinglukosidderivat
Prior art date
Application number
FI902428A
Other languages
English (en)
Finnish (fi)
Inventor
Mark G Saulnier
David R Langley
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI902428A0 publication Critical patent/FI902428A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI902428A 1989-05-19 1990-05-16 Dimeriska epipodofyllotoxinglukosidderivat. FI902428A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/354,956 US4965348A (en) 1989-05-19 1989-05-19 Dimeric epipodophyllotoxin glucoside derivatives

Publications (1)

Publication Number Publication Date
FI902428A0 true FI902428A0 (fi) 1990-05-16

Family

ID=23395617

Family Applications (1)

Application Number Title Priority Date Filing Date
FI902428A FI902428A0 (fi) 1989-05-19 1990-05-16 Dimeriska epipodofyllotoxinglukosidderivat.

Country Status (9)

Country Link
US (1) US4965348A (pt)
EP (1) EP0398367A3 (pt)
JP (1) JPH035494A (pt)
KR (1) KR920002141B1 (pt)
AU (1) AU625211B2 (pt)
CA (1) CA2013425A1 (pt)
FI (1) FI902428A0 (pt)
PT (1) PT94091A (pt)
ZA (1) ZA903859B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034380A (en) * 1989-11-20 1991-07-23 Bristol-Myers Squibb Company Alkoxymethylidene epipodophyllotoxin glucosides
IT1250692B (it) * 1991-07-23 1995-04-21 Procedimento per la preparazione di demetilepipodofillotossina- beta-d-glucosidi.
US5463040A (en) * 1994-06-28 1995-10-31 Teva Pharmaceutical Industries, Ltd. Method of preparing etoposide
JP3441284B2 (ja) * 1995-03-14 2003-08-25 高砂香料工業株式会社 光学活性アミンの製造方法
US6080396A (en) * 1995-09-29 2000-06-27 Japan Science And Technology Corporation Anthracycline compound derivative and pharmaceutical preparation containing the same
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7342114B2 (en) * 2003-07-01 2008-03-11 California Pacific Medical Center Podophyllotoxin derivatives
US10087194B2 (en) 2015-10-27 2018-10-02 California Pacific Medical Center Podophyllotoxin derivatives and their use
CN106937529B (zh) 2015-10-27 2021-02-05 加州太平洋医疗中心 鬼臼毒素衍生物及其应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6613143A (pt) * 1965-09-21 1967-03-22
CH507934A (de) * 1965-12-14 1971-05-31 Sandoz Ag Verfahren zur Herstellung eines neuen Glucosids
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
US4609644A (en) * 1984-06-15 1986-09-02 St. Jude Children's Research Hospital Epipodophyllotoxinquinone glucoside derivatives, method of production and use
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフイロトキシン誘導体
JPS63150293A (ja) * 1986-12-12 1988-06-22 Nippon Kayaku Co Ltd エトポシド水溶性誘導体
US4916217A (en) * 1987-01-08 1990-04-10 Bristol-Myers Company Phosphorus containing derivatives of epipodophyllotoxin
US4853467A (en) * 1987-05-19 1989-08-01 Bristol-Myers Company Nitrogen containing derivatives of epipodophyllotoxin glucosides
US4874851A (en) * 1987-07-01 1989-10-17 Bristol-Meyers Company 3',4'-dinitrogen substituted epipodophyllotoxin glucoside derivatives
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4868291A (en) * 1987-08-20 1989-09-19 Bristol-Myers Company 4'-deshydroxyepipodophyllotoxin glucosides: synthesis and use
US4888419A (en) * 1987-08-31 1989-12-19 Bristol-Myers Company 3'-demethoxyepipodophyllotoxin glucoside derivatives
ZA886810B (en) * 1987-12-18 1989-08-30 Bristol Myers Co Epipodophyllotoxin glucoside 4'-acyl derivatives
US4912204A (en) * 1988-09-06 1990-03-27 Bristol-Myers Company Fluoro-substituted epipodophyllotoxin glucosides
CN1042362A (zh) * 1988-10-31 1990-05-23 布里斯托尔-米尔斯公司 表鬼臼脂素糖苷的磷酸和磺酸酯的制备方法

Also Published As

Publication number Publication date
KR920002141B1 (ko) 1992-03-12
EP0398367A2 (en) 1990-11-22
KR900018131A (ko) 1990-12-20
US4965348A (en) 1990-10-23
AU625211B2 (en) 1992-07-02
CA2013425A1 (en) 1990-11-19
AU5518390A (en) 1990-11-22
EP0398367A3 (en) 1991-04-10
ZA903859B (en) 1991-01-30
PT94091A (pt) 1991-01-08
JPH035494A (ja) 1991-01-11

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY