FI893475A - Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. - Google Patents

Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. Download PDF

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Publication number
FI893475A
FI893475A FI893475A FI893475A FI893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A
Authority
FI
Finland
Prior art keywords
riktad
endotelceller
anticropp
adhesionreceptor
mot
Prior art date
Application number
FI893475A
Other languages
English (en)
Other versions
FI893475A0 (fi
Inventor
David A Cheresh
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of FI893475A0 publication Critical patent/FI893475A0/fi
Publication of FI893475A publication Critical patent/FI893475A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI893475A 1987-11-19 1989-07-18 Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. FI893475A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12304587A 1987-11-19 1987-11-19
PCT/US1988/004118 WO1989005155A1 (en) 1987-11-19 1988-11-17 Monoclonal antibody against the rgd-directed adhesion receptor of endothelial cells

Publications (2)

Publication Number Publication Date
FI893475A0 FI893475A0 (fi) 1989-07-18
FI893475A true FI893475A (fi) 1989-07-18

Family

ID=22406412

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893475A FI893475A (fi) 1987-11-19 1989-07-18 Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller.

Country Status (5)

Country Link
EP (1) EP0341303A4 (fi)
JP (1) JPH02502156A (fi)
AU (1) AU2807189A (fi)
FI (1) FI893475A (fi)
WO (1) WO1989005155A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5612311A (en) * 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5672585A (en) * 1990-04-06 1997-09-30 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
JP3353209B2 (ja) * 1992-04-03 2002-12-03 ジェネンテク，インコーポレイテッド αｖβ３インテグリンに対する抗体
DE69333209T2 (de) † 1992-10-29 2004-07-01 The Australian National University, Acton Angiogenese-inhibierende antikörper
US5753230A (en) * 1994-03-18 1998-05-19 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
US6056958A (en) * 1994-12-09 2000-05-02 Dupont Pharmaceuticals Method of treatment of arterial and venous thromboembolic disorders
AU733303C (en) 1996-05-31 2002-08-08 Scripps Research Institute, The Methods and compositions useful for inhibition of angiogenesis
DE69828154T2 (de) 1997-03-12 2005-06-23 Smithkline Beecham Corp. Anti-alphavbeta3 humanizierte monoklonale antikörper
WO1998046265A1 (en) * 1997-04-11 1998-10-22 G.D. Searle & Co. Methods for using antagonistic anti-avb3 integrin antibodies
WO1998046264A1 (en) * 1997-04-11 1998-10-22 G.D. Searle & Co. Antagonistic anti-avb3 integrin antibodies
US6160099A (en) * 1998-11-24 2000-12-12 Jonak; Zdenka Ludmila Anti-human αv β3 and αv β5 antibodies
KR20080025174A (ko) 2005-06-23 2008-03-19 메디뮨 인코포레이티드 응집 및 단편화 프로파일이 최적화된 항체 제제
CA2771441C (en) 2009-08-19 2016-10-11 Merck Patent Gmbh Antibodies for the detection of integrin complexes in ffpe material

Also Published As

Publication number Publication date
JPH02502156A (ja) 1990-07-19
AU2807189A (en) 1989-07-05
WO1989005155A1 (en) 1989-06-15
FI893475A0 (fi) 1989-07-18
EP0341303A1 (en) 1989-11-15
EP0341303A4 (en) 1990-06-27

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Legal Events

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MM Patent lapsed

Owner name: SCRIPPS CLINIC AND RESEARCH FOUNDATION