FI893475A - Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. - Google Patents

Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. Download PDF

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Publication number
FI893475A
FI893475A FI893475A FI893475A FI893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A FI 893475 A FI893475 A FI 893475A
Authority
FI
Finland
Prior art keywords
riktad
endotelceller
anticropp
adhesionreceptor
mot
Prior art date
Application number
FI893475A
Other languages
English (en)
Other versions
FI893475A0 (fi
Inventor
David A Cheresh
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of FI893475A publication Critical patent/FI893475A/fi
Publication of FI893475A0 publication Critical patent/FI893475A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI893475A 1987-11-19 1989-07-18 Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller. FI893475A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12304587A 1987-11-19 1987-11-19
PCT/US1988/004118 WO1989005155A1 (en) 1987-11-19 1988-11-17 Monoclonal antibody against the rgd-directed adhesion receptor of endothelial cells

Publications (2)

Publication Number Publication Date
FI893475A true FI893475A (fi) 1989-07-18
FI893475A0 FI893475A0 (fi) 1989-07-18

Family

ID=22406412

Family Applications (1)

Application Number Title Priority Date Filing Date
FI893475A FI893475A0 (fi) 1987-11-19 1989-07-18 Monoklonal antikropp mot en rgd-riktad adhesionreceptor av endotelceller.

Country Status (5)

Country Link
EP (1) EP0341303A4 (fi)
JP (1) JPH02502156A (fi)
AU (1) AU2807189A (fi)
FI (1) FI893475A0 (fi)
WO (1) WO1989005155A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521594B1 (en) 1990-04-06 2003-02-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5612311A (en) * 1990-04-06 1997-03-18 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5672585A (en) * 1990-04-06 1997-09-30 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
US5780303A (en) * 1990-04-06 1998-07-14 La Jolla Cancer Research Foundation Method and composition for treating thrombosis
ATE175241T1 (de) * 1992-04-03 1999-01-15 Genentech Inc Antikörper gegen alpha v beta 3 integrin
SG78239A1 (en) 1992-10-29 2001-02-20 Univ Australian Angiogenesis inhibitory antibodies
US5753230A (en) * 1994-03-18 1998-05-19 The Scripps Research Institute Methods and compositions useful for inhibition of angiogenesis
US6056958A (en) * 1994-12-09 2000-05-02 Dupont Pharmaceuticals Method of treatment of arterial and venous thromboembolic disorders
PT951295E (pt) 1996-05-31 2010-07-29 Scripps Research Inst COMPOSIÎES PARA UTILIZAÆO NA INIBIÆO DE ANGIOGéNESE MEDIADA POR ALFA-V-BETA3
EP0968290B1 (en) * 1997-03-12 2004-12-15 SmithKline Beecham Corporation Anti-alphavbeta3 humanized monoclonal antibodies
JP2001521520A (ja) * 1997-04-11 2001-11-06 ジー.ディー.サール アンド カンパニー 抗α▲下v▼β▲下3▼インテグリン抗体アンタゴニスト
AU6954498A (en) * 1997-04-11 1998-11-11 G.D. Searle & Co. Methods for using antagonistic anti-avb3 integrin antibodies
US6160099A (en) * 1998-11-24 2000-12-12 Jonak; Zdenka Ludmila Anti-human αv β3 and αv β5 antibodies
EP1893647A2 (en) 2005-06-23 2008-03-05 MedImmune, Inc. Antibody formulations having optimized aggregation and fragmentation profiles
PT2467401T (pt) 2009-08-19 2017-04-26 Merck Patent Gmbh Anticorpos para a deteção de complexos de integrina em material ffpe

Also Published As

Publication number Publication date
EP0341303A4 (en) 1990-06-27
JPH02502156A (ja) 1990-07-19
EP0341303A1 (en) 1989-11-15
WO1989005155A1 (en) 1989-06-15
FI893475A0 (fi) 1989-07-18
AU2807189A (en) 1989-07-05

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Legal Events

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MM Patent lapsed

Owner name: SCRIPPS CLINIC AND RESEARCH FOUNDATION