FI883943A0 - Modifierade plasminogen-aktivatorer. - Google Patents

Modifierade plasminogen-aktivatorer.

Info

Publication number
FI883943A0
FI883943A0 FI883943A FI883943A FI883943A0 FI 883943 A0 FI883943 A0 FI 883943A0 FI 883943 A FI883943 A FI 883943A FI 883943 A FI883943 A FI 883943A FI 883943 A0 FI883943 A0 FI 883943A0
Authority
FI
Finland
Prior art keywords
modifications
plasminogen activator
plasminogen
activator
activator modifications
Prior art date
Application number
FI883943A
Other languages
English (en)
Other versions
FI883943A (fi
Inventor
Giovanni Cassani
Francesco Blasi
Federico Maria Robbiati
Marialuisa Nolli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI883943A0 publication Critical patent/FI883943A0/fi
Publication of FI883943A publication Critical patent/FI883943A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
FI883943A 1987-09-07 1988-08-26 Modifierade plasminogen-aktivatorer. FI883943A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721023A GB8721023D0 (en) 1987-09-07 1987-09-07 Modified plasminogen activators

Publications (2)

Publication Number Publication Date
FI883943A0 true FI883943A0 (fi) 1988-08-26
FI883943A FI883943A (fi) 1989-03-08

Family

ID=10623401

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883943A FI883943A (fi) 1987-09-07 1988-08-26 Modifierade plasminogen-aktivatorer.

Country Status (14)

Country Link
EP (1) EP0308716A3 (fi)
JP (1) JPH01117785A (fi)
KR (1) KR890005267A (fi)
CN (1) CN1033070A (fi)
AU (1) AU2196688A (fi)
DK (1) DK491988A (fi)
FI (1) FI883943A (fi)
GB (1) GB8721023D0 (fi)
HU (1) HUT47975A (fi)
IL (1) IL87638A (fi)
NO (1) NO883963L (fi)
NZ (1) NZ226050A (fi)
PT (1) PT88436B (fi)
ZA (1) ZA886401B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098840A (en) * 1986-07-03 1992-03-24 The Green Cross Corporation Human prourokinase mutants
AU5515790A (en) * 1989-05-18 1990-11-22 Green Cross Corporation, The Human prourokinase variants, methods of producing same, dna sequences, plasmids and hosts therefor
CA2025181A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting fungi
JPH0595786A (ja) * 1991-10-07 1993-04-20 Green Cross Corp:The 変異ヒトプロウロキナーゼ
US6120765A (en) * 1993-04-02 2000-09-19 Shiseido Co. Ltd. Urokinase plasminogen activator fragments
WO2006113732A2 (en) 2005-04-19 2006-10-26 Archer-Daniels-Midland Company Soluble non-caloric fiber composition and process of preparing the same
EP2046951B1 (en) 2006-07-05 2011-10-26 Catalyst Biosciences, Inc. Protease screening methods and proteases identified thererby
CA2671971C (en) 2006-12-08 2021-03-30 Attenuon, Llc Urokinase-type plasminogen activator receptor epitope, monoclonal antibodies derived therefrom and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8801374A1 (es) * 1985-04-04 1988-01-01 Beecham Group Plc Un procedimiento para preparar un activante de plasminogeno.
JPH0761266B2 (ja) * 1986-07-03 1995-07-05 株式会社ミドリ十字 変異ヒトプロウロキナ−ゼ
EP0266032A1 (en) * 1986-08-29 1988-05-04 Beecham Group Plc Modified fibrinolytic enzyme
WO1988005822A1 (en) * 1987-01-30 1988-08-11 American Home Products Corporation Des-epidermal growth factor plasminogen activators

Also Published As

Publication number Publication date
FI883943A (fi) 1989-03-08
PT88436A (pt) 1989-07-31
NO883963D0 (no) 1988-09-06
PT88436B (pt) 1992-11-30
NO883963L (no) 1989-03-08
AU2196688A (en) 1989-06-08
CN1033070A (zh) 1989-05-24
EP0308716A3 (en) 1989-06-14
DK491988A (da) 1989-03-08
KR890005267A (ko) 1989-05-13
GB8721023D0 (en) 1987-10-14
IL87638A (en) 1993-04-04
DK491988D0 (da) 1988-09-05
HUT47975A (en) 1989-04-28
JPH01117785A (ja) 1989-05-10
NZ226050A (en) 1991-06-25
EP0308716A2 (en) 1989-03-29
ZA886401B (en) 1989-07-26
IL87638A0 (en) 1989-01-31

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: GRUPPO LEPETIT S.P.A.