FI881653A7 - Menetelmä yksiketjuisen tPA:n ja kaksoisketjuisen tPA:n erottamiseksi toisistaan. - Google Patents

Menetelmä yksiketjuisen tPA:n ja kaksoisketjuisen tPA:n erottamiseksi toisistaan. Download PDF

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Publication number
FI881653A7
FI881653A7 FI881653A FI881653A FI881653A7 FI 881653 A7 FI881653 A7 FI 881653A7 FI 881653 A FI881653 A FI 881653A FI 881653 A FI881653 A FI 881653A FI 881653 A7 FI881653 A7 FI 881653A7
Authority
FI
Finland
Prior art keywords
chain tpa
double
tpa
distinguishing single
chain
Prior art date
Application number
FI881653A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI881653L (fi
FI881653A0 (fi
Inventor
Mitsuyoshi Morii
Masaharu Ohoka
Toshihiko Suzuki
Katsuyuki Suzuki
Nobuhiro Kawashima
Noriko Morii
Kunizo Mori
Original Assignee
Mitsui Toatsu Chemicals Incorporated
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals Incorporated filed Critical Mitsui Toatsu Chemicals Incorporated
Publication of FI881653L publication Critical patent/FI881653L/fi
Publication of FI881653A7 publication Critical patent/FI881653A7/fi
Publication of FI881653A0 publication Critical patent/FI881653A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/814—Enzyme separation or purification
    • Y10S435/815—Enzyme separation or purification by sorption

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Plant Substances (AREA)
FI881653A 1986-08-11 1987-08-10 Foerfarande foer avskiljning av en enkedjad tpa och en dubbelkedjad tpa fraon varandra. FI881653A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP18685086 1986-08-11
JP11597687 1987-05-14
PCT/JP1987/000598 WO1988001294A1 (fr) 1986-08-11 1987-08-10 PROCEDE POUR SEPARER L'UN DE L'AUTRE UN tPA MONO-BRIN ET UN tPA DOUBLE-BRIN

Publications (3)

Publication Number Publication Date
FI881653L FI881653L (fi) 1988-04-08
FI881653A7 true FI881653A7 (fi) 1988-04-08
FI881653A0 FI881653A0 (fi) 1988-04-08

Family

ID=26454387

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881653A FI881653A0 (fi) 1986-08-11 1987-08-10 Foerfarande foer avskiljning av en enkedjad tpa och en dubbelkedjad tpa fraon varandra.

Country Status (9)

Country Link
US (1) US4978620A (OSRAM)
EP (1) EP0276328B1 (OSRAM)
JP (1) JPS6463378A (OSRAM)
AU (1) AU594186B2 (OSRAM)
DE (1) DE3784688D1 (OSRAM)
DK (1) DK196288D0 (OSRAM)
FI (1) FI881653A0 (OSRAM)
NO (1) NO881454L (OSRAM)
WO (1) WO1988001294A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001355A (en) * 1982-12-14 1999-12-14 Dowdle; Eugene Bernard Davey Pro-tPA for the treatment of thrombosis, embolism and related conditions
DE3903581A1 (de) * 1989-02-07 1990-08-16 Boehringer Mannheim Gmbh Gewebs-plasminogenaktivator-derivat
WO1991008303A1 (fr) * 1989-11-28 1991-06-13 Teijin Limited Anticorps contre l'activateur de plasminogene tissulaire bicatenaire humain
US5731186A (en) * 1996-02-05 1998-03-24 Schering Aktiengesellschaft Method for the production of rDSPA α1
JP2002267642A (ja) * 2001-03-13 2002-09-18 Tosoh Corp アルカリ土類金属イオン測定用イオンクロマトグラフィー溶離液およびそれを用いたアルカリ土類金属イオン分析方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU554862B2 (en) * 1982-12-14 1986-09-04 Implico B.V. Plasminogen activator isolated by affinity chromatography
EP0112122B1 (en) * 1982-12-14 1991-08-28 South African Inventions Development Corporation Plasminogen activator
DE3479520D1 (en) * 1983-11-21 1989-09-28 Ciba Geigy Ag Synthesis of tissue plasminogen activator(tpa) by yeast
JPS60168601A (ja) * 1984-02-14 1985-09-02 田之内　寅雄 外周駆動ロ−ラを備えたベニヤレ−スに於ける駆動力伝達装置
JPS6229975A (ja) * 1985-08-01 1987-02-07 Mitsui Toatsu Chem Inc 粗ｔＰＡの精製法
AU606582B2 (en) * 1985-09-06 1991-02-14 Codon Methods for the recovery of tissue plasminogen activator
ATE107664T1 (de) * 1985-10-04 1994-07-15 South African Inventions Reagens und verfahren.
JP3036282B2 (ja) * 1993-02-08 2000-04-24 トヨタ自動車株式会社 ヒータ付き酸素濃度センサ

Also Published As

Publication number Publication date
FI881653L (fi) 1988-04-08
AU594186B2 (en) 1990-03-01
EP0276328A4 (en) 1990-04-10
DK196288A (da) 1988-04-11
DK196288D0 (da) 1988-04-11
EP0276328B1 (en) 1993-03-10
NO881454D0 (no) 1988-04-05
WO1988001294A1 (fr) 1988-02-25
JPS6463378A (en) 1989-03-09
EP0276328A1 (en) 1988-08-03
DE3784688D1 (de) 1993-04-15
FI881653A0 (fi) 1988-04-08
AU7756587A (en) 1988-03-08
NO881454L (no) 1988-04-05
US4978620A (en) 1990-12-18
JPH0556951B2 (OSRAM) 1993-08-20

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: MITSUI TOATSU CHEMICALS, INCORPORATED