FI875438A - Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. - Google Patents

Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. Download PDF

Info

Publication number
FI875438A
FI875438A FI875438A FI875438A FI875438A FI 875438 A FI875438 A FI 875438A FI 875438 A FI875438 A FI 875438A FI 875438 A FI875438 A FI 875438A FI 875438 A FI875438 A FI 875438A
Authority
FI
Finland
Prior art keywords
pyrrolobenzimidazoler
nya
foerfarande foer
foer framstaellning
framstaellning
Prior art date
Application number
FI875438A
Other languages
English (en)
Other versions
FI875438A0 (fi
Inventor
Walter-Gunar Friebe
Alfred Mertens
Klaus Strein
Erwin Boehm
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of FI875438A0 publication Critical patent/FI875438A0/fi
Publication of FI875438A publication Critical patent/FI875438A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI875438A 1986-12-11 1987-12-10 Foerfarande foer framstaellning av nya pyrrolobenzimidazoler. FI875438A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863642315 DE3642315A1 (de) 1986-12-11 1986-12-11 Neue pyrrolobenzimidazole, verfahren zu ihrer herstellung sowie arzneimittel

Publications (2)

Publication Number Publication Date
FI875438A0 FI875438A0 (fi) 1987-12-10
FI875438A true FI875438A (fi) 1988-06-12

Family

ID=6315954

Family Applications (1)

Application Number Title Priority Date Filing Date
FI875438A FI875438A (fi) 1986-12-11 1987-12-10 Foerfarande foer framstaellning av nya pyrrolobenzimidazoler.

Country Status (13)

Country Link
US (1) US4863945A (fi)
EP (1) EP0271040A3 (fi)
JP (1) JPS63162692A (fi)
KR (1) KR880007536A (fi)
AU (1) AU8245087A (fi)
DD (1) DD267047A5 (fi)
DE (1) DE3642315A1 (fi)
DK (1) DK650187A (fi)
FI (1) FI875438A (fi)
HU (1) HU200339B (fi)
IL (1) IL84589A0 (fi)
PT (1) PT86331B (fi)
ZA (1) ZA879166B (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206240A (en) * 1989-12-08 1993-04-27 Merck & Co., Inc. Nitrogen-containing spirocycles
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5434163A (en) * 1993-05-14 1995-07-18 The Medical College Of Pennsylvania Treatment of Cryptococcus neoformans infection
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
US6995162B2 (en) 2001-01-12 2006-02-07 Amgen Inc. Substituted alkylamine derivatives and methods of use
US6878714B2 (en) * 2001-01-12 2005-04-12 Amgen Inc. Substituted alkylamine derivatives and methods of use
EP1598353A1 (en) * 2004-05-17 2005-11-23 Boehringer Ingelheim International GmbH Pyrrolobenzimidazolones and their use as antiproliferative agents
US7285569B2 (en) 2004-09-24 2007-10-23 Hoff Hoffmann-La Roche Inc. Tricycles, their manufacture and use as pharmaceutical agents
US20060142247A1 (en) * 2004-12-17 2006-06-29 Guy Georges Tricyclic heterocycles
AU2006233537A1 (en) * 2005-04-14 2006-10-19 F. Hoffmann-La Roche Ag Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents
WO2006108488A1 (en) * 2005-04-14 2006-10-19 F. Hoffmann-La Roche Ag Tricyclic azole derivatives, their manufacture and use as pharmaceutical agents
WO2007068465A1 (en) * 2005-12-15 2007-06-21 F. Hoffmann-La Roche Ag Tricyclic lactam derivatives, their manufacture and use as pharmaceutical agents
CN101400681A (zh) * 2006-03-23 2009-04-01 霍夫曼-拉罗奇有限公司 取代的吲唑衍生物，它们的制备和作为药剂的应用
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
CN101808994B (zh) * 2007-07-17 2013-05-15 普莱希科公司 用于激酶调节的化合物和方法以及其适应症
MA33028B1 (fr) 2009-04-03 2012-02-01 Plexxikon Inc Compositions et utilisations associees
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
CN102695417A (zh) 2009-11-06 2012-09-26 普莱希科公司 用于激酶调节的化合物和方法及其适应症
BR112013020041B1 (pt) 2011-02-07 2021-11-23 Plexxikon, Inc Compostos e composições para a modulação de quinases e uso dos mesmos
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL147842B1 (en) * 1984-05-12 1989-08-31 Method of obtaining novel pyroisobenzimidazoles
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
PT86331A (de) 1988-01-01
DK650187A (da) 1988-06-12
DE3642315A1 (de) 1988-06-23
PT86331B (pt) 1990-11-07
FI875438A0 (fi) 1987-12-10
DK650187D0 (da) 1987-12-10
AU8245087A (en) 1988-06-16
HUT47278A (en) 1989-02-28
DD267047A5 (de) 1989-04-19
HU200339B (en) 1990-05-28
EP0271040A3 (de) 1989-11-02
JPS63162692A (ja) 1988-07-06
IL84589A0 (en) 1988-04-29
US4863945A (en) 1989-09-05
EP0271040A2 (de) 1988-06-15
ZA879166B (en) 1988-06-14
KR880007536A (ko) 1988-08-27

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Legal Events

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Owner name: BOEHRINGER MANNHEIM GMBH