FI873064A - Stabiliserade oxazafosforinloesningar och foerfarande foer framstaellning av dessa. - Google Patents

Stabiliserade oxazafosforinloesningar och foerfarande foer framstaellning av dessa. Download PDF

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Publication number
FI873064A
FI873064A FI873064A FI873064A FI873064A FI 873064 A FI873064 A FI 873064A FI 873064 A FI873064 A FI 873064A FI 873064 A FI873064 A FI 873064A FI 873064 A FI873064 A FI 873064A
Authority
FI
Finland
Prior art keywords
oxazafosforinloesningar
dessa
stabilizer
foerfarande foer
foer framstaellning
Prior art date
Application number
FI873064A
Other languages
English (en)
Other versions
FI873064A0 (fi
FI86690B (fi
FI86690C (fi
Inventor
Dieter Sauerbier
Klaus Molge
Werner Weigert
Otto Isaac
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of FI873064A0 publication Critical patent/FI873064A0/fi
Publication of FI873064A publication Critical patent/FI873064A/fi
Publication of FI86690B publication Critical patent/FI86690B/fi
Application granted granted Critical
Publication of FI86690C publication Critical patent/FI86690C/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)
  • Cosmetics (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Paper (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
FI873064A 1986-07-11 1987-07-10 Foerfarande foer framstaellning av oxazafosforinloesningar FI86690C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3623369 1986-07-11
DE3623369 1986-07-11

Publications (4)

Publication Number Publication Date
FI873064A0 FI873064A0 (fi) 1987-07-10
FI873064A true FI873064A (fi) 1988-01-12
FI86690B FI86690B (fi) 1992-06-30
FI86690C FI86690C (fi) 1992-10-12

Family

ID=6304930

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873064A FI86690C (fi) 1986-07-11 1987-07-10 Foerfarande foer framstaellning av oxazafosforinloesningar

Country Status (16)

Country Link
US (1) US4952575A (fi)
EP (1) EP0254902B1 (fi)
JP (1) JPS6323888A (fi)
KR (1) KR880001282A (fi)
AT (1) ATE66609T1 (fi)
AU (1) AU598282B2 (fi)
CA (1) CA1289886C (fi)
DE (2) DE3722043A1 (fi)
DK (1) DK168322B1 (fi)
ES (1) ES2038623T3 (fi)
FI (1) FI86690C (fi)
GR (1) GR3002618T3 (fi)
IE (1) IE59897B1 (fi)
IL (1) IL83141A (fi)
PT (1) PT85293B (fi)
ZA (1) ZA875059B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051257A (en) * 1989-05-09 1991-09-24 Pietronigro Dennis D Antineoplastic solution and method for treating neoplasms
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
AU1555099A (en) * 1997-10-13 1999-05-03 Stada Arzneimittel A.G. Liquid presentations of oxazaphosphorine-containing pharmaceutical products
US7205404B1 (en) 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
AUPQ849900A0 (en) * 2000-06-30 2000-07-27 Dbl Australia Pty Ltd. Injectable composition
US6613927B1 (en) 2002-02-08 2003-09-02 American Pharmaceutical Partners, Inc. Sterile lyophilized ifosfamide and associated methods
NZ538584A (en) * 2002-09-05 2007-05-31 Bharat Serums & Vaccines Ltd Stable liquid composition of oxazaphosphorine, mesna and etherified beta-cyclodextrin
US7199111B2 (en) * 2002-12-02 2007-04-03 Bharat Serums & Vaccines Ltd. Aqueous ifosfamide compositions for parenteral administration and a process for their preparations
WO2006030450A2 (en) * 2004-09-13 2006-03-23 Bharat Serums & Vaccines Ltd. Stable emulsion compositions for intravenous administration having antimicrobial preservative efficacy
EP3105238A4 (en) 2014-02-13 2017-11-08 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
BR112016026140A2 (pt) * 2014-05-09 2018-08-07 AuroMedics Pharma LLC formulações de concentrado líquido de ciclofosfamida.
EP3164136A4 (en) 2014-07-02 2018-04-04 Ligand Pharmaceuticals, Inc. Prodrug compounds and uses therof
WO2016005962A2 (en) 2014-07-11 2016-01-14 Dr. Reddy’S Laboratories Limited Stable liquid formulations of cyclophosphamide and processes
US10849916B2 (en) 2014-07-11 2020-12-01 Dr. Reddys Laboratories Limited Stable liquid formulations of cyclophosphamide and its impurities
US10993952B2 (en) * 2015-02-16 2021-05-04 Leiutis Pharmaceuticals Pvt. Ltd. Stable ready to use cyclophosphamide liquid formulations
CN111788196A (zh) 2018-01-09 2020-10-16 配体药物公司 缩醛化合物及其治疗用途
WO2022038072A1 (en) * 2020-08-17 2022-02-24 Sandoz Ag Parenteral pharmaceutical composition comprising cyclophosphamide and a mixture of liquids

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3530147A1 (de) * 1985-08-23 1987-02-26 Bayer Ag Verwendung von diazaphosphorinen zur bekaempfung von endoparasiten

Also Published As

Publication number Publication date
DE3772482D1 (de) 1991-10-02
ATE66609T1 (de) 1991-09-15
ES2038623T3 (es) 1993-08-01
FI873064A0 (fi) 1987-07-10
DK168322B1 (da) 1994-03-14
EP0254902A2 (de) 1988-02-03
PT85293A (de) 1987-08-01
IL83141A0 (en) 1987-12-31
IE871867L (en) 1988-01-11
DK359387D0 (da) 1987-07-10
CA1289886C (en) 1991-10-01
EP0254902B1 (de) 1991-08-28
GR3002618T3 (en) 1993-01-25
IE59897B1 (en) 1994-04-20
AU7554987A (en) 1988-01-14
AU598282B2 (en) 1990-06-21
IL83141A (en) 1992-11-15
US4952575A (en) 1990-08-28
JPS6323888A (ja) 1988-02-01
PT85293B (pt) 1990-03-30
DK359387A (da) 1988-01-12
JPH0543711B2 (fi) 1993-07-02
FI86690B (fi) 1992-06-30
EP0254902A3 (en) 1988-08-03
ZA875059B (en) 1988-02-24
DE3722043A1 (de) 1988-01-14
KR880001282A (ko) 1988-04-22
FI86690C (fi) 1992-10-12

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FG Patent granted

Owner name: ASTA MEDICA AKTIENGESELLSCHAFT

MA Patent expired