FI861379A - Inden- och naftalenderivat. - Google Patents

Inden- och naftalenderivat. Download PDF

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Publication number
FI861379A
FI861379A FI861379A FI861379A FI861379A FI 861379 A FI861379 A FI 861379A FI 861379 A FI861379 A FI 861379A FI 861379 A FI861379 A FI 861379A FI 861379 A FI861379 A FI 861379A
Authority
FI
Finland
Prior art keywords
naftalenderivat
inden
och
och naftalenderivat
Prior art date
Application number
FI861379A
Other languages
English (en)
Other versions
FI82928C (fi
FI82928B (fi
FI861379A0 (fi
Inventor
Robert Thomas Logan
James Redpath
Robert Gibson Roy
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI861379A0 publication Critical patent/FI861379A0/fi
Publication of FI861379A publication Critical patent/FI861379A/fi
Application granted granted Critical
Publication of FI82928B publication Critical patent/FI82928B/fi
Publication of FI82928C publication Critical patent/FI82928C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
    • C07C15/20—Polycyclic condensed hydrocarbons
    • C07C15/24—Polycyclic condensed hydrocarbons containing two rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI861379A 1985-04-02 1986-04-01 Foerfarande foer framstaellning av terapeutiskt aktiva inden- och naftalenderivat. FI82928C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8508588 1985-04-02
GB858508588A GB8508588D0 (en) 1985-04-02 1985-04-02 Indene & napthalene derivatives

Publications (4)

Publication Number Publication Date
FI861379A0 FI861379A0 (fi) 1986-04-01
FI861379A true FI861379A (fi) 1986-10-03
FI82928B FI82928B (fi) 1991-01-31
FI82928C FI82928C (fi) 1991-05-10

Family

ID=10577079

Family Applications (1)

Application Number Title Priority Date Filing Date
FI861379A FI82928C (fi) 1985-04-02 1986-04-01 Foerfarande foer framstaellning av terapeutiskt aktiva inden- och naftalenderivat.

Country Status (14)

Country Link
US (1) US4705782A (fi)
EP (1) EP0199393B1 (fi)
JP (1) JPS61246152A (fi)
KR (1) KR860008111A (fi)
AU (1) AU593793B2 (fi)
CA (1) CA1312871C (fi)
DE (1) DE3661356D1 (fi)
DK (1) DK139286A (fi)
ES (1) ES8800122A1 (fi)
FI (1) FI82928C (fi)
GB (1) GB8508588D0 (fi)
GR (1) GR860779B (fi)
PT (1) PT82319B (fi)
ZA (1) ZA862280B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
US4882354A (en) * 1987-12-16 1989-11-21 Norwich Eaton Pharmaceuticals, Inc. N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents
US4870210A (en) * 1987-12-18 1989-09-26 American Home Products Corporation Aminoguanidine derivative as anti-inflammatory agents
EP0352832B1 (en) * 1988-07-05 1992-05-06 Akzo N.V. Compounds with bronchodilator activity
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents
US5093356A (en) * 1990-01-16 1992-03-03 Merck Frosst Canada, Inc. Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase
US5028629A (en) * 1990-03-28 1991-07-02 Eli Lilly And Company 5-Lipoxygenase inhibitors
US5276052A (en) * 1990-10-26 1994-01-04 Akzo N.V. Use of a benzo[b]thiopene-2-carboximidamide derivative
IE913683A1 (en) * 1990-10-26 1992-05-22 Akzo Nv USE OF A BENZO[b]THIOPHENE-2-CARBOXIMIDAMIDE DERIVATIVE
DE19736921A1 (de) * 1997-08-25 1999-03-04 Bayer Ag Verfahren zur Herstellung von 2-Cyanoindan-1-onen
WO2012149540A1 (en) 2011-04-28 2012-11-01 The Broad Institute Inc Inhibitors of histone deacetylase
CA2880117C (en) 2012-07-27 2021-04-06 The Broad Institute, Inc. Inhibitors of histone deacetylase
US9914717B2 (en) 2012-12-20 2018-03-13 The Broad Institute, Inc. Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB304441A (en) * 1927-12-19 1929-01-24 Ig Farbenindustrie Ag The manufacture of naphthol ether carboxy-amides and aminonaphthol ethers
US3130232A (en) * 1963-02-12 1964-04-21 Upjohn Co Amidinohydrazones of cyclic halovinyl aldehydes
US3530165A (en) * 1967-12-08 1970-09-22 Du Pont Pharmaceutically active 4 - phenylbicyclo(2.2.2)-octane and oct-2-ene-1-carboxamides and derivatives thereof
US3560519A (en) * 1969-03-28 1971-02-02 Sinclair Research Inc Aromatic mono(nitrile carbonates)
US3829467A (en) * 1972-07-03 1974-08-13 Rorer Inc William H Tetrahydronaphthylalkanoic acids and their derivatives
JPS5623982B2 (fi) * 1972-12-07 1981-06-03
US4013682A (en) * 1973-08-03 1977-03-22 Akzona Incorporated N-hydroxy-amidine compounds
CH601166A5 (fi) * 1974-02-14 1978-06-30 Ciba Geigy Ag
NL7407469A (nl) * 1974-06-01 1975-12-03 Akzo Nv Nieuwe amidinohydrazonverbindingen.
DE2620369C3 (de) * 1976-05-08 1979-01-04 Bayer Ag, 5090 Leverkusen Verfahren zur Wiedergewinnung von (l-S)-2-Oxo-bornansulfonat-(10)
DE2804576A1 (de) * 1977-02-15 1978-08-17 Lafon Labor Phenylamidin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE2824409A1 (de) * 1977-06-13 1978-12-21 Degussa 5,6,7-trimethoxy-naphthalin-(2)-carbonsaeure- und -hydronaphthalin-(2)-carbonsaeure-derivate sowie verfahren zu ihrer herstellung
NL7908922A (nl) * 1979-12-12 1981-07-16 Akzo Nv Carboximidamide derivaten.
JPS57179147A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine derivative
DE3360148D1 (en) * 1982-02-10 1985-06-05 Beecham Group Plc Guanidine derivatives
EP0097463A3 (en) * 1982-06-16 1985-05-15 Beecham Group Plc Amidine derivatives
US4661522A (en) * 1984-05-24 1987-04-28 Akzo N.V. Cycloalkane-indene-carboximidamide derivatives
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
US4608390A (en) * 1985-04-26 1986-08-26 Abbott Laboratories Lipoxygenase inhibiting compounds
US4605669A (en) * 1985-04-26 1986-08-12 Abbott Laboratories Lipoxygenase inhibiting naphthohydroxamic acids

Also Published As

Publication number Publication date
JPS61246152A (ja) 1986-11-01
FI82928C (fi) 1991-05-10
PT82319B (pt) 1988-03-03
GB8508588D0 (en) 1985-05-09
DK139286D0 (da) 1986-03-25
EP0199393B1 (en) 1988-12-07
US4705782A (en) 1987-11-10
PT82319A (en) 1986-05-01
AU593793B2 (en) 1990-02-22
ZA862280B (en) 1986-11-26
ES553601A0 (es) 1987-10-16
ES8800122A1 (es) 1987-10-16
DE3661356D1 (de) 1989-01-12
FI82928B (fi) 1991-01-31
DK139286A (da) 1986-10-03
GR860779B (en) 1986-06-24
AU5539686A (en) 1986-10-16
CA1312871C (en) 1993-01-19
KR860008111A (ko) 1986-11-12
FI861379A0 (fi) 1986-04-01
EP0199393A1 (en) 1986-10-29

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Legal Events

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MM Patent lapsed
MM Patent lapsed

Owner name: AKZO N.V.