DK139286A - Inden- og naphthalenderivater - Google Patents
Inden- og naphthalenderivater Download PDFInfo
- Publication number
- DK139286A DK139286A DK139286A DK139286A DK139286A DK 139286 A DK139286 A DK 139286A DK 139286 A DK139286 A DK 139286A DK 139286 A DK139286 A DK 139286A DK 139286 A DK139286 A DK 139286A
- Authority
- DK
- Denmark
- Prior art keywords
- naphthalender
- derivatives
- naphthalender derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C15/00—Cyclic hydrocarbons containing only six-membered aromatic rings as cyclic parts
- C07C15/20—Polycyclic condensed hydrocarbons
- C07C15/24—Polycyclic condensed hydrocarbons containing two rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
- C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
- C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
- C07C239/08—Hydroxylamino compounds or their ethers or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
- C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858508588A GB8508588D0 (en) | 1985-04-02 | 1985-04-02 | Indene & napthalene derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK139286D0 DK139286D0 (da) | 1986-03-25 |
| DK139286A true DK139286A (da) | 1986-10-03 |
Family
ID=10577079
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK139286A DK139286A (da) | 1985-04-02 | 1986-03-25 | Inden- og naphthalenderivater |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4705782A (fi) |
| EP (1) | EP0199393B1 (fi) |
| JP (1) | JPS61246152A (fi) |
| KR (1) | KR860008111A (fi) |
| AU (1) | AU593793B2 (fi) |
| CA (1) | CA1312871C (fi) |
| DE (1) | DE3661356D1 (fi) |
| DK (1) | DK139286A (fi) |
| ES (1) | ES8800122A1 (fi) |
| FI (1) | FI82928C (fi) |
| GB (1) | GB8508588D0 (fi) |
| GR (1) | GR860779B (fi) |
| PT (1) | PT82319B (fi) |
| ZA (1) | ZA862280B (fi) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4661522A (en) * | 1984-05-24 | 1987-04-28 | Akzo N.V. | Cycloalkane-indene-carboximidamide derivatives |
| US4882354A (en) * | 1987-12-16 | 1989-11-21 | Norwich Eaton Pharmaceuticals, Inc. | N-hydroxy-5-phenyl-2-furancarboximidamides useful as cardiotonic agents |
| US4870210A (en) * | 1987-12-18 | 1989-09-26 | American Home Products Corporation | Aminoguanidine derivative as anti-inflammatory agents |
| DE68901424D1 (de) * | 1988-07-05 | 1992-06-11 | Akzo Nv | Verbindungen mit bronchodilatatorischer aktivitaet. |
| US4981865A (en) * | 1989-05-26 | 1991-01-01 | Warner-Lambert Co. | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents |
| US5093356A (en) * | 1990-01-16 | 1992-03-03 | Merck Frosst Canada, Inc. | Indenyl hydroxamic acids and hydroxy ureas as inhibitors of 5-lipoxygenase |
| US5028629A (en) * | 1990-03-28 | 1991-07-02 | Eli Lilly And Company | 5-Lipoxygenase inhibitors |
| IE913683A1 (en) * | 1990-10-26 | 1992-05-22 | Akzo Nv | USE OF A BENZO[b]THIOPHENE-2-CARBOXIMIDAMIDE DERIVATIVE |
| US5276052A (en) * | 1990-10-26 | 1994-01-04 | Akzo N.V. | Use of a benzo[b]thiopene-2-carboximidamide derivative |
| DE19736921A1 (de) * | 1997-08-25 | 1999-03-04 | Bayer Ag | Verfahren zur Herstellung von 2-Cyanoindan-1-onen |
| JP6240063B2 (ja) | 2011-04-28 | 2017-11-29 | ザ ブロード インスティテュート， インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| JP6337255B2 (ja) | 2012-07-27 | 2018-06-06 | ザ ブロード インスティテュート, インコーポレーテッドThe Broad Institute, Inc. | ヒストンデアセチラーゼの阻害剤 |
| WO2014100438A1 (en) | 2012-12-20 | 2014-06-26 | The Broad Institute, Inc. | Cycloalkenyl hydroxamic acid derivatives and their use as histone deacetylase inhibitors |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB304441A (en) * | 1927-12-19 | 1929-01-24 | Ig Farbenindustrie Ag | The manufacture of naphthol ether carboxy-amides and aminonaphthol ethers |
| US3130232A (en) * | 1963-02-12 | 1964-04-21 | Upjohn Co | Amidinohydrazones of cyclic halovinyl aldehydes |
| US3530165A (en) * | 1967-12-08 | 1970-09-22 | Du Pont | Pharmaceutically active 4 - phenylbicyclo(2.2.2)-octane and oct-2-ene-1-carboxamides and derivatives thereof |
| US3560519A (en) * | 1969-03-28 | 1971-02-02 | Sinclair Research Inc | Aromatic mono(nitrile carbonates) |
| US3829467A (en) * | 1972-07-03 | 1974-08-13 | Rorer Inc William H | Tetrahydronaphthylalkanoic acids and their derivatives |
| JPS5623982B2 (fi) * | 1972-12-07 | 1981-06-03 | ||
| US4013682A (en) * | 1973-08-03 | 1977-03-22 | Akzona Incorporated | N-hydroxy-amidine compounds |
| CH601166A5 (fi) * | 1974-02-14 | 1978-06-30 | Ciba Geigy Ag | |
| NL7407469A (nl) * | 1974-06-01 | 1975-12-03 | Akzo Nv | Nieuwe amidinohydrazonverbindingen. |
| DE2620369C3 (de) * | 1976-05-08 | 1979-01-04 | Bayer Ag, 5090 Leverkusen | Verfahren zur Wiedergewinnung von (l-S)-2-Oxo-bornansulfonat-(10) |
| DE2804576A1 (de) * | 1977-02-15 | 1978-08-17 | Lafon Labor | Phenylamidin-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen |
| DE2824409A1 (de) * | 1977-06-13 | 1978-12-21 | Degussa | 5,6,7-trimethoxy-naphthalin-(2)-carbonsaeure- und -hydronaphthalin-(2)-carbonsaeure-derivate sowie verfahren zu ihrer herstellung |
| NL7908922A (nl) * | 1979-12-12 | 1981-07-16 | Akzo Nv | Carboximidamide derivaten. |
| JPS57179147A (en) * | 1981-04-28 | 1982-11-04 | Torii Yakuhin Kk | Amidine derivative |
| DE3360148D1 (en) * | 1982-02-10 | 1985-06-05 | Beecham Group Plc | Guanidine derivatives |
| EP0097463A3 (en) * | 1982-06-16 | 1985-05-15 | Beecham Group Plc | Amidine derivatives |
| US4661522A (en) * | 1984-05-24 | 1987-04-28 | Akzo N.V. | Cycloalkane-indene-carboximidamide derivatives |
| US4604407A (en) * | 1985-04-04 | 1986-08-05 | E. R. Squibb & Sons, Inc. | Hydroxamates |
| US4605669A (en) * | 1985-04-26 | 1986-08-12 | Abbott Laboratories | Lipoxygenase inhibiting naphthohydroxamic acids |
| US4608390A (en) * | 1985-04-26 | 1986-08-26 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
-
1985
- 1985-04-02 GB GB858508588A patent/GB8508588D0/en active Pending
-
1986
- 1986-03-24 DE DE8686200495T patent/DE3661356D1/de not_active Expired
- 1986-03-24 EP EP86200495A patent/EP0199393B1/en not_active Expired
- 1986-03-25 DK DK139286A patent/DK139286A/da not_active Application Discontinuation
- 1986-03-26 US US06/844,146 patent/US4705782A/en not_active Expired - Fee Related
- 1986-03-26 ZA ZA862280A patent/ZA862280B/xx unknown
- 1986-03-26 GR GR860779A patent/GR860779B/el unknown
- 1986-03-26 CA CA000505094A patent/CA1312871C/en not_active Expired - Fee Related
- 1986-04-01 KR KR1019860002448A patent/KR860008111A/ko not_active Application Discontinuation
- 1986-04-01 AU AU55396/86A patent/AU593793B2/en not_active Ceased
- 1986-04-01 JP JP61075404A patent/JPS61246152A/ja active Pending
- 1986-04-01 PT PT82319A patent/PT82319B/pt not_active IP Right Cessation
- 1986-04-01 FI FI861379A patent/FI82928C/fi not_active IP Right Cessation
- 1986-04-01 ES ES553601A patent/ES8800122A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| US4705782A (en) | 1987-11-10 |
| ES8800122A1 (es) | 1987-10-16 |
| DE3661356D1 (de) | 1989-01-12 |
| GB8508588D0 (en) | 1985-05-09 |
| FI861379A (fi) | 1986-10-03 |
| EP0199393A1 (en) | 1986-10-29 |
| KR860008111A (ko) | 1986-11-12 |
| CA1312871C (en) | 1993-01-19 |
| FI82928B (fi) | 1991-01-31 |
| ZA862280B (en) | 1986-11-26 |
| EP0199393B1 (en) | 1988-12-07 |
| DK139286D0 (da) | 1986-03-25 |
| ES553601A0 (es) | 1987-10-16 |
| JPS61246152A (ja) | 1986-11-01 |
| PT82319B (pt) | 1988-03-03 |
| AU593793B2 (en) | 1990-02-22 |
| PT82319A (en) | 1986-05-01 |
| FI861379A0 (fi) | 1986-04-01 |
| AU5539686A (en) | 1986-10-16 |
| GR860779B (en) | 1986-06-24 |
| FI82928C (fi) | 1991-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PUP | Patent expired | ||
| AHB | Application shelved due to non-payment |