FI85194C - Bestaemning av kliniska parametrar med hjaelp av en enzymatisk immunoprocess. - Google Patents
Bestaemning av kliniska parametrar med hjaelp av en enzymatisk immunoprocess. Download PDFInfo
- Publication number
- FI85194C FI85194C FI873398A FI873398A FI85194C FI 85194 C FI85194 C FI 85194C FI 873398 A FI873398 A FI 873398A FI 873398 A FI873398 A FI 873398A FI 85194 C FI85194 C FI 85194C
- Authority
- FI
- Finland
- Prior art keywords
- antigen
- zone
- enzyme
- antibody
- labeled
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 title claims description 7
- 239000000427 antigen Substances 0.000 claims description 72
- 102000036639 antigens Human genes 0.000 claims description 71
- 108091007433 antigens Proteins 0.000 claims description 71
- 102000004190 Enzymes Human genes 0.000 claims description 54
- 108090000790 Enzymes Proteins 0.000 claims description 54
- 238000000034 method Methods 0.000 claims description 37
- 239000003593 chromogenic compound Substances 0.000 claims description 23
- 238000006243 chemical reaction Methods 0.000 claims description 16
- 239000013060 biological fluid Substances 0.000 claims description 15
- 239000000463 material Substances 0.000 claims description 15
- 238000003556 assay Methods 0.000 claims description 11
- 239000007787 solid Substances 0.000 claims description 11
- 239000000126 substance Substances 0.000 claims description 9
- 230000000295 complement effect Effects 0.000 claims description 7
- 239000011521 glass Substances 0.000 claims description 7
- 241000700605 Viruses Species 0.000 claims description 6
- 239000000758 substrate Substances 0.000 claims description 6
- 108060003951 Immunoglobulin Proteins 0.000 claims description 5
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical class O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 5
- 108010011834 Streptolysins Proteins 0.000 claims description 5
- 150000001875 compounds Chemical class 0.000 claims description 5
- 102000018358 immunoglobulin Human genes 0.000 claims description 5
- 239000000813 peptide hormone Substances 0.000 claims description 5
- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims description 4
- 239000000969 carrier Substances 0.000 claims description 4
- 239000012530 fluid Substances 0.000 claims description 4
- 229940072221 immunoglobulins Drugs 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 4
- 238000000926 separation method Methods 0.000 claims description 4
- 239000005995 Aluminium silicate Substances 0.000 claims description 3
- 239000005909 Kieselgur Substances 0.000 claims description 3
- 229910010413 TiO 2 Inorganic materials 0.000 claims description 3
- 235000012211 aluminium silicate Nutrition 0.000 claims description 3
- 238000004458 analytical method Methods 0.000 claims description 3
- -1 i) the antibodies Proteins 0.000 claims description 3
- 230000002452 interceptive effect Effects 0.000 claims description 3
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 3
- 229910052751 metal Inorganic materials 0.000 claims description 3
- 239000002184 metal Substances 0.000 claims description 3
- 150000002739 metals Chemical class 0.000 claims description 3
- 229920000642 polymer Polymers 0.000 claims description 3
- 229920005862 polyol Polymers 0.000 claims description 3
- 150000003077 polyols Chemical class 0.000 claims description 3
- 108090000623 proteins and genes Proteins 0.000 claims description 3
- ZFFFJLDTCLJDHL-JQYCEVDMSA-N Pregnanediol-3-glucuronide Chemical compound O([C@H]1C[C@H]2CC[C@H]3[C@@H]4CC[C@@H]([C@]4(CC[C@@H]3[C@@]2(C)CC1)C)[C@@H](O)C)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O ZFFFJLDTCLJDHL-JQYCEVDMSA-N 0.000 claims description 2
- 229920002472 Starch Polymers 0.000 claims description 2
- 229920002678 cellulose Polymers 0.000 claims description 2
- 239000001913 cellulose Substances 0.000 claims description 2
- FJAZVHYPASAQKM-JBAURARKSA-N estrone 3-O-(beta-D-glucuronide) Chemical compound C([C@@H]1[C@@H](C2=CC=3)CC[C@]4([C@H]1CCC4=O)C)CC2=CC=3O[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O FJAZVHYPASAQKM-JBAURARKSA-N 0.000 claims description 2
- 150000004676 glycans Chemical class 0.000 claims description 2
- 239000008187 granular material Substances 0.000 claims description 2
- 239000005556 hormone Substances 0.000 claims description 2
- 229940088597 hormone Drugs 0.000 claims description 2
- 239000003456 ion exchange resin Substances 0.000 claims description 2
- 229920003303 ion-exchange polymer Polymers 0.000 claims description 2
- 229920001282 polysaccharide Polymers 0.000 claims description 2
- 239000005017 polysaccharide Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- ZFFFJLDTCLJDHL-UHFFFAOYSA-N pregnanediol glucuronide Natural products C1CC2(C)C3CCC4(C)C(C(O)C)CCC4C3CCC2CC1OC1OC(C(O)=O)C(O)C(O)C1O ZFFFJLDTCLJDHL-UHFFFAOYSA-N 0.000 claims description 2
- 229960003387 progesterone Drugs 0.000 claims description 2
- 239000000186 progesterone Substances 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 235000019698 starch Nutrition 0.000 claims description 2
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims 4
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims 4
- 239000003270 steroid hormone Substances 0.000 claims 4
- 239000012491 analyte Substances 0.000 claims 2
- 239000010408 film Substances 0.000 claims 2
- 239000004408 titanium dioxide Substances 0.000 claims 2
- 108091005804 Peptidases Proteins 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 claims 1
- 108010046334 Urease Proteins 0.000 claims 1
- 239000012876 carrier material Substances 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 238000013375 chromatographic separation Methods 0.000 claims 1
- 210000003743 erythrocyte Anatomy 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 239000004005 microsphere Substances 0.000 claims 1
- 239000007800 oxidant agent Substances 0.000 claims 1
- 230000001590 oxidative effect Effects 0.000 claims 1
- 239000008107 starch Substances 0.000 claims 1
- 239000012780 transparent material Substances 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
- 102000013415 peroxidase activity proteins Human genes 0.000 description 9
- 108040007629 peroxidase activity proteins Proteins 0.000 description 9
- 210000002700 urine Anatomy 0.000 description 5
- 238000003018 immunoassay Methods 0.000 description 4
- 229920000915 polyvinyl chloride Polymers 0.000 description 4
- 239000004800 polyvinyl chloride Substances 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000012631 diagnostic technique Methods 0.000 description 3
- 230000000984 immunochemical effect Effects 0.000 description 3
- 238000002965 ELISA Methods 0.000 description 2
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 2
- 108010093096 Immobilized Enzymes Proteins 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 238000001042 affinity chromatography Methods 0.000 description 2
- 239000000872 buffer Substances 0.000 description 2
- 150000002148 esters Chemical class 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 238000011534 incubation Methods 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- 238000001179 sorption measurement Methods 0.000 description 2
- YRNWIFYIFSBPAU-UHFFFAOYSA-N 4-[4-(dimethylamino)phenyl]-n,n-dimethylaniline Chemical compound C1=CC(N(C)C)=CC=C1C1=CC=C(N(C)C)C=C1 YRNWIFYIFSBPAU-UHFFFAOYSA-N 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 102000002260 Alkaline Phosphatase Human genes 0.000 description 1
- 108020004774 Alkaline Phosphatase Proteins 0.000 description 1
- 235000009161 Espostoa lanata Nutrition 0.000 description 1
- 240000001624 Espostoa lanata Species 0.000 description 1
- 241000598436 Human T-cell lymphotropic virus Species 0.000 description 1
- 239000004677 Nylon Substances 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 239000005062 Polybutadiene Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 229920005654 Sephadex Polymers 0.000 description 1
- 239000012507 Sephadex™ Substances 0.000 description 1
- 229920002684 Sepharose Polymers 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 230000004520 agglutination Effects 0.000 description 1
- 238000010420 art technique Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 102000005936 beta-Galactosidase Human genes 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 210000000601 blood cell Anatomy 0.000 description 1
- 239000001045 blue dye Substances 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 239000013522 chelant Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 229910001385 heavy metal Inorganic materials 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- PGXWDLGWMQIXDT-UHFFFAOYSA-N methylsulfinylmethane;hydrate Chemical compound O.CS(C)=O PGXWDLGWMQIXDT-UHFFFAOYSA-N 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920001778 nylon Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920002857 polybutadiene Polymers 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000013517 stratification Methods 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 241001529453 unidentified herpesvirus Species 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54391—Immunochromatographic test strips based on vertical flow
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1944385 | 1985-02-08 | ||
IT19443/85A IT1200382B (it) | 1985-02-08 | 1985-02-08 | Sistema di rilevazione e/o dosaggio di parametri clinici per via immuno enzimatica |
EP8600055 | 1986-02-02 | ||
PCT/EP1986/000055 WO1986004683A1 (en) | 1985-02-08 | 1986-02-02 | Determination of clinical parameters by enzyme immunoprocess |
Publications (4)
Publication Number | Publication Date |
---|---|
FI873398A FI873398A (fi) | 1987-08-05 |
FI873398A0 FI873398A0 (fi) | 1987-08-05 |
FI85194B FI85194B (fi) | 1991-11-29 |
FI85194C true FI85194C (fi) | 1992-03-10 |
Family
ID=11158028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI873398A FI85194C (fi) | 1985-02-08 | 1987-08-05 | Bestaemning av kliniska parametrar med hjaelp av en enzymatisk immunoprocess. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0243370A1 (es) |
JP (1) | JPS62501989A (es) |
AU (1) | AU5511886A (es) |
DD (1) | DD245727A5 (es) |
ES (5) | ES8802256A1 (es) |
FI (1) | FI85194C (es) |
HU (1) | HUT56632A (es) |
IT (1) | IT1200382B (es) |
MW (1) | MW5287A1 (es) |
OA (1) | OA08640A (es) |
RO (1) | RO100056A2 (es) |
WO (1) | WO1986004683A1 (es) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806311A (en) * | 1985-08-28 | 1989-02-21 | Miles Inc. | Multizone analytical element having labeled reagent concentration zone |
US4959305A (en) * | 1986-06-18 | 1990-09-25 | Miles Inc. | Reversible immobilization of assay reagents in a multizone test device |
CA1289872C (en) * | 1986-06-18 | 1991-10-01 | David L. Woodrum | Reversible immobilization of assay reagents in a multizone test device |
ES2004066A6 (es) * | 1987-01-21 | 1988-12-01 | Euro Fassel Aktiebolag | Metodo para analisis cualitativo y-o cuantitativo de antigenos,anticuerpos yno microorganismos u otras celulas y su correspondiente equipo |
AU592174B2 (en) * | 1987-02-17 | 1990-01-04 | Genesis Labs, Inc. | Immunoassay test strip |
AU586552B2 (en) * | 1987-02-25 | 1989-07-13 | Genesis Labs, Inc. | Dry test strip for devices using oxygen demanding detection system |
DE291194T1 (de) * | 1987-04-27 | 1992-03-19 | Unilever N.V., Rotterdam | Immunoassays und vorrichtungen dafuer. |
DE3878820T2 (de) * | 1987-04-29 | 1993-07-22 | Celltech Ltd | Vorrichtung fuer bindungstest. |
US5641639A (en) * | 1987-04-29 | 1997-06-24 | Celltech Therapeutics Limited | Binding assay device |
IT1223295B (it) * | 1987-08-14 | 1990-09-19 | Boehringer Biochemia Srl | Dispositivo e metodo immunodiagnostico |
FR2621393B1 (fr) * | 1987-10-05 | 1991-12-13 | Toledano Jacques | Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique |
US5334513A (en) * | 1988-05-17 | 1994-08-02 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5039607A (en) * | 1988-05-17 | 1991-08-13 | Syntex (U.S.A.) Inc. | Method for immunochromatographic analysis |
US5338513A (en) * | 1988-07-30 | 1994-08-16 | Boehringer Mannheim Gmbh | Test carrier for the analytical determination of a component of a liquid sample |
FR2634891B1 (fr) * | 1988-08-01 | 1994-05-06 | Biotrol Laboratoires | Procede et dispositif pour la determination qualitative et/ou quantitative d'un ligand dans un fluide |
US5079174A (en) * | 1988-12-08 | 1992-01-07 | Boehringer Mannheim Corporation | Apparatus for sequential determination of an analyte in a fluid sample |
DE3842702A1 (de) * | 1988-12-19 | 1990-06-21 | Boehringer Mannheim Gmbh | Testtraeger zur analytischen untersuchung einer probenfluessigkeit mit hilfe einer spezifischen bindungsreaktion zweier bioaffiner bindungspartner und entsprechendes testverfahren |
GB8903627D0 (en) * | 1989-02-17 | 1989-04-05 | Unilever Plc | Assays |
AU2247192A (en) * | 1991-06-13 | 1993-01-12 | Pacific Biotech, Inc. | Assay for the detection of specific ligands |
DE4121493A1 (de) * | 1991-06-28 | 1993-01-07 | Draegerwerk Ag | Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen |
FI92882C (fi) * | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
FR2725023B1 (fr) * | 1994-09-28 | 1997-01-31 | Gks Technologies | Diagnostic direct d'haptenes |
JP3010699U (ja) * | 1994-10-29 | 1995-05-02 | 株式会社ニッポンジーン | 直接採尿の可能なクロマト式検査装置 |
FR2917171A1 (fr) * | 2007-06-07 | 2008-12-12 | Biosynex Sarl | Methode de detection d'une molecule d'interet dans un echantillon liquide. |
CN102095860B (zh) * | 2011-01-25 | 2013-12-18 | 厦门大学附属中山医院 | 梅毒特异性IgG抗体免疫印迹试剂盒及其制备方法 |
WO2021099550A1 (de) | 2019-11-22 | 2021-05-27 | Nano Scale Machining GmbH | Fluidmaschine, insbesondere hydromaschine |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2644249A1 (de) * | 1976-09-30 | 1978-04-06 | Abbott Lab | Reaktive matrices |
US4320111A (en) * | 1977-06-14 | 1982-03-16 | American Home Products Corporation | Immunologic compositions methods of preparation and use |
US4189304A (en) * | 1978-10-27 | 1980-02-19 | Miles Laboratories, Inc. | Device and method for detecting myoglobin |
US4331650A (en) * | 1980-07-18 | 1982-05-25 | Science Research Center, Inc. | Identification of reagins in the blood serum of allergen sensitized vertebrates |
JPS5818167A (ja) * | 1981-07-24 | 1983-02-02 | Fuji Photo Film Co Ltd | 分析フイルム及びこれを用いる分析方法 |
US4446232A (en) * | 1981-10-13 | 1984-05-01 | Liotta Lance A | Enzyme immunoassay with two-zoned device having bound antigens |
US4447546A (en) * | 1982-08-23 | 1984-05-08 | Myron J. Block | Fluorescent immunoassay employing optical fiber in capillary tube |
DE3484505D1 (de) * | 1983-12-19 | 1991-05-29 | Daiichi Pure Chemicals Co Ltd | Immuntest. |
-
1985
- 1985-02-08 IT IT19443/85A patent/IT1200382B/it active
-
1986
- 1986-02-02 HU HU862003A patent/HUT56632A/hu unknown
- 1986-02-02 EP EP86901372A patent/EP0243370A1/en not_active Withdrawn
- 1986-02-02 JP JP61501288A patent/JPS62501989A/ja active Pending
- 1986-02-02 WO PCT/EP1986/000055 patent/WO1986004683A1/en active IP Right Grant
- 1986-02-02 AU AU55118/86A patent/AU5511886A/en not_active Abandoned
- 1986-02-05 DD DD86286799A patent/DD245727A5/de not_active IP Right Cessation
- 1986-02-07 ES ES551760A patent/ES8802256A1/es not_active Expired
-
1987
- 1987-07-17 MW MW52/87A patent/MW5287A1/xx unknown
- 1987-07-22 OA OA59169A patent/OA08640A/xx unknown
- 1987-08-05 FI FI873398A patent/FI85194C/fi not_active IP Right Cessation
- 1987-08-13 ES ES557662A patent/ES8900067A1/es not_active Expired
-
1988
- 1988-01-11 RO RO131733A patent/RO100056A2/ro unknown
- 1988-01-15 ES ES557802A patent/ES8802258A1/es not_active Expired
- 1988-01-15 ES ES557803A patent/ES8802259A1/es not_active Expired
- 1988-02-01 ES ES557818A patent/ES8802260A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8802260A1 (es) | 1988-04-16 |
EP0243370A1 (en) | 1987-11-04 |
OA08640A (en) | 1988-11-30 |
ES8900067A1 (es) | 1988-11-16 |
IT1200382B (it) | 1989-01-18 |
RO100056B1 (ro) | 1990-10-30 |
HUT56632A (en) | 1991-09-30 |
IT8519443A0 (it) | 1985-02-08 |
FI85194B (fi) | 1991-11-29 |
ES8802259A1 (es) | 1988-04-16 |
ES557803A0 (es) | 1988-04-16 |
ES557662A0 (es) | 1988-11-16 |
DD245727A5 (de) | 1987-05-13 |
JPS62501989A (ja) | 1987-08-06 |
ES8802258A1 (es) | 1988-04-16 |
ES551760A0 (es) | 1988-04-16 |
RO100056A2 (ro) | 1991-03-23 |
FI873398A (fi) | 1987-08-05 |
ES557802A0 (es) | 1988-04-16 |
WO1986004683A1 (en) | 1986-08-14 |
FI873398A0 (fi) | 1987-08-05 |
MW5287A1 (en) | 1988-11-09 |
ES557818A0 (es) | 1988-04-16 |
AU5511886A (en) | 1986-08-26 |
ES8802256A1 (es) | 1988-04-16 |
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