FI834478A7 - Viruslääkkeinä käyttökelpoisia isoksatsoleja ja niiden valmistus. - Google Patents

Viruslääkkeinä käyttökelpoisia isoksatsoleja ja niiden valmistus. Download PDF

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Publication number
FI834478A7
FI834478A7 FI834478A FI834478A FI834478A7 FI 834478 A7 FI834478 A7 FI 834478A7 FI 834478 A FI834478 A FI 834478A FI 834478 A FI834478 A FI 834478A FI 834478 A7 FI834478 A7 FI 834478A7
Authority
FI
Finland
Prior art keywords
antivirals
preparation
isoxazoles
useful
isoxazoles useful
Prior art date
Application number
FI834478A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI834478A0 (fi
FI834478L (fi
Inventor
Guy Dominic Diana
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FI834478A0 publication Critical patent/FI834478A0/fi
Publication of FI834478L publication Critical patent/FI834478L/fi
Publication of FI834478A7 publication Critical patent/FI834478A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI834478A 1982-12-13 1983-12-07 Viruslääkkeinä käyttökelpoisia isoksatsoleja ja niiden valmistus. FI834478A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44906082A 1982-12-13 1982-12-13
US06/542,871 US4451476A (en) 1982-12-13 1983-10-17 Isoxazoles as antiviral agents

Publications (3)

Publication Number Publication Date
FI834478A0 FI834478A0 (fi) 1983-12-07
FI834478L FI834478L (fi) 1984-06-14
FI834478A7 true FI834478A7 (fi) 1984-06-14

Family

ID=27035582

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834478A FI834478A7 (fi) 1982-12-13 1983-12-07 Viruslääkkeinä käyttökelpoisia isoksatsoleja ja niiden valmistus.

Country Status (11)

Country Link
US (1) US4451476A (enExample)
EP (1) EP0111345A3 (enExample)
KR (1) KR840006981A (enExample)
AU (1) AU2196683A (enExample)
DK (1) DK563083A (enExample)
ES (1) ES527954A1 (enExample)
FI (1) FI834478A7 (enExample)
GR (1) GR79091B (enExample)
IL (1) IL70360A0 (enExample)
NO (1) NO834502L (enExample)
PT (1) PT77773B (enExample)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002960A (en) * 1983-08-29 1991-03-26 Sterling Drug, Inc. N-haloalkyl-4-(isoxazol-5-yl)alkoxy benzamides
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
CA1299176C (en) * 1985-07-02 1992-04-21 Guy Dominic Diana Process for preparing isoxazole and furan derivatives
NZ209209A (en) * 1983-08-29 1988-02-12 Sterling Drug Inc Substituted phenyl-aliphatic isoxazole derivatives and pharmaceutical compositions
ZA846525B (en) * 1983-08-29 1985-04-24 Sterling Drug Inc (substituted)phenyl-aliphatic-isoxazoles useful as antiviral agents and preparation thereof
FI83782C (fi) * 1985-05-17 1991-08-26 Chemie Linz Ag Foerfarande foer framstaellning av farmakologiskt vaerdefulla substituerande isoxazolderivat.
ZW19786A1 (en) * 1985-10-17 1988-05-18 Hoffmann La Roche Heterocyclic compounds
US4929630A (en) * 1986-03-14 1990-05-29 Syntex (U.S.A.) Inc. Transglutaminase inhibitors
US4912120A (en) * 1986-03-14 1990-03-27 Syntex (U.S.A.) Inc. 3,5-substituted 4,5-dihydroisoxazoles as transglutaminase inhibitors
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
US5051437A (en) * 1986-06-24 1991-09-24 Sterling Drug Inc. Thiazolylphenoxyalkylisoxazoles, related compounds, and their use as antiviral agents
MY102282A (en) * 1987-01-28 1992-05-15 Cl Pharma Isoxazole derivatives with antiviral activities and pharmaceutical products containing these.
EP0287959B1 (de) * 1987-04-21 1993-04-28 BASF Aktiengesellschaft p-Phenoxy-phenoxymethyl-fünfring-heteroaromaten
US4992433A (en) * 1987-11-23 1991-02-12 Janssen Pharmaceutica N.V. Novel pyridazinamine derivatives
DE3742266A1 (de) * 1987-12-12 1989-06-22 Basf Ag 2-tert.-butyl-5-isoxazolylmethylthio-3(2h)-pyridazin-3-on-derivate
GB8807275D0 (en) * 1988-03-26 1988-04-27 Synphar Lab Inc Chemical compounds
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
DE68929096T2 (de) 1988-09-01 2000-05-11 Bayer Corp., Pittsburgh Menschliches Rhinovirusrezeptorprotein, das die Virusinfektionsanfälligkeit hemmt
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
GB8911158D0 (en) * 1989-05-16 1989-07-05 Janssen Pharmaceutica Nv Antiviral pyridazinamines
US5070090A (en) * 1989-05-15 1991-12-03 Janssen Pharmaceutica N.V. Antipicorpaviral herterocyclic-substituted morpholinyl alkylphenol ethers
NZ234760A (en) * 1989-08-18 1991-09-25 Sterling Drug Inc Antiviral oxazole compounds and compositions
US4942241A (en) * 1989-08-21 1990-07-17 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5175178A (en) * 1989-08-21 1992-12-29 Sterling Drug Inc. 1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US5110821A (en) * 1989-08-18 1992-05-05 Sterling Drug Inc. 1,3,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
US4945164A (en) * 1989-08-18 1990-07-31 Sterling Drug Inc. 1,3,4-Oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents and intermediates thereof
JO1645B1 (en) * 1989-12-26 1991-11-27 شركة جانسين فارماسوتيكا ان. في Pyridazine compounds are antibacterial viruses
EP0468257B1 (en) * 1990-07-20 1999-09-01 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5871733A (en) * 1990-07-20 1999-02-16 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5514679A (en) * 1994-05-13 1996-05-07 Sterling Winthrop Inc. Therapeutic phenoxyalklpyridazines and intermediates therefor
AUPQ105499A0 (en) * 1999-06-18 1999-07-08 Biota Scientific Management Pty Ltd Antiviral agents
AUPR213700A0 (en) * 2000-12-18 2001-01-25 Biota Scientific Management Pty Ltd Antiviral agents
CA2459375A1 (en) * 2001-08-29 2003-03-13 Viropharma Incorporated Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK129164B (da) * 1970-09-11 1974-09-02 Thomae Gmbh Dr K Analogifremgangsmåde til fremstilling af 3-alkyl-5-aryloxymethylisoxazoler eller syreadditionssalte deraf.
US4268878A (en) * 1979-06-01 1981-05-19 New World Computer Company, Inc. Gas circulation and filtration apparatus for magnetic disc recording systems
US4268678A (en) * 1979-09-04 1981-05-19 Sterling Drug Inc. 4-(Arylaliphatic)isoxazoles

Also Published As

Publication number Publication date
EP0111345A2 (en) 1984-06-20
FI834478A0 (fi) 1983-12-07
EP0111345A3 (en) 1986-01-08
US4451476A (en) 1984-05-29
PT77773A (en) 1984-01-01
FI834478L (fi) 1984-06-14
NO834502L (no) 1984-06-14
DK563083A (da) 1984-06-14
AU2196683A (en) 1984-06-21
IL70360A0 (en) 1984-03-30
GR79091B (enExample) 1984-10-02
DK563083D0 (da) 1983-12-07
ES527954A1 (es) 1985-11-01
PT77773B (en) 1986-04-17
KR840006981A (ko) 1984-12-04

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: STERLING DRUG INC