FI831998L - Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat - Google Patents
Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivatInfo
- Publication number
- FI831998L FI831998L FI831998A FI831998A FI831998L FI 831998 L FI831998 L FI 831998L FI 831998 A FI831998 A FI 831998A FI 831998 A FI831998 A FI 831998A FI 831998 L FI831998 L FI 831998L
- Authority
- FI
- Finland
- Prior art keywords
- pyrazinonderivat
- farming
- framework
- pharmaceutical active
- pharmaceutical
- Prior art date
Links
- 238000009313 farming Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8216437 | 1982-06-05 | ||
GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
FI831998A0 FI831998A0 (fi) | 1983-06-03 |
FI831998L true FI831998L (fi) | 1983-12-06 |
Family
ID=26283037
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI831998A FI831998L (fi) | 1982-06-05 | 1983-06-03 | Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat |
Country Status (15)
Country | Link |
---|---|
US (2) | US4514568A (fr) |
EP (1) | EP0096517A3 (fr) |
KR (1) | KR840005111A (fr) |
AU (1) | AU1527583A (fr) |
DD (1) | DD209818A5 (fr) |
DK (1) | DK247783A (fr) |
ES (2) | ES8500244A1 (fr) |
FI (1) | FI831998L (fr) |
GR (1) | GR79299B (fr) |
JO (1) | JO1255B1 (fr) |
NO (1) | NO832016L (fr) |
PL (1) | PL242354A1 (fr) |
PT (1) | PT76791B (fr) |
RO (1) | RO86851B (fr) |
ZW (1) | ZW12783A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | 1−置換アルキル1,2−ジヒドロ−2−ピラジノン誘導体 |
US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA2726917C (fr) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utile dans le traitement de troubles gastro-intestinaux, d'une inflammation, d'un cancer et d'autres troubles |
WO2010009319A2 (fr) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
CA2770454A1 (fr) * | 2009-08-19 | 2011-02-24 | Ambit Biosciences Corporation | Composes biaryles et procedes d'utilisation de ceux-ci |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US9580471B2 (en) | 2011-03-01 | 2017-02-28 | Synergy Pharmaceuticals, Inc. | Process of preparing guanylate cyclase C agonists |
KR20150023722A (ko) * | 2012-06-12 | 2015-03-05 | 애브비 인코포레이티드 | 피리디논 및 피리다지논 유도체 |
US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
WO2014151200A2 (fr) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions utiles pour le traitement de troubles gastro-intestinaux |
EP2970384A1 (fr) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼcの超高純度アゴニスト、その作成および使用方法 |
JP6694385B2 (ja) | 2013-08-09 | 2020-05-13 | アーデリクス,インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
WO2020237096A1 (fr) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combinaison pour baisser le phosphate sérique chez un patient |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/fr not_active Withdrawn
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 ES ES522962A patent/ES8500244A1/es not_active Expired
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 FI FI831998A patent/FI831998L/fi not_active Application Discontinuation
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Application Discontinuation
-
1984
- 1984-02-24 ES ES530024A patent/ES8707507A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
GR79299B (fr) | 1984-10-22 |
ES522962A0 (es) | 1984-10-01 |
AU1527583A (en) | 1983-12-08 |
PT76791B (en) | 1986-01-24 |
EP0096517A3 (fr) | 1985-04-03 |
FI831998A0 (fi) | 1983-06-03 |
JO1255B1 (en) | 1985-04-20 |
ES530024A0 (es) | 1985-12-01 |
RO86851B (ro) | 1985-05-31 |
ZW12783A1 (en) | 1983-08-24 |
PL242354A1 (en) | 1984-12-17 |
DK247783D0 (da) | 1983-06-01 |
KR840005111A (ko) | 1984-11-03 |
US4556711A (en) | 1985-12-03 |
RO86851A (fr) | 1985-05-20 |
US4514568A (en) | 1985-04-30 |
DD209818A5 (de) | 1984-05-23 |
DK247783A (da) | 1983-12-06 |
ES8500244A1 (es) | 1984-10-01 |
ES8707507A1 (es) | 1985-12-01 |
NO832016L (no) | 1983-12-06 |
EP0096517A2 (fr) | 1983-12-21 |
PT76791A (en) | 1983-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: SMITH KLINE & FRENCH LABORATORIES |