FI831998A7 - Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. - Google Patents
Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. Download PDFInfo
- Publication number
- FI831998A7 FI831998A7 FI831998A FI831998A FI831998A7 FI 831998 A7 FI831998 A7 FI 831998A7 FI 831998 A FI831998 A FI 831998A FI 831998 A FI831998 A FI 831998A FI 831998 A7 FI831998 A7 FI 831998A7
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- pharmaceutically active
- pyrazinone derivatives
- pyrazinone
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8216437 | 1982-06-05 | ||
| GB838300476A GB8300476D0 (en) | 1983-01-08 | 1983-01-08 | Heterocyclic compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI831998A0 FI831998A0 (fi) | 1983-06-03 |
| FI831998L FI831998L (fi) | 1983-12-06 |
| FI831998A7 true FI831998A7 (fi) | 1983-12-06 |
Family
ID=26283037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI831998A FI831998A7 (fi) | 1982-06-05 | 1983-06-03 | Menetelmä farmaseuttisesti aktiivisten pyratsinonijohdannaisten valmistamiseksi. |
Country Status (15)
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4657906A (en) * | 1982-06-05 | 1987-04-14 | Smith Kline & French Laboratories Ltd. | Heterocyclic compounds having inotropic activity |
| GB8332313D0 (en) * | 1983-12-02 | 1984-01-11 | Smith Kline French Lab | Chemical compounds |
| US4595766A (en) * | 1984-10-26 | 1986-06-17 | Ciba-Geigy Corporation | Process for the preparation of an indoline carboxylic acid |
| US4697016A (en) * | 1984-10-26 | 1987-09-29 | Ciba-Geigy Corporation | Intermediates for the preparation of a carboxylic acid |
| JPS62198671A (ja) * | 1986-02-25 | 1987-09-02 | Toyo Jozo Co Ltd | １−置換アルキル１，２−ジヒドロ−２−ピラジノン誘導体 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CN103601792B (zh) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂 |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP2321341B1 (en) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US20130035326A1 (en) * | 2009-08-19 | 2013-02-07 | Ambit Biosciences Corporation | Biaryl compounds and methods of use thereof |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| CN108676076A (zh) | 2011-03-01 | 2018-10-19 | 辛纳吉制药公司 | 制备鸟苷酸环化酶c激动剂的方法 |
| JP6215315B2 (ja) * | 2012-06-12 | 2017-10-18 | アッヴィ・インコーポレイテッド | ピリジノンおよびピリダジノン誘導体 |
| HK1218629A1 (zh) | 2013-02-25 | 2017-03-03 | Bausch Health Ireland Limited | 用於结肠清洁的鸟苷酸环化酶受体激动剂 |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
| MX375926B (es) | 2013-08-09 | 2025-03-07 | Ardelyx Inc | Compuestos y metodos para inhibir el transporte de fosfato. |
| EP3972599A1 (en) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3745161A (en) * | 1970-04-20 | 1973-07-10 | Merck & Co Inc | Phenyl-hydroxy-pyrazine carboxylic acids and derivatives |
-
1983
- 1983-05-27 EP EP83303059A patent/EP0096517A3/en not_active Withdrawn
- 1983-06-01 GR GR71530A patent/GR79299B/el unknown
- 1983-06-01 PT PT76791A patent/PT76791B/pt unknown
- 1983-06-01 JO JO19831255A patent/JO1255B1/en active
- 1983-06-01 DK DK247783A patent/DK247783A/da not_active Application Discontinuation
- 1983-06-01 AU AU15275/83A patent/AU1527583A/en not_active Abandoned
- 1983-06-02 US US06/500,484 patent/US4514568A/en not_active Expired - Fee Related
- 1983-06-02 US US06/500,486 patent/US4556711A/en not_active Expired - Lifetime
- 1983-06-03 ES ES522962A patent/ES8500244A1/es not_active Expired
- 1983-06-03 FI FI831998A patent/FI831998A7/fi not_active Application Discontinuation
- 1983-06-03 DD DD25173683A patent/DD209818A5/de unknown
- 1983-06-03 NO NO832016A patent/NO832016L/no unknown
- 1983-06-03 RO RO111170A patent/RO86851B/ro unknown
- 1983-06-03 ZW ZW127/83A patent/ZW12783A1/xx unknown
- 1983-06-03 PL PL24235483A patent/PL242354A1/xx unknown
- 1983-06-04 KR KR1019830002511A patent/KR840005111A/ko not_active Withdrawn
-
1984
- 1984-02-24 ES ES530024A patent/ES530024A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| US4556711A (en) | 1985-12-03 |
| RO86851B (ro) | 1985-05-31 |
| FI831998L (fi) | 1983-12-06 |
| RO86851A (ro) | 1985-05-20 |
| ES522962A0 (es) | 1984-10-01 |
| PT76791A (en) | 1983-07-01 |
| AU1527583A (en) | 1983-12-08 |
| DK247783D0 (da) | 1983-06-01 |
| PL242354A1 (en) | 1984-12-17 |
| ES8707507A1 (es) | 1985-12-01 |
| FI831998A0 (fi) | 1983-06-03 |
| ES8500244A1 (es) | 1984-10-01 |
| US4514568A (en) | 1985-04-30 |
| EP0096517A3 (en) | 1985-04-03 |
| ZW12783A1 (en) | 1983-08-24 |
| GR79299B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1984-10-22 |
| DK247783A (da) | 1983-12-06 |
| EP0096517A2 (en) | 1983-12-21 |
| NO832016L (no) | 1983-12-06 |
| ES530024A0 (es) | 1985-12-01 |
| DD209818A5 (de) | 1984-05-23 |
| JO1255B1 (en) | 1985-04-20 |
| KR840005111A (ko) | 1984-11-03 |
| PT76791B (en) | 1986-01-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Application withdrawn [patent] |
Owner name: SMITH KLINE & FRENCH LABORATORIES |