FI830078A7 - Askorbiinihappoeettereitä ja niitä lähellä olevia yhdisteitä. - Google Patents

Askorbiinihappoeettereitä ja niitä lähellä olevia yhdisteitä. Download PDF

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Publication number
FI830078A7
FI830078A7 FI830078A FI830078A FI830078A7 FI 830078 A7 FI830078 A7 FI 830078A7 FI 830078 A FI830078 A FI 830078A FI 830078 A FI830078 A FI 830078A FI 830078 A7 FI830078 A7 FI 830078A7
Authority
FI
Finland
Prior art keywords
ascorbic acid
related compounds
acid ethers
ethers
compounds
Prior art date
Application number
FI830078A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI830078L (fi
FI830078A0 (fi
Inventor
Gary Allen Koppel
Russell Lavern Barton
Jesse Robert Bewley
Stephen Lyle Briggs
Joseph Wayne Parton
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI830078A0 publication Critical patent/FI830078A0/fi
Publication of FI830078L publication Critical patent/FI830078L/fi
Publication of FI830078A7 publication Critical patent/FI830078A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/62Three oxygen atoms, e.g. ascorbic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI830078A 1982-01-15 1983-01-10 Askorbiinihappoeettereitä ja niitä lähellä olevia yhdisteitä. FI830078A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33934482A 1982-01-15 1982-01-15

Publications (3)

Publication Number Publication Date
FI830078A0 FI830078A0 (fi) 1983-01-10
FI830078L FI830078L (fi) 1983-07-16
FI830078A7 true FI830078A7 (fi) 1983-07-16

Family

ID=23328588

Family Applications (1)

Application Number Title Priority Date Filing Date
FI830078A FI830078A7 (fi) 1982-01-15 1983-01-10 Askorbiinihappoeettereitä ja niitä lähellä olevia yhdisteitä.

Country Status (16)

Country Link
EP (1) EP0086554A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS58131978A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR840003247A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU1035183A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1181078A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD209455A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK14283A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (2) ES518968A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI830078A7 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2114571A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR77897B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL67646A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (1) PL240125A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT76083B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
RO (1) RO86439B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA83173B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552895A (en) * 1983-03-14 1985-11-12 Eli Lilly And Company Furo[3,2-b]furan-2-(3H)-ones
JPS6058973A (ja) * 1983-09-13 1985-04-05 Mitsubishi Yuka Yakuhin Kk γ−プチロラクトン誘導体及びそれを有効成分とする免疫調節剤
WO1986007592A1 (en) * 1985-06-18 1986-12-31 Takeda Chemical Industries, Ltd. Ascorbic acid derivatives, process for their preparation, and preparations containing same
WO1986006720A1 (en) * 1985-05-17 1986-11-20 Takeda Chemical Industries, Ltd. Ascorbic acid derivatives, production thereof, and pharmaceutical preparation therefrom
JPS60130582A (ja) * 1983-12-19 1985-07-12 Takeda Chem Ind Ltd 食品用酸化防止剤,アスコルビン酸誘導体およびその製造法
JPS60139619A (ja) * 1983-12-27 1985-07-24 Mutsuyuki Kochi O−ベンジリデン−アスコルビン酸又はその塩よりなる抗腫瘍剤
JP2515556B2 (ja) * 1986-08-29 1996-07-10 武田薬品工業株式会社 ヒドロキシブテノライド誘導体およびその製造法
JPH0730066B2 (ja) * 1988-03-09 1995-04-05 株式会社日本ハイポックス アスコルビン酸誘導体及びアスコルビン酸誘導体からなる抗酸化剤
JP2752080B2 (ja) * 1988-03-09 1998-05-18 株式会社日本ハイポックス アスコルビン酸誘導体及びその製造方法並びにアスコルビン酸誘導体からなる抗酸化剤
ES2099064T3 (es) 1988-09-01 1997-05-16 Takeda Chemical Industries Ltd Derivados de fumagillol.
JP3058282B2 (ja) * 1989-09-11 2000-07-04 株式会社日本ハイポックス アスコルビン酸誘導体
US5095126A (en) * 1990-01-12 1992-03-10 Ohio State University Research Foundation Efficient synthesis for optically pure stereogenically labile 4-substituted-2-hydroxytetronic acids
EP0471805B1 (de) * 1990-03-07 1995-08-02 F. Hoffmann-La Roche Ag Verfahren zur herstellung von derivaten der ascorbinsäure
EP0446539A1 (en) * 1990-03-16 1991-09-18 Merrell Dow Pharmaceuticals Inc. Novel ascorbic acid derivatives
US5270336A (en) * 1990-03-16 1993-12-14 Merrell Dow Pharmaceuticals Inc. Ascorbic acid derivatives
JPH0429989A (ja) * 1990-05-24 1992-01-31 Nisshin Flour Milling Co Ltd L―アスコルビン酸誘導体の製造法
GB9026114D0 (en) * 1990-11-30 1991-01-16 Norsk Hydro As New compounds
GB9201274D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
GB9201275D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds
TW325997B (en) * 1993-02-02 1998-02-01 Senju Pharma Co Pharmaceutical composition for preventing and treating retinal diseases
RU2126398C1 (ru) * 1993-02-05 1999-02-20 Плива, Фармацеутска, Кемийска, Прехрамбена и Козметичка Индустрия Дионичко Друштво Загреб Производные аминоаскорбиновой кислоты, способы их получения и производные галоидаскорбиновой кислоты
US6114355A (en) * 1993-03-01 2000-09-05 D'amato; Robert Methods and compositions for inhibition of angiogenesis
US6228879B1 (en) 1997-10-16 2001-05-08 The Children's Medical Center Methods and compositions for inhibition of angiogenesis
US5629327A (en) * 1993-03-01 1997-05-13 Childrens Hospital Medical Center Corp. Methods and compositions for inhibition of angiogenesis
US6908910B2 (en) 1993-08-06 2005-06-21 The Children's Medical Center Corporation Estrogenic compounds as anti-mitotic agents
US5504074A (en) 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
EP1586322B1 (en) 1996-11-05 2008-08-20 The Children's Medical Center Corporation Compositions comprising thalodimide and dexamethasone for the treatment of cancer& x9;
EP0875246A1 (en) * 1997-04-04 1998-11-04 Showa Denko Kabushiki Kaisha Pharmaceutical preparation of ascorbic acid derivatives for medical treatment of cancer
ATE244707T1 (de) * 1998-03-27 2003-07-15 Lg Chem Investment Ltd Polyethoxylierte ascorbinsäurederivate als neue antioxidantien und verfahren zu ihrer herstellung
US6673828B1 (en) 1998-05-11 2004-01-06 Children's Medical Center Corporation Analogs of 2-Phthalimidinoglutaric acid
US7087592B1 (en) 1999-08-23 2006-08-08 Entre Med, Inc. Compositions comprising purified 2-methoxyestradiol and methods of producing same
AU2001230554A1 (en) * 2000-02-01 2001-08-14 Mutsuyuki Kochi Neovascularization inhibitory compositions and method of inhibiting neovascularization
CN1422157A (zh) * 2000-03-31 2003-06-04 安吉奥金尼药品有限公司 利用血管破坏活性的分割剂量疗法
ES2261458T3 (es) * 2001-07-26 2006-11-16 Tagra Biotechnologies Ltd Derivados estabilizados del aciddo ascorbico 3-fosfato.
KR100971599B1 (ko) 2002-05-15 2010-07-20 비에이취엔 가부시끼가이샤 혈관 관련 질환의 예방 또는 치료를 위한 조성물
EP1939192A1 (en) * 2006-12-28 2008-07-02 Neuropharma S.A. Cyclopentanone derivatives, method of synthesis and uses thereof
FR2955493B1 (fr) * 2010-01-28 2012-02-24 Oreal Utilisation de derives d'acide ascorbique en coloration des fibres keratiniques humaines, composition les comprenant, procede de coloration et dispositif
JP5602456B2 (ja) * 2010-02-24 2014-10-08 日本精化株式会社 アスコルビン酸誘導体
WO2015048121A1 (en) * 2013-09-25 2015-04-02 University Of Florida Research Foundation, Inc. Vitamin c prodrugs and uses thereof
US10105407B2 (en) * 2015-06-09 2018-10-23 John P. Crow, JR. Methods of extraction of nitrosylated or nitrated derivatives of ascorbic acid from myriciaria dubia and methods of synthesis thereof
EP3383429B1 (en) 2015-11-30 2020-10-14 INSERM - Institut National de la Santé et de la Recherche Médicale Nmdar antagonists for the treatment of tumor angiogenesis

Also Published As

Publication number Publication date
RO86439A (ro) 1985-03-15
CA1181078A (en) 1985-01-15
GR77897B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-09-25
FI830078L (fi) 1983-07-16
ES525239A0 (es) 1985-01-16
DK14283D0 (da) 1983-01-14
DD209455A5 (de) 1984-05-09
ES8403118A1 (es) 1984-03-01
ES8502698A1 (es) 1985-01-16
JPS58131978A (ja) 1983-08-06
PL240125A1 (en) 1984-04-24
PT76083B (en) 1986-01-09
FI830078A0 (fi) 1983-01-10
PT76083A (en) 1983-02-01
KR840003247A (ko) 1984-08-20
EP0086554A1 (en) 1983-08-24
GB2114571A (en) 1983-08-24
ES518968A0 (es) 1984-03-01
IL67646A0 (en) 1983-05-15
ZA83173B (en) 1984-08-29
GB8300907D0 (en) 1983-02-16
RO86439B (ro) 1985-03-31
DK14283A (da) 1983-07-16
AU1035183A (en) 1983-07-21

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: ELI LILLY AND COMPANY