FI821824A0 - Nya karbacykliner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel - Google Patents
Nya karbacykliner, foerfarande foer deras framstaellning och deras anvaendning som laekemedelInfo
- Publication number
- FI821824A0 FI821824A0 FI821824A FI821824A FI821824A0 FI 821824 A0 FI821824 A0 FI 821824A0 FI 821824 A FI821824 A FI 821824A FI 821824 A FI821824 A FI 821824A FI 821824 A0 FI821824 A0 FI 821824A0
- Authority
- FI
- Finland
- Prior art keywords
- deras
- karbacykliner
- nya
- free
- foerfarande foer
- Prior art date
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 206010061216 Infarction Diseases 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Substances 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- -1 hydroxymethylene Chemical class 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000007574 infarction Effects 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C33/05—Alcohols containing rings other than six-membered aromatic rings
- C07C33/12—Alcohols containing rings other than six-membered aromatic rings containing five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/40—Esters thereof
- C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/4015—Esters of acyclic unsaturated acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyrane Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Drawers Of Furniture (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813121155 DE3121155A1 (de) | 1981-05-22 | 1981-05-22 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FI821824A0 true FI821824A0 (fi) | 1982-05-21 |
Family
ID=6133385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI821824A FI821824A0 (fi) | 1981-05-22 | 1982-05-21 | Nya karbacykliner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4497830A (el) |
| EP (1) | EP0069692B1 (el) |
| JP (1) | JPS57206655A (el) |
| AT (1) | ATE32705T1 (el) |
| AU (1) | AU559925B2 (el) |
| CA (1) | CA1223582A (el) |
| CS (1) | CS226448B2 (el) |
| DD (1) | DD202528A5 (el) |
| DE (2) | DE3121155A1 (el) |
| DK (1) | DK152750C (el) |
| ES (1) | ES512441A0 (el) |
| FI (1) | FI821824A0 (el) |
| GR (1) | GR82685B (el) |
| HU (1) | HU188173B (el) |
| IE (1) | IE53888B1 (el) |
| IL (1) | IL65847A0 (el) |
| MX (1) | MX155864A (el) |
| NO (1) | NO155536C (el) |
| NZ (1) | NZ200633A (el) |
| PH (1) | PH20454A (el) |
| YU (1) | YU109082A (el) |
| ZA (1) | ZA823551B (el) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5190964A (en) * | 1978-04-03 | 1993-03-02 | Schering Aktiengesellschaft | 5-fluorocarbacyclins, their preparation and pharmaceutical use |
| CA1201712A (en) * | 1980-02-28 | 1986-03-11 | Paul A. Aristoff | Carbacyclin analogs |
| DE3048906A1 (de) * | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3306123A1 (de) * | 1983-02-18 | 1984-09-06 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3405181A1 (de) * | 1984-02-10 | 1985-08-22 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| CA1241324A (en) * | 1984-03-08 | 1988-08-30 | Paul A. Aristoff | Interphenylene carbacyclin derivatives |
| US5801200A (en) * | 1984-03-19 | 1998-09-01 | The Picower Institute For Medical Research | Methods and materials for the diagnosis and treatment of conditions such as stroke |
| DE69019431T2 (de) * | 1989-07-27 | 1995-09-14 | Ueno Seiyaku Oyo Kenkyujo Kk | Verwendung von 15-Keto-Prostansäure-Derivaten zur Herstellung eines Medikaments für die Verbesserung der Ausscheidung des Kaliumions. |
| DE4104606C1 (el) * | 1991-02-12 | 1992-10-15 | Schering Ag Berlin Und Bergkamen, 1000 Berlin, De |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4032576A (el) * | 1976-01-08 | 1977-06-28 | ||
| JPS5495552A (en) * | 1978-01-06 | 1979-07-28 | Sankyo Co Ltd | Prostacyline derivative and its preparation |
| GB2013661B (en) * | 1978-01-26 | 1982-11-10 | Erba Farmitalia | 9-deoxy-9 -methylene isosteres of pgi2 |
| US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
| US4238414A (en) * | 1978-02-13 | 1980-12-09 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-6a-carba-PGI2 compounds |
| JPS54119441A (en) * | 1978-03-09 | 1979-09-17 | Sumitomo Chem Co Ltd | Novel bicyclooctane derivative |
| GB2017699B (en) * | 1978-03-31 | 1983-01-12 | Ono Pharmaceutical Co | 6,9-methano-pgi2 analogues |
| DE2845770A1 (de) * | 1978-10-19 | 1980-04-30 | Schering Ag | Neue prostacyclin-derivate und verfahren zu ihrer herstellung |
| US4306076A (en) * | 1980-04-23 | 1981-12-15 | The Upjohn Company | Inter-phenylene CBA compounds |
| US4349689A (en) * | 1980-12-22 | 1982-09-14 | The Upjohn Company | Methano carbacyclin analogs |
-
1981
- 1981-05-22 DE DE19813121155 patent/DE3121155A1/de not_active Ceased
-
1982
- 1982-05-14 PH PH27303A patent/PH20454A/en unknown
- 1982-05-17 NZ NZ200633A patent/NZ200633A/en unknown
- 1982-05-19 DD DD82239993A patent/DD202528A5/de unknown
- 1982-05-19 AT AT82730069T patent/ATE32705T1/de not_active IP Right Cessation
- 1982-05-19 EP EP82730069A patent/EP0069692B1/de not_active Expired
- 1982-05-19 CA CA000403276A patent/CA1223582A/en not_active Expired
- 1982-05-19 DE DE8282730069T patent/DE3278159D1/de not_active Expired
- 1982-05-20 GR GR68208A patent/GR82685B/el unknown
- 1982-05-21 JP JP57085082A patent/JPS57206655A/ja active Granted
- 1982-05-21 YU YU01090/82A patent/YU109082A/xx unknown
- 1982-05-21 NO NO821693A patent/NO155536C/no unknown
- 1982-05-21 IE IE1218/82A patent/IE53888B1/en unknown
- 1982-05-21 ZA ZA823551A patent/ZA823551B/xx unknown
- 1982-05-21 DK DK230082A patent/DK152750C/da not_active IP Right Cessation
- 1982-05-21 CS CS823764A patent/CS226448B2/cs unknown
- 1982-05-21 ES ES512441A patent/ES512441A0/es active Granted
- 1982-05-21 HU HU821645A patent/HU188173B/hu unknown
- 1982-05-21 IL IL65847A patent/IL65847A0/xx unknown
- 1982-05-21 FI FI821824A patent/FI821824A0/fi not_active Application Discontinuation
- 1982-05-24 US US06/381,609 patent/US4497830A/en not_active Expired - Fee Related
- 1982-05-24 MX MX192833A patent/MX155864A/es unknown
- 1982-05-24 AU AU84072/82A patent/AU559925B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IE821218L (en) | 1982-11-22 |
| ZA823551B (en) | 1983-03-30 |
| AU8407282A (en) | 1982-11-25 |
| AU559925B2 (en) | 1987-03-26 |
| JPH0368849B2 (el) | 1991-10-30 |
| US4497830A (en) | 1985-02-05 |
| DK152750C (da) | 1988-10-03 |
| DE3278159D1 (en) | 1988-04-07 |
| PH20454A (en) | 1987-01-14 |
| CA1223582A (en) | 1987-06-30 |
| YU109082A (en) | 1984-12-31 |
| NO821693L (no) | 1982-11-23 |
| NZ200633A (en) | 1986-08-08 |
| NO155536B (no) | 1987-01-05 |
| EP0069692B1 (de) | 1988-03-02 |
| DD202528A5 (de) | 1983-09-21 |
| DK230082A (da) | 1982-11-23 |
| HU188173B (en) | 1986-03-28 |
| JPS57206655A (en) | 1982-12-18 |
| IL65847A0 (en) | 1982-08-31 |
| GR82685B (el) | 1985-11-25 |
| NO155536C (no) | 1987-04-15 |
| DE3121155A1 (de) | 1982-12-09 |
| MX155864A (es) | 1988-05-13 |
| ES8304056A1 (es) | 1983-03-01 |
| DK152750B (da) | 1988-05-09 |
| IE53888B1 (en) | 1989-04-12 |
| CS226448B2 (en) | 1984-03-19 |
| EP0069692A1 (de) | 1983-01-12 |
| ES512441A0 (es) | 1983-03-01 |
| ATE32705T1 (de) | 1988-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE3169305D1 (en) | Carbacyclins, process for their preparation and their utilization as pharmaceutical preparations | |
| FI821824A0 (fi) | Nya karbacykliner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel | |
| ATE101392T1 (de) | Fluorsubstituierte benzolderivate. | |
| HUT38346A (en) | Process for producing azabicyclo-heptane derivatives pharmaceutical compositions containing them | |
| ES522632A0 (es) | Procedimiento para la preparacion de carbaciclinas. | |
| SE7811761L (sv) | 4,5,6,7-tetrahydroimidazo-(4,5-c),pyridinderivat och forfarande for deras framstellning | |
| FI850519A0 (fi) | Nya karbacykliner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |
Owner name: SCHERING AKTIENGESELLSCHAFT |