FI812106L - Nya imidazolderivat foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter - Google Patents

Nya imidazolderivat foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter

Info

Publication number
FI812106L
FI812106L FI812106A FI812106A FI812106L FI 812106 L FI812106 L FI 812106L FI 812106 A FI812106 A FI 812106A FI 812106 A FI812106 A FI 812106A FI 812106 L FI812106 L FI 812106L
Authority
FI
Finland
Prior art keywords
groups
alkyl
residues
alkoxy
thienyl
Prior art date
Application number
FI812106A
Other languages
English (en)
Inventor
Ulrich Niedballa
Irmgard Boettcher
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of FI812106L publication Critical patent/FI812106L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
FI812106A 1980-07-03 1981-07-03 Nya imidazolderivat foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter FI812106L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803025484 DE3025484A1 (de) 1980-07-03 1980-07-03 Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
FI812106L true FI812106L (fi) 1982-01-04

Family

ID=6106465

Family Applications (1)

Application Number Title Priority Date Filing Date
FI812106A FI812106L (fi) 1980-07-03 1981-07-03 Nya imidazolderivat foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter

Country Status (17)

Country Link
US (2) US4402960A (fi)
EP (1) EP0043788B1 (fi)
JP (1) JPS5775973A (fi)
AT (1) ATE16281T1 (fi)
AU (1) AU7249481A (fi)
CA (1) CA1169063A (fi)
DD (1) DD206152A5 (fi)
DE (2) DE3025484A1 (fi)
DK (1) DK293381A (fi)
ES (1) ES503678A0 (fi)
FI (1) FI812106L (fi)
GR (1) GR78231B (fi)
IE (1) IE52822B1 (fi)
IL (1) IL63190A0 (fi)
NO (1) NO812265L (fi)
PT (1) PT73280B (fi)
ZA (1) ZA814540B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3025484A1 (de) * 1980-07-03 1982-02-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3141063A1 (de) * 1981-10-13 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US5300519A (en) * 1988-07-06 1994-04-05 The University Of Sheffield Immunosuppressive agents
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
CA2003283A1 (en) * 1988-12-05 1990-06-05 C. Anne Higley Imidazoles for the treatment of atherosclerosis
GB8907656D0 (en) * 1989-04-05 1989-05-17 May & Baker Ltd New compositions of matter
US5011851A (en) * 1990-02-13 1991-04-30 Bristol-Myers Squibb Co. Imidazole carboxylic acids and esters and inhibition of blood platelet aggregation therewith
GB9005966D0 (en) * 1990-03-16 1990-05-09 May & Baker Ltd New compositions of matter
US5441515A (en) * 1993-04-23 1995-08-15 Advanced Cardiovascular Systems, Inc. Ratcheting stent
AU8757098A (en) * 1997-06-30 1999-02-10 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE19842833B4 (de) 1998-09-18 2005-04-14 Merckle Gmbh 2-Arylalkylthio-imidazole, 2-Arylalkenylthio-imidazole und 2-Arylalkinylthio-imidazole als Entzündungs-Hemmstoffe und Hemmstoffe der Cytokin-Freisetzung
DE10107683A1 (de) * 2001-02-19 2002-08-29 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
DE10238045A1 (de) * 2002-08-20 2004-03-04 Merckle Gmbh Chem.-Pharm. Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie
EP1894925A1 (en) * 2006-08-24 2008-03-05 Merckle Gmbh Imidazole compounds having an antiinflammatory effect

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1509975A (fr) * 1965-10-21 1968-01-19 Geigy Ag J R Dérivés de l'imidazole et leur préparation
US3651080A (en) * 1969-11-07 1972-03-21 Ciba Geigy Corp Certain substituted 2-alkylmercaptoimidazole derivatives
US4190666A (en) * 1975-08-11 1980-02-26 E. I. Du Pont De Nemours And Company Anti-inflammatory 4,5-diarly-2-(substituted-thio)imidazoles and their corresponding sulfoxides and sulfones
US4215217A (en) * 1975-10-29 1980-07-29 Sk&F Lab Co. Process for preparing 4-substituted imidazole compounds
US4182769A (en) * 1977-02-09 1980-01-08 E. I. Du Pont De Nemours And Company Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones
EP0004648B1 (de) * 1978-04-11 1982-08-25 Ciba-Geigy Ag Neue Mercaptoimidazolderivate, Verfahren zu deren Herstellung, Mercaptoimidazolderivate zur Behandlung entzündlicher Erkrankungen und diese enthaltende pharmazeutische Präparate
DE2960506D1 (en) * 1978-04-24 1981-10-29 Dumex Ltd As Arylimidazoles, their synthesis and pharmaceutical or veterinary preparations containing them
DE2823197A1 (de) * 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
DE3025484A1 (de) * 1980-07-03 1982-02-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4330552A (en) * 1980-11-06 1982-05-18 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-arylthioimidazoles

Also Published As

Publication number Publication date
DE3025484A1 (de) 1982-02-04
PT73280B (de) 1982-07-22
AU7249481A (en) 1982-01-07
JPS5775973A (en) 1982-05-12
IL63190A0 (en) 1981-09-13
CA1169063A (en) 1984-06-12
IE52822B1 (en) 1988-03-16
ES8301220A1 (es) 1982-12-01
DK293381A (da) 1982-01-04
ATE16281T1 (de) 1985-11-15
ZA814540B (en) 1982-07-28
EP0043788B1 (de) 1985-10-30
GR78231B (fi) 1984-09-26
EP0043788A1 (de) 1982-01-13
IE811484L (en) 1982-01-03
ES503678A0 (es) 1982-12-01
DE3172757D1 (en) 1985-12-05
NO812265L (no) 1982-01-04
DD206152A5 (de) 1984-01-18
US4528298A (en) 1985-07-09
US4402960A (en) 1983-09-06
JPH0254343B2 (fi) 1990-11-21
PT73280A (de) 1981-07-01

Similar Documents

Publication Publication Date Title
FI812106L (fi) Nya imidazolderivat foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska produkter
MX5680E (es) Procedimiento para la preparacion de 2-(2-alcoxietil)-2'-hidroxi-6,7-benzomorfanos
MX9203687A (es) Nuevos derivados de 6&-metilprednisolona, su obtencion y uso.
FI822203A0 (fi) Nya 2-aryl-3,4-diaza-bicyklo/4,n,0/-alken-(2)-oner-(5), foerfarande foer deras framstaellning och dessa innehaollande laekemedel
SE8003815L (sv) Alkyl-ketohexopyranosid-derivat
ATE15662T1 (de) Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
FR2386544A1 (fr) Procede pour la preparation de derives d'imidazodiazepine
SE7909916L (sv) Beta,gamma-dihydropolyprenylalkoholer och farmaceutiska kompositioner innehallande desamma
NO164351C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-alkyl-l-fenyl-2-piperazinoalkylpyrazolin-3-on-forbindelser.
ES497693A0 (es) Procedimiento para la obtencion de derivados de benzotiazol
SE8004933L (sv) Radiommunoanalys av pteriner och nya pterinderivat lempade for detta endamal
FI890187A (fi) Foerfarande foer framstaellning av hydroxialkylerande foereningar, saolunda erhaollna nya foereningar och deras anvaendning.
ES505897A0 (es) Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a)pirimidina
ES540260A0 (es) Procedimiento para preparar derivados de 2-alcoxiaminosulfo-nilbencenosulfonilurea
ES511869A0 (es) Procedimiento para preparar derivados de acido 5-aminometil-2,3-dihidro-2-oxo-1h-imidazol-4-carboxilico.
ES508757A0 (es) "procedimiento para la preparacion de acidos antranilicos sustituidos con radicales basicos"
DK379581A (da) Fremgangsmaade til fremstilling af acylderivater
SE8107680L (sv) Piperazinderivat och forfarande for framstellning derav
ES458092A1 (es) Procedimiento para la obtencion de derivados de la n1, n4- dioxo-quinoxalina.
SE8801166D0 (sv) Substituted 1,3-dioxolane and 1,3-dioxane derivatives, processes for the production and their use
SE8002937L (sv) Nytt n,n'-difenylhydrazinderivat och forfarande for framstellning derav
JPS56154474A (en) Preparation of piperazine derivative
SE7909980L (sv) I-amino-indolin-derivat, deras framstellning och farmaceutiska kompositioner innehallande desamma
ES456093A1 (es) Un procedimiento para la preparacion de nuevos derivados de 1-tiazolinil bencimidazoles 5(6)-sustituidos.

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: SCHERING AKTIENGESELLSCHAFT