FI781350A - Benzylpyrimidiner och foerfarande foer deras framstaellning - Google Patents

Benzylpyrimidiner och foerfarande foer deras framstaellning

Info

Publication number
FI781350A
FI781350A FI781350A FI781350A FI781350A FI 781350 A FI781350 A FI 781350A FI 781350 A FI781350 A FI 781350A FI 781350 A FI781350 A FI 781350A FI 781350 A FI781350 A FI 781350A
Authority
FI
Finland
Prior art keywords
benzylpyrimidiner
foerfarande foer
och foerfarande
deras framstaellning
foer deras
Prior art date
Application number
FI781350A
Other languages
English (en)
Finnish (fi)
Inventor
Ivan Kompis
Alexander Eduard Wick
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU77269A external-priority patent/LU77269A1/xx
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI781350A publication Critical patent/FI781350A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/48Two nitrogen atoms
    • C07D239/49Two nitrogen atoms with an aralkyl radical, or substituted aralkyl radical, attached in position 5, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups
    • C07C45/66Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI781350A 1977-05-05 1978-05-02 Benzylpyrimidiner och foerfarande foer deras framstaellning FI781350A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU77269A LU77269A1 (pt) 1977-05-05 1977-05-05
CH265078A CH642637A5 (en) 1977-05-05 1978-03-10 Benzylpyrimidines and process for their preparation

Publications (1)

Publication Number Publication Date
FI781350A true FI781350A (fi) 1978-11-06

Family

ID=25691041

Family Applications (1)

Application Number Title Priority Date Filing Date
FI781350A FI781350A (fi) 1977-05-05 1978-05-02 Benzylpyrimidiner och foerfarande foer deras framstaellning

Country Status (19)

Country Link
US (2) US4203980A (pt)
JP (1) JPS53137978A (pt)
AT (1) ATA320578A (pt)
BR (1) BR7802834A (pt)
CA (1) CA1084498A (pt)
DE (1) DE2819212A1 (pt)
DK (1) DK143447C (pt)
ES (1) ES469450A1 (pt)
FI (1) FI781350A (pt)
FR (1) FR2389611B1 (pt)
GB (1) GB1583817A (pt)
IL (1) IL54598A0 (pt)
IT (1) IT1096292B (pt)
MC (1) MC1194A1 (pt)
NL (1) NL7804776A (pt)
NO (1) NO781587L (pt)
NZ (1) NZ187115A (pt)
PT (1) PT67994B (pt)
SE (1) SE7805186L (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4515948A (en) * 1973-09-12 1985-05-07 Hoffmann-La Roche Inc. 2,4-Diamino-5-(4-amino and 4-dimethylamino-3,5-dimethoxy benzyl)pyrimidines
IT1138146B (it) * 1981-08-11 1986-09-17 Proter Spa Processo per la produzione della 2,4-diammino-(3,5-dimetossi-4-metos sietossi-benzil)-pirimidina
EA016054B1 (ru) * 2006-06-16 2012-01-30 Х. Лундбекк А/С Кристаллические формы 4-[2-(4-метилфенилсульфанил)фенил] пиперидина с объединенным ингибированием повторного поглощения серотонина и норадреналина для лечения невропатической боли

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996356A (en) * 1969-07-02 1976-12-07 Hoffmann-La Roche Inc. Composition containing 5-sulfanilamido-3,4-dimethylisoxazole and a trimethoxybenzyl pyrimidine
BE795023A (fr) * 1972-02-07 1973-08-06 Hoffmann La Roche Nouvelles benzylpyrimidines
US3985876A (en) * 1973-01-05 1976-10-12 Burroughs Wellcome Co. Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine
US3931181A (en) * 1973-07-27 1976-01-06 Hoffmann-La Roche Inc. 2,4-Diamino-5-benzylpyrimidines
CH598231A5 (pt) 1973-07-27 1978-04-28 Hoffmann La Roche
US4033962A (en) * 1975-06-26 1977-07-05 Hoffman-La Roche Inc. 2,4-Diamino-pyrimidine derivatives and processes

Also Published As

Publication number Publication date
GB1583817A (en) 1981-02-04
DK143447C (da) 1982-01-04
IT1096292B (it) 1985-08-26
NZ187115A (en) 1980-08-26
CA1084498A (en) 1980-08-26
NL7804776A (nl) 1978-11-07
BR7802834A (pt) 1979-02-13
MC1194A1 (fr) 1979-02-23
US4203980A (en) 1980-05-20
DE2819212A1 (de) 1978-11-16
US4254286A (en) 1981-03-03
PT67994B (en) 1980-05-05
IT7823093A0 (it) 1978-05-05
ATA320578A (de) 1980-03-15
FR2389611A1 (pt) 1978-12-01
SE7805186L (sv) 1978-11-06
ES469450A1 (es) 1979-10-01
NO781587L (no) 1978-11-07
DK195678A (da) 1978-11-06
DK143447B (da) 1981-08-24
IL54598A0 (en) 1978-07-31
FR2389611B1 (pt) 1980-06-20
JPS53137978A (en) 1978-12-01
PT67994A (en) 1978-06-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: F. HOFFMANN-LA ROCHE & CO.