FI72123B - 7-/d(-)-alfa-(4-etyl-2,3-dioxo-1-piperazinkarboxiamido)-alfa-(4-hydroxifenyl)acetamido/-3-/5-(1-metyl-1,2,3,4-tetrazolyl)tiometyl/- 3-cefem-4-karboxylsyrans n,n-dimetylacetamidadduktoch foerfarande foer framstaellning av denna - Google Patents

7-/d(-)-alfa-(4-etyl-2,3-dioxo-1-piperazinkarboxiamido)-alfa-(4-hydroxifenyl)acetamido/-3-/5-(1-metyl-1,2,3,4-tetrazolyl)tiometyl/- 3-cefem-4-karboxylsyrans n,n-dimetylacetamidadduktoch foerfarande foer framstaellning av denna Download PDF

Info

Publication number
FI72123B
FI72123B FI852810A FI852810A FI72123B FI 72123 B FI72123 B FI 72123B FI 852810 A FI852810 A FI 852810A FI 852810 A FI852810 A FI 852810A FI 72123 B FI72123 B FI 72123B
Authority
FI
Finland
Prior art keywords
formula
compound
dimethylacetamide
ethyl
methyl
Prior art date
Application number
FI852810A
Other languages
English (en)
Finnish (fi)
Other versions
FI852810A0 (fi
FI852810L (fi
FI72123C (sv
Inventor
Isamu Saikawa
Shuntaro Takano
Kaishu Momonoi
Isamu Takakura
Chiaki Kutani
Kiyoshi Tanaka
Kenshin Hayashi
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52115127A external-priority patent/JPS6056718B2/ja
Priority claimed from JP52115126A external-priority patent/JPS6056717B2/ja
Priority claimed from FI782912A external-priority patent/FI71743C/sv
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Publication of FI852810A0 publication Critical patent/FI852810A0/fi
Publication of FI852810L publication Critical patent/FI852810L/fi
Publication of FI72123B publication Critical patent/FI72123B/fi
Application granted granted Critical
Publication of FI72123C publication Critical patent/FI72123C/sv

Links

Landscapes

  • Cephalosporin Compounds (AREA)

Claims (3)

1. Förfarande för framställning av en N,N-dimetyl-acetaraidaddukt av 7- £d (-)-di - (4-etyl-2,3-dioxo-l-piperazin-karboxamido) -<jC - (4-hydroxifenyl) acetamido7 -3- £*5- (1-metyl-5 1,2,3,4-tetrazolyl)tiometyl7 -A3-cefem-4-karhoxylsyra med formeln (I) °V-f° 0 C2H5 "N\_/ _CONH'CH-CONH '-, «j— Ϊ.,οη,,.νΧοη, ,1, ίο Λ ψ Too„ 2 i„3 OH kännetecknat därav, att man omsätter en förening med formeln (III) “'•77^77
20 COOH CH^ med ett reaktivt derivat av en förening med formeln (IV) 0. ^—K _c Γ H "N N-CONH-CH-COOH 2 5 \ / 1 λ (IV. OH 30 i närvaro av Ν,Ν-dimetylacetamid som lösningsmedel.
FI852810A 1977-09-27 1985-07-17 7-/D(-)- -(4-etyl-2,3-dioxo-1 -piperazinkarboxiamido)- -(4-hydroxifeny l)acetamido/-3-/5-(1-metyl -1,2,3,4-tetrazolyl)tiometyl/- 3-cefem-4-ka rboxylsyrans N,N-dimetylacetamidaddukt och förfarande förframställnin g av denna. FI72123C (sv)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP11512677 1977-09-27
JP52115127A JPS6056718B2 (ja) 1977-09-27 1977-09-27 セフアロスポリンの製法
JP52115126A JPS6056717B2 (ja) 1977-09-27 1977-09-27 セフアロスポリンのｎ，ｎ−ジメチルアセトアミド付加体及びその製法
JP11512777 1977-09-27
FI782912A FI71743C (sv) 1977-09-27 1978-09-25 Nytt förfarande för framställning av 7-/D(-)- -(4-etyl-2,3-dioxo-1-pip erazinkarboxiamido)- (4-hydroxifenyl)-acetamido/-3-/5-(1-metyl-1,2,3,4 -tetrazolyl)tiometyl// 3-cefem-4-karboxylsyra.
FI782912 1978-09-25

Publications (4)

Publication Number Publication Date
FI852810A0 FI852810A0 (fi) 1985-07-17
FI852810L FI852810L (fi) 1985-07-17
FI72123B true FI72123B (fi) 1986-12-31
FI72123C FI72123C (sv) 1987-04-13

Family

ID=27241018

Family Applications (1)

Application Number Title Priority Date Filing Date
FI852810A FI72123C (sv) 1977-09-27 1985-07-17 7-/D(-)- -(4-etyl-2,3-dioxo-1 -piperazinkarboxiamido)- -(4-hydroxifeny l)acetamido/-3-/5-(1-metyl -1,2,3,4-tetrazolyl)tiometyl/- 3-cefem-4-ka rboxylsyrans N,N-dimetylacetamidaddukt och förfarande förframställnin g av denna.

Country Status (1)

Country Link
FI (1) FI72123C (sv)

Also Published As

Publication number Publication date
FI852810A0 (fi) 1985-07-17
FI852810L (fi) 1985-07-17
FI72123C (sv) 1987-04-13

Similar Documents

Publication Publication Date Title
FI74019C (sv) Förfarande för framställning av 7beta-acylamino-3-substitueradmetyl-3- cefem-4-karboxylsyraderivat
KR870000848B1 (ko) 세팔로스포린 유도체의 제조방법
EP0333154B1 (en) Process for the preparation of cephem derivatives
JPS6153359B2 (sv)
US5081116A (en) Cephalosporin derivatives
KR870000612B1 (ko) 세팔로스포린 중간생성물의 제조방법
KR100407584B1 (ko) 세포독심 프록세틸 디아스테레오이성체의 제조 방법
KR910008350B1 (ko) 세팔로스포린 에스테르 유도체의 제조방법
US5142041A (en) Cephalosporin intermediates
FI72123B (fi) 7-/d(-)-alfa-(4-etyl-2,3-dioxo-1-piperazinkarboxiamido)-alfa-(4-hydroxifenyl)acetamido/-3-/5-(1-metyl-1,2,3,4-tetrazolyl)tiometyl/- 3-cefem-4-karboxylsyrans n,n-dimetylacetamidadduktoch foerfarande foer framstaellning av denna
US4179502A (en) 7[2-Hydroxyiminoacetamido]cephalosporins
FI66186B (fi) Foerfarande foer framstaellning av penicillansyra- och cefalosporansyraderivat
US4699981A (en) Cephalosporin derivatives
US4959495A (en) Process for the preparation of intermediates used to produce aminothiazoloximino cephalosporins
US4237280A (en) Intermediate for cephalosporin type compound
US4107440A (en) Intermediates for preparing substituted phenylglycylcephalosporins
US4490370A (en) Naphthylglycyl cephalosporin derivatives
DD201142A5 (de) Verfahren zur herstellung von bistetrazolyl-methylsubstituierten cephalosporiantibiotika
US4044047A (en) Intermediates for preparing substituted phenylglycylcephalosporins
IT8922575A1 (it) Procedimento per la preparazione dell&#39;acido 7-(d-2-amino-2-fenilacetam ido)-3-cloro-3-cefem-4-carbossilico monoidrato e intermedio
US4497811A (en) 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same
DE3444367C2 (sv)
EP0098615B1 (en) 1-oxadethiacephalosporin compound and antibacterial agent containing the same
JPS643865B2 (sv)
US5066799A (en) Intermediates for the preparation of aminothiazoloximino cephalosporins

Legal Events

Date Code Title Description
MA Patent expired

Owner name: TOYAMA CHEMICAL CO., LTD.