FI65621B - Foerfarande foer framstaellning av som cns-aktiva medel anvaendbara 2-(4,4-difluorfenyl-butyl)-6h-oktahydropyrazino(1,2-c)pyrimidin-6-oner - Google Patents

Foerfarande foer framstaellning av som cns-aktiva medel anvaendbara 2-(4,4-difluorfenyl-butyl)-6h-oktahydropyrazino(1,2-c)pyrimidin-6-oner

Info

Publication number
FI65621B
FI65621B FI782370A FI782370A FI65621B FI 65621 B FI65621 B FI 65621B FI 782370 A FI782370 A FI 782370A FI 782370 A FI782370 A FI 782370A FI 65621 B FI65621 B FI 65621B
Authority
FI
Finland
Prior art keywords
framstarabilation
octahydropyrazine
difluorphenyl
anvaendbara
meda
Prior art date
Application number
FI782370A
Other languages
English (en)
Other versions
FI782370A (fi
FI65621C (fi
Inventor
Anders Karl Konrad Bjoerk
Bengt Eric Sigvard Kjellberg
Aina Lisbeth Abramo
Sven Erik Harry Hernestam
Original Assignee
Ferrosan Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrosan Ab filed Critical Ferrosan Ab
Publication of FI782370A publication Critical patent/FI782370A/fi
Publication of FI65621B publication Critical patent/FI65621B/fi
Application granted granted Critical
Publication of FI65621C publication Critical patent/FI65621C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI782370A 1977-09-05 1978-08-01 Foerfarande foer framstaellning av som cns-aktiva medel anvaendbara 2-(4,4-difluorfenyl-butyl)-6h-oktahydropyrazino-(1,2-c) pyrimidin-6-oner FI65621C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3690477 1977-09-05
GB3690477 1977-09-05

Publications (3)

Publication Number Publication Date
FI782370A FI782370A (fi) 1979-03-06
FI65621B true FI65621B (fi) 1984-02-29
FI65621C FI65621C (fi) 1984-06-11

Family

ID=10392108

Family Applications (1)

Application Number Title Priority Date Filing Date
FI782370A FI65621C (fi) 1977-09-05 1978-08-01 Foerfarande foer framstaellning av som cns-aktiva medel anvaendbara 2-(4,4-difluorfenyl-butyl)-6h-oktahydropyrazino-(1,2-c) pyrimidin-6-oner

Country Status (17)

Country Link
US (1) US4183933A (fi)
JP (1) JPS5452097A (fi)
AT (1) AT364365B (fi)
BE (1) BE870227A (fi)
CA (1) CA1102323A (fi)
CH (1) CH637133A5 (fi)
DE (1) DE2837089A1 (fi)
DK (1) DK149365C (fi)
ES (1) ES473070A1 (fi)
FI (1) FI65621C (fi)
FR (1) FR2401923A1 (fi)
IT (1) IT1159108B (fi)
LU (1) LU80192A1 (fi)
MX (1) MX5281E (fi)
NL (1) NL7809016A (fi)
NO (1) NO154194C (fi)
SE (1) SE442115B (fi)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3560503A (en) * 1968-09-18 1971-02-02 Council Scient Ind Res Di-lower alkyl-substituted octahydropyrazinopyrimidinones
US3752816A (en) * 1969-06-10 1973-08-14 Sherwin Williams Co Certain 3-substituted-pyrido(3,2-d)pyrimidine 2,4-(1h,3h)-diones
GB1284582A (en) * 1969-11-10 1972-08-09 Council Scient Ind Res Substituted piperazinopyrimidinones
FR2103465A1 (en) * 1970-08-24 1972-04-14 Hokuriku Pharmaceutical Benzhydril-pyridodiazepines - as antihistaminics and anticholinergics from dihaloalkylpiperidines and arylalkylamines with condensing agent
US3965257A (en) * 1972-01-28 1976-06-22 Richardson-Merrell Inc. Compositions and methods for the treatment of the symptoms of histamine induced allergic reactions
US3922275A (en) * 1972-11-09 1975-11-25 Hisamitsu Pharmaceutical Co Pyrido{8 2,3-D{9 {0 pyrimidine-2,4(1H,3H)-diones
DE2523730A1 (de) * 1974-06-12 1976-02-12 Hisamitsu Pharmaceutical Co Pyrido eckige klammer auf 2,3-d eckige klammer zu pyrimidinonen

Also Published As

Publication number Publication date
ES473070A1 (es) 1979-04-01
DK149365C (da) 1986-11-24
NO154194B (no) 1986-04-28
US4183933A (en) 1980-01-15
DK149365B (da) 1986-05-20
CA1102323A (en) 1981-06-02
FI782370A (fi) 1979-03-06
ATA638178A (de) 1981-03-15
FR2401923B1 (fi) 1982-05-14
NO154194C (no) 1986-08-06
BE870227A (fr) 1979-03-05
MX5281E (es) 1983-06-02
IT7827103A0 (it) 1978-08-29
SE7809288L (sv) 1979-03-06
NL7809016A (nl) 1979-03-07
IT1159108B (it) 1987-02-25
LU80192A1 (de) 1979-06-01
SE442115B (sv) 1985-12-02
AT364365B (de) 1981-10-12
FR2401923A1 (fr) 1979-03-30
JPS5452097A (en) 1979-04-24
DK386778A (da) 1979-03-06
FI65621C (fi) 1984-06-11
CH637133A5 (de) 1983-07-15
DE2837089A1 (de) 1979-03-22
NO782995L (no) 1979-03-06
JPS5725555B2 (fi) 1982-05-29

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: AB FERROSAN