FI57760C - Foerfarande foer framstaellning av tillvaext av tumoerer foerhindrande n-formylleurocin - Google Patents

Foerfarande foer framstaellning av tillvaext av tumoerer foerhindrande n-formylleurocin Download PDF

Info

Publication number
FI57760C
FI57760C FI347/74A FI34774A FI57760C FI 57760 C FI57760 C FI 57760C FI 347/74 A FI347/74 A FI 347/74A FI 34774 A FI34774 A FI 34774A FI 57760 C FI57760 C FI 57760C
Authority
FI
Finland
Prior art keywords
leurosine
formyl
mixture
vincristine
benzene
Prior art date
Application number
FI347/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI57760B (fi
Inventor
Karola Jovanovics
Kalman Szasz
Bela Kellner
Laszlo Nemeth
Zsuzsa Relle
Emil Bittner
Eszter Dezseri
Janos Eles
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI57760B publication Critical patent/FI57760B/fi
Application granted granted Critical
Publication of FI57760C publication Critical patent/FI57760C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI347/74A 1973-02-16 1974-02-07 Foerfarande foer framstaellning av tillvaext av tumoerer foerhindrande n-formylleurocin FI57760C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HURI000502 1973-02-16
HURI502A HU165986B (US06657057-20031202-C00006.png) 1973-02-16 1973-02-16

Publications (2)

Publication Number Publication Date
FI57760B FI57760B (fi) 1980-06-30
FI57760C true FI57760C (fi) 1980-10-10

Family

ID=11000914

Family Applications (1)

Application Number Title Priority Date Filing Date
FI347/74A FI57760C (fi) 1973-02-16 1974-02-07 Foerfarande foer framstaellning av tillvaext av tumoerer foerhindrande n-formylleurocin

Country Status (25)

Country Link
US (3) US4189432A (US06657057-20031202-C00006.png)
JP (1) JPS5221520B2 (US06657057-20031202-C00006.png)
AT (1) AT332566B (US06657057-20031202-C00006.png)
BE (1) BE811110A (US06657057-20031202-C00006.png)
BG (1) BG21415A3 (US06657057-20031202-C00006.png)
CA (1) CA1029017A (US06657057-20031202-C00006.png)
CH (1) CH592101A5 (US06657057-20031202-C00006.png)
CS (1) CS181737B2 (US06657057-20031202-C00006.png)
DD (1) DD110276A5 (US06657057-20031202-C00006.png)
DE (1) DE2404120C3 (US06657057-20031202-C00006.png)
DK (1) DK138459B (US06657057-20031202-C00006.png)
ES (1) ES423289A1 (US06657057-20031202-C00006.png)
FI (1) FI57760C (US06657057-20031202-C00006.png)
FR (1) FR2218095B1 (US06657057-20031202-C00006.png)
GB (1) GB1412932A (US06657057-20031202-C00006.png)
HU (1) HU165986B (US06657057-20031202-C00006.png)
IL (1) IL43963A (US06657057-20031202-C00006.png)
NL (1) NL159390B (US06657057-20031202-C00006.png)
NO (1) NO139441C (US06657057-20031202-C00006.png)
PL (1) PL88630B1 (US06657057-20031202-C00006.png)
RO (1) RO65486A (US06657057-20031202-C00006.png)
SE (1) SE407687B (US06657057-20031202-C00006.png)
SU (1) SU576951A3 (US06657057-20031202-C00006.png)
YU (1) YU35893B (US06657057-20031202-C00006.png)
ZA (1) ZA741015B (US06657057-20031202-C00006.png)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (US06657057-20031202-C00006.png) * 1974-12-30 1978-07-21 Anvar
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
HU178706B (en) * 1979-04-23 1982-06-28 Richter Gedeon Vegyeszet Process for preparing bis-indole alkaloids and acid addition salts thereof
FR2651348B1 (US06657057-20031202-C00006.png) * 1989-08-04 1993-01-22 Adir
US6326402B1 (en) 1998-08-12 2001-12-04 Octamer, Inc. Methods for treating viral infections using a compound capable of inhibiting microtubules

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3392173A (en) * 1964-03-09 1968-07-09 Lilly Co Eli Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation
US4065457A (en) * 1973-05-19 1977-12-27 Beecham Group Limited 4-Hydroxy-3-nitro-carbostyril compounds

Also Published As

Publication number Publication date
HU165986B (US06657057-20031202-C00006.png) 1974-12-28
IL43963A (en) 1976-04-30
DD110276A5 (US06657057-20031202-C00006.png) 1974-12-12
DE2404120B2 (de) 1977-11-10
US4279916A (en) 1981-07-21
ATA65374A (de) 1976-01-15
BG21415A3 (US06657057-20031202-C00006.png) 1976-05-20
DE2404120A1 (de) 1974-08-29
US4279915A (en) 1981-07-21
DK138459C (US06657057-20031202-C00006.png) 1979-02-19
FR2218095B1 (US06657057-20031202-C00006.png) 1978-01-06
CS181737B2 (en) 1978-03-31
ZA741015B (en) 1975-02-26
FI57760B (fi) 1980-06-30
DK138459B (da) 1978-09-11
RO65486A (ro) 1980-06-15
IL43963A0 (en) 1974-05-16
NO740228A (no) 1974-08-19
ES423289A1 (es) 1976-04-16
YU13374A (en) 1981-02-28
YU35893B (en) 1981-08-31
BE811110A (fr) 1974-05-29
NL159390B (nl) 1979-02-15
AT332566B (de) 1976-10-11
NO139441C (no) 1979-03-14
CH592101A5 (US06657057-20031202-C00006.png) 1977-10-14
PL88630B1 (en) 1976-09-30
JPS5221520B2 (US06657057-20031202-C00006.png) 1977-06-10
NO139441B (no) 1978-12-04
CA1029017A (en) 1978-04-04
JPS5040599A (US06657057-20031202-C00006.png) 1975-04-14
SU576951A3 (ru) 1977-10-15
NL7401416A (US06657057-20031202-C00006.png) 1974-08-20
GB1412932A (en) 1975-11-05
SE407687B (sv) 1979-04-09
AU6428274A (en) 1975-07-10
FR2218095A1 (US06657057-20031202-C00006.png) 1974-09-13
US4189432A (en) 1980-02-19
DE2404120C3 (de) 1978-07-20

Similar Documents

Publication Publication Date Title
US5620985A (en) Antimitotic binary alkaloid derivatives from catharanthus roseus
US5453520A (en) Baccatine III derivatives
TWI432191B (zh) 分離自藤黃樹脂的化合物以及包含有此等化合物的藥學組成物
EP0686154B1 (en) Novel use as anti-inflammatory agents for bis-heterocyclic compounds and pharmaceutical compositions thereof
FI57760C (fi) Foerfarande foer framstaellning av tillvaext av tumoerer foerhindrande n-formylleurocin
US4298525A (en) Bis-indole-alkaloid
Kende et al. Synthesis and Reactivity in the Benzocalicene Series1
US6403636B1 (en) Xanthone compounds, their preparation and use as medicament
SK83494A3 (en) Alkaloides of mappia foetida, method of their production, their use for production of pharmaceutical agents and pharmaceutical agents and pharmaceutical agents containing them
Ferlin et al. New water soluble pyrroloquinoline derivatives as new potential anticancer agents
Banerjee et al. Further sesquiterpene lactones from Elephantopus mollis and Centratherum punctatum
EP0447703A1 (en) Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine
US5578646A (en) Pharmaceutically acceptable anthracene compounds
US4279816A (en) N-Formyl leurosine derivatives in a dosage form effective for treating lymphoid leukemia
EP0001920B1 (en) Vincaleukoblastine derivatives, a process for their preparation, pharmaceutical formulations containing them and the derivatives for use as antimitotic agents
CN110698443A (zh) 一种shp2小分子选择性抑制剂及其在制备抗肺癌药物中的应用
WO1998049895A1 (en) Selectively cytotoxic acetogenin compounds
HU180725B (en) Process for preparing dimeric derivatives of indole-dihydroindole-oxazolidinone-dione derivatives
US4514330A (en) Carbon-7-substituted atinomycin D analogue
Szlaużys et al. SYNTHESIS OF NEW INDOLE-URACIL BIOCONJUGATES WITH POTENT BIOLOGICAL ACTIVITY
KR810001489B1 (ko) 빈카 알카로이드의 옥사졸리딘 디온 유도체의 제조방법
Jones et al. Pyrroloindole analogues of ellipticine. The synthesis and DNA intercalative properties of 5, 10-dihyhdro-5, 10, dimethyl-2, 5, 10-triazadibenzo [a, e] pentalene
US4195022A (en) 4-Desacetoxy-4α-hydroxyvinblastine and related compounds
Bonjouklian et al. Facile intramolecular photoaddition and oxidation dimerization of hapalindole E, a naturally occurring isonitrile-containing indole
IE47489B1 (en) 4-desacetoxy-4a-hydroxyindole-dihydroindoles,pharmaceutical formulations containing them and their use as antimitotic agents