FI55194B - Foerfarande foer framstaellning av 6-substituerade 4-amino-1,2-dihydro-1-hydroxi-2-iminopyrimidiner - Google Patents
Foerfarande foer framstaellning av 6-substituerade 4-amino-1,2-dihydro-1-hydroxi-2-iminopyrimidinerInfo
- Publication number
- FI55194B FI55194B FI828/71A FI82871A FI55194B FI 55194 B FI55194 B FI 55194B FI 828/71 A FI828/71 A FI 828/71A FI 82871 A FI82871 A FI 82871A FI 55194 B FI55194 B FI 55194B
- Authority
- FI
- Finland
- Prior art keywords
- iminopyrimidine
- framstation
- hydroxi
- substitutes
- dihydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Phase Diffusion Into Metallic Material Surfaces (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2435170A | 1970-03-31 | 1970-03-31 | |
| US2435170 | 1970-03-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI55194B true FI55194B (fi) | 1979-02-28 |
| FI55194C FI55194C (fi) | 1981-05-18 |
Family
ID=21820134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI828/71A FI55194C (fi) | 1970-03-31 | 1971-03-23 | Foerfarande foer framstaellning av 6-substituerade 4-amino-1,2-dihydro-1-hydroxi-2-iminopyrimidiner |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US3644364A (fi) |
| JP (1) | JPS551259B1 (fi) |
| CH (1) | CH551979A (fi) |
| DE (1) | DE2114887C3 (fi) |
| DK (2) | DK128116B (fi) |
| FI (1) | FI55194C (fi) |
| FR (1) | FR2087936A5 (fi) |
| NL (1) | NL7104019A (fi) |
| NO (2) | NO131420C (fi) |
| SE (2) | SE384504B (fi) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3931181A (en) * | 1973-07-27 | 1976-01-06 | Hoffmann-La Roche Inc. | 2,4-Diamino-5-benzylpyrimidines |
| US4013778A (en) * | 1974-08-05 | 1977-03-22 | Warner-Lambert Company | Method for reducing blood pressure |
| US4175190A (en) * | 1977-02-04 | 1979-11-20 | Hoffmann-La Roche Inc. | 6-Chloro-2,4-pyrimidine-dicarbamate-3-oxides |
| US4175189A (en) * | 1977-02-04 | 1979-11-20 | Hoffmann-La Roche Inc. | 6-Chloro-2,4-pyrimidine-dicarbamate-3-oxides |
| US5196533A (en) * | 1983-04-11 | 1993-03-23 | South Alabama Medical Science Foundation, Usa | Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines |
| HU196067B (en) * | 1986-07-10 | 1988-09-28 | Richter Gedeon Vegyeszet | Process for production of 6-amin-1,2-dihydro-1-hydroxi-2-imino-4-piperidin-piramidin |
| FI864046A (fi) * | 1986-10-07 | 1988-04-08 | Farmos Oy | Foerfarande foer framstaellning av en terapeutiskt aktiv foerening. |
| US6465514B1 (en) | 1986-12-29 | 2002-10-15 | Kenneth M. Hallam | Methods and compositions for the promotion of hair growth |
| US4927626A (en) * | 1988-10-28 | 1990-05-22 | Devillez Richard L | Method for enhancement of unguis growth |
| US4959475A (en) * | 1989-01-04 | 1990-09-25 | Lonza Ltd. | Process for the production of 2,4-diamino-6-piperidinyl-pyrimidine-3-N-oxide |
| FR2651122B1 (fr) * | 1989-08-29 | 1994-10-28 | Oreal | Compositions destinees a etre utilisees pour freiner la chute des cheveux et pour induire et stimuler leur croissance, contenant des derives de l'amino-2 pyrimidine oxyde-3 et nouveaux composes derives de l'amino-2 pyrimidine oxyde-3. |
| AU651630B2 (en) * | 1990-11-14 | 1994-07-28 | Pharmacia & Upjohn Company | 5-fluoro-2,4,6-pyrimidinetriamine compounds |
| US5502050A (en) * | 1993-11-29 | 1996-03-26 | Cornell Research Foundation, Inc. | Blocking utilization of tetrahydrobiopterin to block induction of nitric oxide synthesis |
| FR2753378B1 (fr) * | 1996-09-17 | 1998-11-20 | Oreal | Utilisation dans une composition en tant que stimulateur de tyrosinase d'au moins un derive de pyrimidine 3-oxyde, substitue en 6 |
| US20050163811A1 (en) * | 2004-01-23 | 2005-07-28 | Richard Lee | Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof |
| EP2730271B1 (en) | 2012-11-11 | 2018-01-24 | Symrise AG | Aqeuous compositions |
| CN107129470A (zh) * | 2017-06-12 | 2017-09-05 | 常州市天华制药有限公司 | 一种米诺地尔的合成与精制方法 |
| CN107235919B (zh) * | 2017-06-22 | 2020-05-12 | 安徽拜善晟制药有限公司 | 一种米诺地尔的合成工艺 |
| CN114213340B (zh) | 2022-02-22 | 2022-06-07 | 北京蓝晶微生物科技有限公司 | 2,4-二氨基嘧啶氧化物的制备方法 |
| CN115572265A (zh) * | 2022-10-10 | 2023-01-06 | 江苏海悦康医药科技有限公司 | 一种高纯度米诺地尔的绿色合成工艺 |
-
1970
- 1970-03-31 US US24351A patent/US3644364A/en not_active Expired - Lifetime
-
1971
- 1971-03-04 CH CH314471A patent/CH551979A/xx not_active IP Right Cessation
- 1971-03-04 JP JP1103771A patent/JPS551259B1/ja active Pending
- 1971-03-17 DK DK128571AA patent/DK128116B/da not_active IP Right Cessation
- 1971-03-23 FI FI828/71A patent/FI55194C/fi active
- 1971-03-25 NL NL7104019A patent/NL7104019A/xx unknown
- 1971-03-26 SE SE7317494A patent/SE384504B/xx unknown
- 1971-03-26 SE SE7103975A patent/SE384368B/xx unknown
- 1971-03-27 DE DE2114887A patent/DE2114887C3/de not_active Expired
- 1971-03-29 NO NO1160/71A patent/NO131420C/no unknown
- 1971-03-30 FR FR7111170A patent/FR2087936A5/fr not_active Expired
- 1971-11-17 DK DK564671AA patent/DK128539B/da not_active IP Right Cessation
-
1974
- 1974-04-03 NO NO741201A patent/NO140011C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7104019A (fi) | 1971-10-04 |
| SE384504B (sv) | 1976-05-10 |
| FR2087936A5 (fi) | 1971-12-31 |
| NO140011C (no) | 1979-06-20 |
| JPS551259B1 (fi) | 1980-01-12 |
| DK128539B (da) | 1974-05-20 |
| NO131420C (fi) | 1975-05-28 |
| FI55194C (fi) | 1981-05-18 |
| NO140011B (no) | 1979-03-12 |
| CH551979A (de) | 1974-07-31 |
| NO131420B (fi) | 1975-02-17 |
| SE384368B (sv) | 1976-05-03 |
| DE2114887B2 (de) | 1980-01-17 |
| DE2114887C3 (de) | 1980-09-11 |
| DE2114887A1 (de) | 1971-10-14 |
| US3644364A (en) | 1972-02-22 |
| NO741201L (no) | 1971-10-01 |
| DK128116B (da) | 1974-03-04 |
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