FI55179B - Foerfarande foer framstaellning av farmakologiskt aktiva substituerade dibensocyklohepten-karboxamider och deras syraadditionssalter - Google Patents

Foerfarande foer framstaellning av farmakologiskt aktiva substituerade dibensocyklohepten-karboxamider och deras syraadditionssalter

Info

Publication number
FI55179B
FI55179B FI175/73A FI17573A FI55179B FI 55179 B FI55179 B FI 55179B FI 175/73 A FI175/73 A FI 175/73A FI 17573 A FI17573 A FI 17573A FI 55179 B FI55179 B FI 55179B
Authority
FI
Finland
Prior art keywords
dibensocyclohepten
carboxamider
syraadditionssalter
procedure
preparation
Prior art date
Application number
FI175/73A
Other languages
English (en)
Other versions
FI55179C (fi
Inventor
Michel Vincent
Georges Remond
Michel Laubie
Original Assignee
Science Union & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union & Cie filed Critical Science Union & Cie
Publication of FI55179B publication Critical patent/FI55179B/fi
Application granted granted Critical
Publication of FI55179C publication Critical patent/FI55179C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/57Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/62Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
FI175/73A 1972-01-24 1973-01-23 Foerfarande foer framstaellning av farmakologiskt aktiva substituerade dibensocyklohepten-karboxamider och deras syra-additionssalter FI55179C (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB323772A GB1399261A (en) 1972-01-24 1972-01-24 1,3-diamino 2-propanols and process for their preparation

Publications (2)

Publication Number Publication Date
FI55179B true FI55179B (fi) 1979-02-28
FI55179C FI55179C (fi) 1979-06-11

Family

ID=9754539

Family Applications (1)

Application Number Title Priority Date Filing Date
FI175/73A FI55179C (fi) 1972-01-24 1973-01-23 Foerfarande foer framstaellning av farmakologiskt aktiva substituerade dibensocyklohepten-karboxamider och deras syra-additionssalter

Country Status (17)

Country Link
US (1) US3906040A (fi)
JP (1) JPS511706B2 (fi)
BE (1) BE794424A (fi)
CA (1) CA995212A (fi)
CH (1) CH562780A5 (fi)
DE (1) DE2303427C3 (fi)
DK (1) DK138943B (fi)
FI (1) FI55179C (fi)
FR (1) FR2169135B1 (fi)
GB (1) GB1399261A (fi)
HU (1) HU168110B (fi)
IE (1) IE37140B1 (fi)
NL (2) NL149485B (fi)
NO (1) NO141555C (fi)
SE (1) SE397190B (fi)
SU (1) SU495822A3 (fi)
ZA (1) ZA73444B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
DE2720915C2 (de) * 1977-05-10 1986-04-17 Kali-Chemie Pharma Gmbh, 3000 Hannover N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel mit diesen Verbindungen als Wirkstoff
ES469020A1 (es) * 1977-05-10 1979-09-01 Kali Chemie Pharma Gmbh Procedimiento para la preparacion de nuevos 1-acil-2-hidroxi-1,3-diaminopropanos
US6008213A (en) * 1995-06-29 1999-12-28 Smithkline Beecham Corporation Integrin receptor antagonists
JP3960482B2 (ja) * 1995-06-29 2007-08-15 スミスクライン・ビーチャム・コーポレイション インテグリン受容体アンタゴニスト
CO4920232A1 (es) * 1997-01-08 2000-05-29 Smithkline Beecham Corp Acidos aceticos dibenzo [a,d] cicloheptano con actividad antagonista del receptor de vitronectin
RU2560727C1 (ru) * 2014-09-22 2015-08-20 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Кубанский государственный университет" (ФГБОУ ВПО "КубГУ") Способ получения 1,3-дикарбонильных соединений, содержащих дибензосуберенильный фрагмент

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3287409A (en) * 1962-07-23 1966-11-22 Geigy Chem Corp 5h-dibenzo [a, d] cycloheptene-5-carboxamide
US3344185A (en) * 1962-07-30 1967-09-26 Leonard Frederick Certain amides of 5h-dibenzo [a, d] cycloheptene- and 10, 11-dihydro-5h-dibenzo [a, d] cycloheptene-5-carboxylic acid
CH443281A (de) * 1964-02-18 1967-09-15 Hoffmann La Roche Verfahren zur Herstellung von Dibenzocycloheptatrienverbindungen

Also Published As

Publication number Publication date
JPS511706B2 (fi) 1976-01-20
JPS4881846A (fi) 1973-11-01
DK138943C (fi) 1979-05-07
SE397190B (sv) 1977-10-24
ZA73444B (en) 1973-11-28
FR2169135A1 (fi) 1973-09-07
IE37140B1 (en) 1977-05-11
DE2303427C3 (de) 1979-07-26
NL7300960A (fi) 1973-07-26
AU5131673A (en) 1974-07-25
DE2303427B2 (de) 1978-11-23
BE794424A (fr) 1973-07-23
NL149485B (nl) 1976-05-17
CH562780A5 (fi) 1975-06-13
NO141555C (no) 1980-04-09
FR2169135B1 (fi) 1976-04-09
DE2303427A1 (de) 1973-08-16
FI55179C (fi) 1979-06-11
US3906040A (en) 1975-09-16
DK138943B (da) 1978-11-20
NL7601019A (nl) 1976-05-31
NO141555B (no) 1979-12-27
GB1399261A (en) 1975-07-02
SU495822A3 (ru) 1975-12-15
HU168110B (fi) 1976-02-28
IE37140L (en) 1973-07-24
CA995212A (fr) 1976-08-17

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